Biomedical subjects

T H Bartholomew

Publications and source records attributed to T H Bartholomew.

3 recordsLinked to original sources

PubMed1985

Neurogenic voiding: function and dysfunction.

Normal bladder function is dependent upon neural components for storage and coordinated, controlled evacuation. Maturation of these nervous system functions is acquired in childhood to allow a transition from the reflex voiding of infancy to the inhibitable, controlled voiding required for adult living. Alterations in this transition may manifest themselves in benign forms such as nocturnal enuresis or more severe forms that threaten urinary anatomy and function. Understanding these characteristics may involve the application of urodynamic concepts and techniques. Therapy may be chosen to counter these disturbances. This may subsequently require revision of earlier traditional approaches to recurrent cystitis and reflux.

Child↗

PubMed1979

Changing concepts in management of pelvic rhabdomyosarcoma in children.

Survival with embryonal rhabdomyosarcoma of all sites has improved dramatically in recent years with the increased use of long-term, cyclic, multidrug chemotherapy. Protocols have been established and are currently being evaluated by the Intergroup Rhabdomyosarcoma Study. The management of embryonal rhabdomyosarcoma of the pelvic viscera, though, remains troublesome. Limited surgical excision is rarely possible and high-dose radiotherapy to the bony pelvis may cause severe and disabling growth disorders. Yet, survival with these lesions is increasing as with rhabdomyosarcoma from all sites and is directly related to a well-planned and aggressive multidisciplinary program. We have seen 12 cases of pelvic rhabdomyosarcoma within the last seventeen years at this institution. These cases will be reviewed in regard to varying modes of therapy and survival. Our current therapeutic approach, based on national and local experience, will be presented.

Child↗

PubMed1978

Urologic management in cloacal dysgenesis.

Eleven cases of cloacal dysgenesis from the experience in the Baylor affiliated hospitals from 1969 to 1977 are reviewed. Clinical features including radiographic studies are presented in representative case reports. Despite the initial urgent need for intestinal surgical intervention in these patients, the long-term morbidity and complications are typically related to the genitourinary system. A review of the literature with emphasis on embryogenesis is given. Recommendations for diagnostic approach, and acute and long-term urologic management are made.

Child, Preschool↗