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Biomedical subjects

T H Payne

Publications and source records attributed to T H Payne.

17 recordsLinked to original sources

Computer decision support systems.

Computer decision support systems are computer applications designed to aid clinicians in making diagnostic and therapeutic decisions in patient care. They can simplify access to data needed to make decisions, provide reminders and prompts at the time of a patient encounter, assist in establishing a diagnosis and in entering appropriate orders, and alert clinicians when new patterns in patient data are recognized. Decision support systems that present patient-specific recommendations in a form that can save clinicians time have been shown to be highly effective, sustainable tools for changing clinician behavior. Designing and implementing such systems is challenging because of the computing infrastructure required, the need for patient data in a machine-processible form, and the changes to existing workflow that may result. Despite these difficulties, there is substantial evidence from trials in a wide range of clinical settings that computer decision support systems help clinicians do a better job caring for patients. As computer-based records and order-entry systems become more common, automated decision support systems will be used more broadly.

Computer Systems↗

Extending the VA CPRS electronic patient record order entry system using natural language processing techniques.

An automated practitioner order entry system was recently implemented at the VA Puget Sound Health Care System. Since the introduction of this system, we have experienced various problems, among them an increase in time required for practitioners to enter orders. In order to improve usability and acceptance of the order entry, an alternate pathway was built within CPRS that allows direct natural language based order entry. Implementation of the extension in CPRS has been made possible because of the three layers CPRS architecture and its strong object oriented models. This paper discusses the advantages and needs for a natural language based order entry system and its implementation within an existing order entry system.

Humans↗

Use of a clinical event monitor to prevent and detect medication errors.

Errors in health care facilities are common and often unrecognized. We have used our clinical event monitor to prevent and detect medication errors by scrutinizing electronic messages sent to it when any medication order is written in our facility. A growing collection of medication safety rules covering dose limit errors, laboratory monitoring, and other topics may be applied to each medication order message to provide an additional layer of protection beyond existing order checks, reminders, and alerts available within our computer-based record system. During a typical day the event monitor receives 4802 messages, of which 4719 pertain to medication orders. We have found the clinical event monitor to be a valuable tool for clinicians and quality management groups charged with improving medication safety.

Decision Support Systems, Clinical↗

The transition to automated practitioner order entry in a teaching hospital: the VA Puget Sound experience.

We recently installed an automated practitioner order entry system on our busiest inpatient wards and critical care units. The installation followed 20 months preparation in which we created the workstation, network, and host infrastructure, developed requisite policies, recruited personnel to support the system, and installed the software in areas where the pace of order entry was less intense. Since implementing automated order entry, we have experienced problems such as an increase in time required for practitioners to enter orders, workflow changes on inpatient units, difficulties with patient transfers, and others. Our user support system has been heavily used during the transition period. Software tailoring and enhancements designed to address these problems are planned, as is installation of the order entry system in remaining clinical units in our medical centers.

Attitude to Computers↗

Development of a clinical event monitor for use with the Veterans Affairs Computerized Patient Record System and other data sources.

We are developing an event monitor to operate with the Veterans Affairs Computerized Patient Record System (CPRS). The event monitor is designed to receive messages when important patient events such as posting of new results, patient movement, and orders occur. Our design separates the event monitor from CPRS itself, using communication via a network connection to receive HL7 messages, to access other data needed to run rules, and to communicate with providers by message display, electronic mail and other mechanisms. Results from operation of the event monitor using patient data in our test account show that a wide variety of data can be accessed by the event monitor with acceptable response times.

Computer Communication Networks↗

Practicing population-based care in an HMO: evaluation after 18 months.

OBJECTIVE: To determine whether population-based care in a primary care practice results in improvement in compliance with patient care guidelines. DESIGN: Time series analysis. SETTING: One primary care practice in Group Health Cooperative of Puget Sound (GHC). PARTICIPANTS: Approximately 1500 enrollees cared for by the practice. INTERVENTIONS: An ongoing approach to aid clinical planning at the level of the primary care team--population-based care--that depends on clinical guidelines, a computing system to provide epidemiologic data on guideline performance in the practice and reminders, and a process whereby the practice team analyzed and designs interventions for specific clinical problems. MAIN OUTCOME MEASURES: We compared compliance with practice guidelines for preventive care and chronic illness management at baseline and after 18 months in the intervention population with other patients in the same clinic and with patients in GHC as a whole. RESULTS: Compliance with breast cancer screening and colorectal cancer screening guidelines in the intervention population increased from baseline 32% and 18% respectively. These increases were significantly greater than in the remainder of the clinic or in GHC as a whole. CONCLUSIONS: The availability of practice-based data, clinical guidelines and a local intervention design process resulted in significant improvements in compliance with patient care guidelines.

Algorithms↗

The role of the information architect at King Faisal Specialist Hospital and Research Centre.

Successful implementation of integrated clinical information system requires modification of the institution's long range strategic plans and its personnel's behavior. The changes warrant a concerted effort on the part of many different individuals; this paper describes the role of the Information Architect whose primary functions are to steer the process to fulfill stated objectives and build consensus where divergent forces are at work. The workings of the Architect is presented in context of a unique Middle-Eastern institution currently undergoing automation of clinical information.

Academic Medical Centers↗

A comparison of four schemes for codification of problem lists.

We set out to evaluate the completeness of four major coding schemes in representation of the patient problem list: the Unified Medical Language System (UMLS, 4th edition), the Systematized Nomenclature of Medicine (SNOMED International), the Read coding system (version 2), and the International Classification of Diseases (9th Clinical Modification)(ICD-9-CM). We gathered 400 problems from patient records at primary care sites in Omaha and Seattle. Matching these against the best description found in each of the coding schemes, we asked five medical faculty reviewers to rate the matches on a five-point Likert scale assessing their satisfaction with the results. For the four schemes, we computed the following rates of dissatisfaction, satisfaction, and average scores: [table: see text] From this analysis, we conclude that UMLS and SNOMED performed substantially better in capturing the clinical content of the problem lists than READ or ICD-9-CM. No scheme could be considered comprehensive. Depending on the goal of systems developers, UMLS and SNOMED may offer different, and complementary, advantages.

Disease↗

How useful is the UMLS metathesaurus in developing a controlled vocabulary for an automated problem list?

We are developing a set of problem list phrases to be used in the automated problem list of a prototype clinical computing system. Because of the large number of terms in the Unified Medical Language System (UMLS) and the links between them, we are experimenting with the use of the UMLS as the foundation for our problem list phrase set. We have found the UMLS to be very useful for this project, but that it lacks many phases clinicians wish to include in the problem list. Internal linkages between phrases provided in the UMLS are not well suited to our needs. We plan to continue our use of the UMLS but to add problem list phrases and linkages between phrases to support browsing and decision support applications.

Ambulatory Care Information Systems↗

The ambulatory medical record project at Group Health Cooperative: what did a decade of experience teach us?

Computer-based record systems are documented to improve patient care (Barnett, 1984; McDonald & Tierney, 1988) and their importance in the future is widely accepted. The report of the Institute of Medicine on patient computer-based record systems (Detmer, 1991) will help guide the development of future computer-based record systems and will likely stimulate renewed interest in them. We believe computing systems have great value to an HMO but understand that the benefits do not come without the risk of setbacks. We plan to build on what we have learned from our decade of experience.

Ambulatory Care Information Systems↗

How well does ICD9 represent phrases used in the medical record problem list?

We are considering using the International Classification of Diseases with Clinical Modifications, Ninth Revision (ICD9) as the basis for an automated problem list for a clinical information system. To determine physician satisfaction with an ICD9 representation of phrases used in the medical record problem list, we asked 6 physicians to evaluate ICD9 representations of 332 phrases taken from medical record problem lists, using a scale of 1(extremely dissatisfied) to 5 (extremely satisfied). The mean score was 3.0; intraclass correlation for 25 phrases given to all 6 evaluators was 0.47. In 45% of the phrases the physicians were dissatisfied with the ICD9 representation. In developing an automated problem list it is desirable to improve the level of satisfaction of clinician users above this level. This could be done by modifying ICD9, using a different vocabulary to represent the problem list, or improving the method of assigning ICD9 codes.

Consumer Behavior↗

Marked elevations of serum alkaline phosphatase in patients with AIDS.

We have observed many patients with AIDS who have unexplained marked elevations in serum alkaline phosphatase. To determine the frequency of alkaline phosphatase elevations in patients with AIDS, and to identify diagnoses, medications, and demographic factors associated with such elevations, we conducted a retrospective study of the first 90 consecutive AIDS cases in hospitals affiliated with the University of Colorado Health Sciences Center in Denver, Colorado. We found elevations of alkaline phosphatase in excess of 1,000 IU/L in 17% of consecutive patients with AIDS. This level of elevation was less frequent in patients with Kaposi's sarcoma but there was otherwise no significant association with diagnoses or medications, or transmission categories for AIDS. The majority of the patients with elevations to this level did not have documented opportunistic infections or biliary tract dilatation previously described in the "cholangitis" syndrome in AIDS patients. Other explanations for these elevations for this common laboratory finding may exist.

Acquired Immunodeficiency Syndrome↗

Conducting a matched-pairs historical cohort study with a computer-based ambulatory medical record system.

We describe techniques for using the Computer-Stored Ambulatory Record (COSTAR) at the Massachusetts General Hospital to conduct a historical cohort study of the effect of nonsteroidal anti-inflammatory drugs (NSAIDs) on blood pressure control. A query language was used to identify patients satisfying clinical and data-availability criteria, to match these patients with clinically similar patients not exposed to NSAIDs, and to collect data from the COSTAR records of both groups of patients to determine any differences in outcome. We analyzed over 30,000 patient records to select 90 pairs of patients used in the study. This approach to clinical research uses data collected for purpose of patient care and so does not require the separate recording of patient data for clinical research. Using computer-based medical record systems with a query language allows selection and matching of patients using detailed demographic and clinical criteria. The ability to conduct such studies is an advantage of computer-based medical record systems over the paper record system.

Ambulatory Care↗

Do resident and staff physicians differ in the types and costs of antihypertensive drugs they select?

OBJECTIVE: To compare the types and costs of drugs prescribed by resident and staff physicians treating patients with uncomplicated essential hypertension. DESIGN: Cross-sectional study, using a computer-based medical record database. SETTING: Primary care internal medicine clinic in a large teaching hospital. PATIENTS/PARTICIPANTS: Hypertensive patients seen by ten postgraduate year-1 (PGY-1) and PGY-2 primary care internal medicine residents and four staff physicians practicing in the same clinic. MEASUREMENTS AND MAIN RESULTS: The types and costs of antihypertensive drugs prescribed for the patients treated by resident and staff physicians were compared. A larger proportion of patients of resident physicians than of staff physicians were treated with calcium channel blockers [19(15%) vs. 40(4%), p less than 0.001]; residents prescribed thiazide diuretics less frequently and beta-blockers more frequently than did staff physicians, although these differences were not significant. The estimated average wholesale price of antihypertensive drugs for patients cared for by residents was 35% higher than that for patients cared for by staff physicians ($0.73 vs. $0.54, p = 0.048). This difference was not fully explained by differences in practice composition. CONCLUSIONS: Resident physicians in this study selected more expensive medications to treat hypertension than did their faculty preceptors, even when differences in practice composition were considered.

Antihypertensive Agents↗

Postdoctoral training in medical informatics: a survey of National Library of Medicine-supported fellows.

The National Library of Medicine (NLM) funds training programs in medical informatics and plans to significantly increase the number of program sites in the future. The authors surveyed all NLM-funded trainees at the nine sites supported in the spring of 1988 to determine their backgrounds, current research interests, and career plans. Forty-three fellows were identified, of whom 39 returned a mailed questionnaire. All but four were physicians (89.7%), 82.1% had at least one year of postdoctoral clinical training, and 61.5% had completed a residency. Seventy-one percent of those completing residency had done so in internal medicine. The most common areas of current research were decision support/decision analysis, knowledge representation, and artificial intelligence. The overwhelming majority of the fellows planned to seek positions in a medical school on completion of their fellowships, and most preferred affiliation with a department of medical informatics or medicine.

Education, Continuing↗

Preventive care in diabetes mellitus. Current practice in urban health-care system.

Early identification and treatment of complications of diabetes mellitus may reduce the severity of the complications. As part of a program to reduce these complications in the Denver Department of Health and Hospitals patient population, our study determined how frequently preventive care, e.g., fundoscopic examinations, referral to an ophthalmologist, foot examinations, and assessment of cardiovascular risk factors, was provided to diabetic patients. With the use of billing records to identify a large sample of diabetic patients, a chart review of 544 patients was conducted. During the study year, the mean +/- SE number of visits to primary-care clinics was 5.7 +/- 0.22, with 86.4% having at least one visit. Most diabetic patients were seen by primary-care physicians; only 9% received care in a specialized diabetes clinic. Despite frequent primary-care visits, most diabetic patients in this county health-care system did not have documentation of care to detect complications of diabetes mellitus, and referral services for detection and treatment of these complications were infrequently used. Moreover, among patients seen on greater than or equal to 10 occasions in a primary-care setting, preventive care was not provided to 30% of the patients. Preventive care does not appear to be a regular part of a primary-care visit for most of the diabetic patients in this study.

Colorado↗