Search PubMedSearch

Biomedical subjects

T Gerner

Publications and source records attributed to T Gerner.

42 records · Page 3Linked to original sources

The heterogeneity of the serum activity of gamma-glutamyl transpeptidase in hepatobiliary diseases as studied by agarose gel electrophoresis.

Using electrophoresis on agarose gel, the serum activity of gamma-GT in various hepatobiliary diseases has been separated into several electrophoretic fractions. Predominance of activity was always found in fractions corresponding to either alpha1-, alpha2- or beta-globulins. The predominant activity fractions have been related to the various disease states and to the zymogram patterns of gamma-GT found in bile and tissue homogenates of liver, bile duct and pancreas. Bile disclosed activity in the beta-region, tissue homogenates of liver mostly in the alpha1- and alpha2- areas, bile dict showed very faint activity in the alpha1- position, while extracts of pancreas revealed activity in the regions of alpha2, alpha2-beta and beta-gamma. In serum, dominance of alpha1-activity was found in all cases associated with alcoholism and alcoholic cirrhosis, this activity also appeared as the most frequent dominant one in biliary obstruction. Predominance of alpha2 and/or the beta-fraction in most cases occurred associated with malignant processes involving liver and/or pancreas.

Alcoholism

Persistent sciatic artery. Case report.

In a man with ischemia of the right leg due to embolism of popliteal artery, arteriography following failure of embolectomy via the common femoral artery revealed the internal iliac artery continuing as an aneurysmally dilated sciatic artery distally to the popliteal artery. The aneurysm was ligated and bypass established from the common femoral to the popliteal artery.

Aneurysm