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Biomedical subjects

T Grumme

Publications and source records attributed to T Grumme.

At least 19 recordsLinked to original sources

Do we need ventriculography in the era of computed tomography?

The question is posed whether in the investigation of intracranial tumors, particularly in the posterior cranial fossa, CT and/or ventriculography should be practiced. We investigated 134 patients (93 were children up to the age of 14 years), all of whom had had both computed tomography and ventriculography. The results clearly demonstrate the superiority of CT compared with ventriculography. Ventriculography is a surgical intervention with risk for the patient; side effects may occur and serious complications can sometimes arise. Modern CT is producing pictures of high quality which are entirely sufficient for neurosurgical intervention. Very rarely does additional angiography have to be performed. The diagnosis of intracranial tumor can be fully established by CT and ventriculography is no longer necessary.

Adolescent

[The diagnosis of lumbar disc prolapse--computer tomographic and myelographic findings (author's transl)].

Seventy-seven patients with back pain and suspected disc prolapse were examined by computer tomography, and 41 have in addition myelograms. In 26 patients surgery was performed. The accuracy of computer tomography in the diagnosis of disc prolapse was greater than 86%, with additional myelography it was greater than 95%. Difficulties in diagnosis using computer tomography were encountered with recurrent disc prolapses. CT of the disc should be performed with a high resolution scanner using a slice thickness of 2 mm before myelography is considered. Definitely abnormal CT findings make myelography unnecessary.

Diagnosis, Differential

[Computed tomography and/or ventriculography? (author's transl)].

It is discussed if in intracranial tumors, especially in tumors of the posterior cranial fossa, a CT and/or a ventriculography should be practiced. We have made investigations of 134 patients, 93 of whom were children up to 14 years of age. Each case was undertaken computed tomography as well as ventriculography. The results are clearly demonstrating the superiority of computed tomography compared with ventriculography. Ventriculography is a surgical intervention stressing the patients, side-effects may occur, and sometimes serious complications are caused. Modern computed tomography is producing pictures of high quality, which are highly sufficient for neurosurgical intervention. Very rarely additional angiography has to be performed. The diagnosis of intracranial tumors can fully be established by computed tomography, whereas ventriculography is no longer necessary.

Adolescent

Possibilities and limitations of rehabilitation after traumatic apallic syndrome in children and adolescents.

Report on long-term follow-up studies in 23 children and 2 adolescents who survived severe brain injury and a resulting apallic syndrome. Neurological examinations and psychiatric observations were performed in all patients, and psychological tests were administered whenever possible. EEGs were recorded in all cases, and 11 patients had CT scans. 6 patients died after surviving the acute phase. 2 survived in state of stabilized unconsiousness. Recovery from the apallic syndrome was observed in 17 patients, but complete recovery did not occur in a single case. 7 patients (group A) retained severe handicaps, and the other 10 (group B) demonstrated les serious residual deficits. With a few exceptions, neurological deficit correlated with permanent psychological damage. The patients of group A presented a fairly uniform set of neurological deficits characterized by severe quadiparesis, dysarthria and other signs of permanent cerebellar dysfunction. psychological disorders included permanent aphasia (3 patients) and a major reduction on intelligence (4 patients). These patients retained a capacity for emotional response but were never able to attend school, and they remained dependent on their families or on institutions. The patients in group B demonstrated less severe permanent neurological deficits but a similar pattern of central paralysis combined with cerebellar dysfunction. These patients were able to finish their scholastic education in either a normal or special school and to work in a sheltered workshop in most cases. Only 3 patients were able to hold a job performing rather simple tasks. Duration of the initial syndrome - coma and fully developed apallic syndrome - proved to be the most significant single criterion for estimating prognosis. Rate of recovery also provided some indication of prognosis. The CT scan has proved its value in documenting localized and diffuse brain damage in later stages. We believe that CT will play an increasingly important role in establishing diagnosis as well as prognosis in the early phase.

Adolescent

CT evaluation of the CSF spaces of healthy persons.

Changes in the width of the CSF space throughout life were studied in CT scans of 170 healthy individuals. The internal and external CSF spaces were evaluated using parameters which can also be employed in routine clinical studies. Tables of normal values for the CSF spaces at various ages are presented.

Adolescent

The diagnostic value of computed tomography in orbital diseases. A cooperative study of 520 cases.

Computed tomography (CT) has given us a new method for examining the orbit and its contents. The indications for the application of computed tomography in ophthalmology are considered: suspected orbital tumors, unilateral exophthalmos, pareses of the ocular muscles, traumatic lesions and malformations in the region of the orbit. The findings in 520 cases of orbital lesions examined in this study are reported and the differential diagnosis is discussed. Considerable improvement and greater accuracy in diagnosis have been achieved in the field of ophthalmology by using computed tomography. Early tumor visualization is possible without risk or discomfort to the patient.

Cranial Nerve Neoplasms

[Assessment of brain atrophy by computer tomography (author's transl)].

Computer tomograms from 512 patients with brain atrophy were analysed according to standardized criteria. Exact studies of the outer and inner CSF spaces allowed a redefinition of this disease entity. The limits of change related to the physiological process of aging were established. In addition, an attempt was made to correlate CT findings with EEG tracings and psychiatric criteria.

Adult

Intracranial lipoma. Diagnostic and therapeutic considerations.

Eleven cases of intracranial lipoma, diagnosed during life by computerized tomography (CT) scanning, are presented. Clinical symptoms related to the lesions were present in eight. The CT scan established the diagnosis of intracranial lipoma on the basis of typical x-ray absorption and location. Only dermoid cysts and teratomas may produce a similar CT appearance. In cases of intracranial lipoma, a direct surgical approach is seldom necessary, although in certain locations, lipomas may cause blockage of cerebrospinal fluid pathways and require a shunt operation.

Adult

[Diagnostic possibilities and limitations of CT and angiography in the diagnosis of cerebro-vascular malformations (author's transl)].

The diagnosis and differential diagnosis of 891 cases of intracranial hemorrhage with rupture into the ventricles or with subarachnoid extension is discussed on the basis of CT and angiography. Both methods are complementary exams, in the indication for the study as well as in the diagnostic result. The limitations of both methods in the diagnosis of vascular malformation with and without acute hemorrhage are presented.

Brain Neoplasms

[Trauma inflicted on a baby by shaking (author's transl)].

In a baby aged 8 months the forensic post-mortem revealed injuries to the parasagittal pontine veins without visible evidence of traumatic violence. The mother later admitted to having grabbed the baby laterally by the chest and shaken it. This had resulted in an angular acceleration of the head about a transversal axis and, by the lag of the brain due to its inertia, in the fatal vascular lesions mentioned. The twin child admitted to hospital with comparable signs rapidly developed via an acute hygroma a generalized cerebral atrophy such as is actually to be expected in senescence only.

Autopsy