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T Gislason

Publications and source records attributed to T Gislason.

65 records · Page 4Linked to original sources

Snoring and systemic hypertension--an epidemiological study.

The prevalence of snoring, overweight and systemic hypertension was estimated in a random sample of 4,064 Swedish men, aged 30-69 years. Of the responders, 15.5% complained of habitual snoring and 29.6% of occasional snoring. Although there was an age-related increase in the prevalence of snoring up to 60 years, habitual snoring was found to be mainly related to body mass index (BMI) (p less than 0.0001) but not to age. Altogether 299 men (9.3%) reported hypertension, 21.5% of whom were habitual snorers, compared with 14.9% of the non-hypertensives (p less than 0.01). The hypertensives were also more often overweight. Logistic multiple regression analyses showed that among subjects 40-49 years old there was an average increase in the predicted prevalence of hypertension from 6.5% among non-snorers to 10.5% of habitual snorers in the same weight group. For the whole study population, however, the increase was mainly dependent on age and BMI. Thus, the importance of habitual snoring for the prevalence of hypertension differs in various age groups.

Adult↗

Prevalence of sleep apnea syndrome--estimation by two stage sampling.

This article describes stepwise the methodological and statistical considerations made in the planning of an epidemiological survey of the prevalence of the sleep apnea syndrome (SAS) in the municipality of Uppsala in Sweden. The investigation had to be confined to 60 subjects, since all-night polysomnographic studies are required for an unequivocal diagnosis of SAS. It was decided to investigate men 30 to 69 years old. Initially, the possibility of taking a simple random sample (SRS) was considered, but statistical calculations showed that for prevalences between 1-3% this would lead to totally unacceptable results. A postal questionnaire, sent to the total population of 35,779 men in this age group, was then considered and, depending on their replies, they would be divided into low-risk and high-risk stratums of SAS. Optimal numbers would then be called from each group for polysomnographic studies. This also proved impossible, as the lowest possible standard error was still too large and the samples would contain unacceptably few cases of SAS. We therefore decided to concentrate on the highrisk stratum, obtaining an estimated under limit of the prevalence. For economical reasons, we could not send a questionnaire to all the 35,779 individuals, but based the investigation on a SRS of 4,000 men, post-stratified in a high-risk and a low-risk group. From the high-risk group, 60 men were then selected for polysomnographic studies.

Humans↗

Somatic diseases and sleep complaints. An epidemiological study of 3,201 Swedish men.

The prevalence of sleep complaints and somatic diseases was estimated in a random sample of 4064 Swedish men aged 30-69 years. Great difficulty initiating sleep (DIS) was experienced by 6.9% and moderate problems in DIS by 14.3%. Complaints of major difficulty maintaining sleep (DMS) were reported by 7.5% of the men and of moderate DMS by 14.9%. DMS was more frequent with increasing age. Excessive daytime sleepiness (EDS) was reported by 5.7%. Altogether 879 men were attending regular medical examinations for somatic diseases. Among the 299 hypertensive men, major complaints of DMS (13.5%), DIS (8.4%) and EDS (8.8%) were more common, but the 167 men treated with beta-blockers rather showed a proportionally somewhat lower prevalence of sleep complaints. Men with obstructive pulmonary disease (n = 113) had a higher prevalence of DMS (18.8%) and EDS (12.4%). Diabetic men (n = 74) complained also more often of DMS (21.9%), DIS (21.1%) and EDS (12.2%). Men with rheumatic disease (n = 176) and obesity (n = 221) also had increased prevalence of sleep complaints.

Adult↗

Serum calcium in bronchial carcinoma: a population-based study.

Serum calcium (s-Ca) was measured in 245 patients with bronchial carcinoma. Mean s-Ca (+/- SD) was 2.52 +/- 0.14 mmol/l in the cancer patients, compared to 2.48 +/- 0.14 mmol/l in a control group (p less than 0.01). Sixty-one (25%) of the patients with bronchial carcinoma had hypercalcaemia (s-Ca greater than or equal to 2.60 mmol/l), compared to 16% of the controls. Squamous cell carcinoma was the histological type most often associated with hypercalcaemia. Patients with hypercalcaemia were not overrepresented among those with bone metastases. During follow-up another 32 patients developed hypercalcaemia. Altogether 93 patients (38%) became hypercalcaemic at some time in the course of the disease. In 20 patients s-Ca fell below 2.60 mmol/l after radiotherapy, after operation, or spontaneously. The survival time was significantly shorter for patients with s-Ca above 2.68 mmol/l on admission than for those with s-Ca below this value.

Adult↗

Sedimentation rate, leucocytes, platelet count and haemoglobin in bronchial carcinoma: an epidemiological study.

Erythrocyte sedimentation rate (ESR), leucocyte count, platelet count, haemoglobin concentration (Hb) and survival were studied in an epidemiological material of 258 patients with bronchial carcinoma. The mean ESR was elevated (48.1 mm/h) and, more so in squamous cell and small cell carcinoma than in large cell and adenocarcinoma. Leucocytosis, over 9 X 10(9)/l, was found in 39% of the patients and thrombocytosis, over 400 X 10(9)/l, in 13% of the patients. Nine per cent of the patients were anaemic, with Hb lower than 11 g/l. There was a statistically significant positive correlation between ESR, leucocyte count and platelet count, but a negative correlation was found between these 3 variables and Hb. ESR, leucocyte count and platelet count also correlated to survival at a statistically significant level. Multiple regression analysis of these laboratory variables showed that they explain about 8% of the great variations in survival time.

Adenocarcinoma↗

Primary ureteral leiomyosarcoma.

Primary leiomyosarcoma is a rare tumor of the ureter. Including the two patients here presented, only 14 cases have been reported. Both of our patients also had other, unrelated malignancies.

Aged↗

Aggressive management of bilateral renal cell carcinoma.

We review 4 cases of bilateral renal cell carcinoma. Treatment included extracorporeal surgery with subsequent autotransplantation in 2 patients and radical nephrectomy combined with contralateral partial nephrectomy in the remaining 2 patients. Absence of recurrence as well as length of patient survival supports this aggressive therapy.

Adenocarcinoma↗

Acute epididymitis in boys: a 5-year retrospective study.

A retrospective study was undertaken of 25 children with epididymitis seen at our pediatric hospital during the last 5 years. The symptoms and signs in these patients were evaluated, as well as the results of urinalysis, urine culture, excretory urogram, scrotal scan, exploration and white blood count. The presence of underlying urological problems was particularly sought for and found to be rare prior to epididymitis. The treatment and results are reviewed.

Acute Disease↗

Computed tomography of the oropharynx in obstructive sleep apnea.

Uvulopalatopharyngoplasty (UPPP) is currently the preferred method for treatment of the obstructive sleep apnea syndrome (OSAS). However, only 50 per cent of the patients operated upon are cured by this surgical procedure, and there is a demand for better and more objective selection criteria. Computed tomography (CT) of the oropharynx was obtained in 32 consecutive adult patients with proven OSAS. An additional 15 patients with the same complaints, but without objective evidence of OSAS, were used as a control group, together with 20 normal subjects. The axial widths of the tongue and the genioglossus and hyoglossus muscles were measured by CT. Both the tongue and genioglossus widths were significantly larger in the OSAS patients than in the two control groups (p less than 0.001). The increased tongue width will cause encroachment of the oropharyngeal airway below the level of the soft palate. Thus, CT can be used to measure the tongue size in order to evaluate its predictive value for the outcome of the UPPP procedure.

Adult↗