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Biomedical subjects

T Griffin

Publications and source records attributed to T Griffin.

81 records · Page 5Linked to original sources
PubMed1977

Are pelvic irradiation and routine staging laparotomy necessary in clinically staged IA and IIA Hodgkin's disease?

Thirty-nine patients with clinically staged IA and IIA Hodgkin's disease were treated with mantle plus paraaortic/splenic irradiation between 1968 and 1975. All patients had supradiaphragmatic presentations, and none had staging laparotomies. With a follow-up time of 1 to 9 years, mean 4.3 years, the overall relapse-free survival is 92% (100% for stage IA and 89% for stage IIA). The absolute relapse-free 5-year survival is 91% There were no pelvic recurrences. These data show that routine staging laparotomy and pelvic irradiation are not indicated for clinically staged IA and IIA Hodgkin's disease with supradiaphragmatic presentation. The criteria for staging laparotomy in early-stage Hodgkin's disease are discussed.

Adolescent↗
PubMed1977

Effect of local irradiation on the acute rejection process in transplanted kidneys.

The graft in 178 renal transplant patients was irradiated in an effort to halt acute rejection phenomena. Of the patients, 61 per cent received their transplant from either a sibling, parent or child and 38 per cent received cadaveric kidneys. Of the irradiated kidneys 61 per cent were functioning at 6 months, 58 per cent at 12 months and 49 per cent at 18 months. The rational for irradiation of transplanted kidneys with acute rejection is discussed.

Adolescent↗
PubMedDate not supplied

Parental evaluation of a tour of the neonatal intensive care unit during a high-risk pregnancy.

OBJECTIVE: To describe parents' reaction to a prenatal tour of the neonatal intensive care unit (NICU) during a high-risk pregnancy and identify advice they have for other parents and health care professionals who participate in a such a tour. DESIGN: Naturalistic inquiry, a qualitative approach. SETTING: Semistructured interviews were conducted in the hospital or parents' home. PARTICIPANTS: Thirteen expectant parents who had toured a NICU during a high-risk pregnancy. MAIN OUTCOME MEASURES: Three categories of information were described by the parents: (a) a description of the tour; (b) benefits of the tour; and (c) an evaluation of the way that the tour was arranged and conducted, including advice to health care professionals and other parents. RESULTS: All parents recommended that parents diagnosed with a high-risk pregnancy be offered a prenatal tour of the NICU. The tour benefited parents and (a) decreased fears, (b) inspired hope for the infant's prognosis, (c) provided reassurance about the care in the NICU, and (d) prepared parents for their infant's hospitalization in the NICU. CONCLUSIONS: Parents experiencing a high-risk pregnancy benefit from a tour of the NICU. The tour familiarized parents with the NICU and the type of care that their newborn would require. However, during the tour, more attention should be given to the parental role in the NICU.

Adaptation, Psychological↗
PubMedDate not supplied

Pediatric traumatic atlanto-occipital dislocation: five cases and a review.

Traumatic atlanto-occipital dislocation (AOD) has been thought to be a rare and fatal injury. Recently, more survivors, especially children, have been reported. During a 10-year period, the authors have encountered five children with traumatic AOD. A retrospective review of traumatic AOD in children from 1985 to 1995 was performed. Clinical presentation, initial radiologic findings, and final outcome were emphasized. Distance from the dens to the basion and the ratio of Powers were measured from initial lateral cervical spine radiographs. The average distance from the dens to the basion was 9.8 mm. The average ratio of Powers was 1.38. There were three survivors, two having a concomitant spinal cord injury. All survivors underwent a posterior occipitovertebral fusion. Three cases initially went undiagnosed. The diagnosis of AOD by lateral cervical spine radiographs can be difficult. The authors recommend detailed measurements of the initial cervical spine radiographs in pediatric patients at risk for traumatic AOD.

Atlanto-Occipital Joint↗