Search PubMed⌕ Search

Biomedical subjects

T H Turner

Publications and source records attributed to T H Turner.

27 records · Page 2Linked to original sources

Personality and theophylline pharmacokinetics.

Thirteen volunteers received an iv dose of theophylline followed by blood sampling for 8 h to calculate pharmacokinetic parameters. Ten patients with asthma undergoing chronic dosing with slow release aminophylline underwent 12 h of blood sampling to calculate theophylline clearance. Both groups completed an Eysenck Personality Inventory (EPI) from which was derived scores for neuroticism (N) and extroversion (E). Using multiple regression analysis no independent effect of either N or E score on theophylline clearance or half-life could be demonstrated.

Half-Life↗

Huntington's chorea without dementia. A problem case.

An unusual case of Huntington's Chorea, without dementia, is described. The diagnostic issues are discussed with particular reference to the problems of psychiatric assessment and management of the disease.

Dementia↗

Psychotic reactions during treatment of pituitary tumours with dopamine agonists.

Of 600 patients treated with the dopamine agonist drugs bromocriptine and lisuride for functioning pituitary tumours, eight developed drug related psychoses. Symptoms included auditory hallucinations, delusional ideas, and appreciable changes in mood. These reactions occurred with lower doses of the drugs than previously reported and remitted when treatment was stopped. The possibility of psychiatric side effects with dopamine agonist treatment should be recognised in view of the strain that may be placed on patients and their families.

Acromegaly↗