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Biomedical subjects

T Goto

Publications and source records attributed to T Goto.

At least 937 records · Page 52Linked to original sources
PubMed1975

Spectral characteristics of the bioluminescence induced in the marine fish, Porichthys notatus by Cypridina (ostracod) luciferin.

Specimens of Porichthys notatus, which are naturally luminous along the coast of California, are non-luminous in Puget Sound. However, luminescence capability may be induced in the adult Puget Sound Porichthys by the administration of purified Cypridina (ostracod) luciferin, synthetic Cypridina luciferin, or Cypridina organisms. The bioluminescence emission spectra produced by the Puget Sound fish following induction is similar, if not identical, to that of the naturally luminous Porichthys notatus from California waters (maxima: 485 and 507 nm).

Animals↗
PubMed1975

A new flavin enzyme catalyzing the reduction of dihydrodipicolinate in sporulating Bacillus subtilis. II. Kinetics and regulatory function.

Dihydrodipicolinate reductase in Bacillus subtilis PCI 219 had FMN as a prosthetic group, and the hydrogen transfer pathway is considered to be NADPH yields FMN yields dihydrodipicolinate. Linewaver-Burk plots of the reciprocal of the activity against the reciprocal of the concentration of either of the two substrates, dihydrodipocolinate and NADPH, are consistent with a reaction mechanism involving interconversion of two free forms of the enzyme by the two substrates. The Km values obtained from the secondary plots are 0.77 mM for dihydrodipicolinate and 72 muM for NADPH. Inhibition by dipicolinate is competitive with NADPH and noncompetitive with dihydrodipicolinate, and shows positive cooperativity. The possible metabolic role of the reductase in sporulating Bacillus subtilis is discussed in connection with regulation of the biosyntheses of dipicolinate and diaminopimelate.

Anaerobiosis↗