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Biomedical subjects

T Gergely

Publications and source records attributed to T Gergely.

18 recordsLinked to original sources

A computer system for interpreting blood glucose data.

This paper presents an overview on the design and implementation of a computer system for the interpretation of home monitoring data of diabetic patients. The comprehensive methodology covers the major information processing steps leading from raw data to a concise summary of what has happened between two subsequent visits. It includes techniques for summarising and interpreting data, checking for inconsistency, identifying and diagnosing metabolic problems and learning from patient data. Data interpretation focuses on extracting trend patterns and classifying/clustering daily blood glucose (BG) profiles. The software helps clinicians to explore data recorded before the main meals and bedtime, and to identify problems in the patient's metabolic control which should be addressed either by educating the patient and/or adjusting the current management regimen.

Blood Glucose↗

[Jews and physicians].

The purpose of this paper is to examine the well established yet hardly explored connections between the Jews and the field of medicine. In other words, it is our intention to inquire into the reasons, sometimes historical and social, sometimes cultural and religious - or all of these at the same time - which have led and maybe still lead - such vast numbers of Jews to embark upon a course of study in medicine. Reasons which might be closely linked with their traditional perception of the figure of the father, of the rabbi, maybe even of God.

History, Ancient↗

Dynamic optical imaging.

The main direction in modern imaging is increasing the spatial resolution and selectivity for pathology pattern recognition at the microscale. Dynamic optical imaging (DOl) has enormous potential in the selectivity of description of living tissue state at cellular and subcellular levels. However, multiple light scattering creates considerable difficulties in revealing the tissue microstructure in its depth. On the other hand, along with changes in the microstructure, pathology should also manifest itself in the integral macroscopic pattern of the tissue. Actually, living tissue, as a distributed active media with well-developed reception and self-regulation, is characterized by a high spatial synergy. In such a media, even morphologically small pathology could disturb tissue functioning in a rather extended area. As a result, after some definite time, a diffuse "field" of the pathological phenomena appears even in the morphological image. Since optical contrast is determined by tissue components (such as blood), which actively participate in physiological functioning, the distributed functional pattern of the tissue is reflected in optical images in the form of spatiotemporal modulation of the optical density. This observation opens up the possibility of investigating the diffuse pattern of the pathology at the functional stage of its development, even before the actual appearance of noticeable morphological changes .

Journal Article↗

[The value of laboratory tests (author's transl)].

The diagnostic significance of various laboratory tests was studied at a Medical University Clinic and a regional hospital. Requests for such tests were graded on admission according to the criteria: (a) necessary for differential diagnostic decision; (b) part of routine admission programme. Results were assessed according to the criteria: (a) clinical "proof"; (b) of value in differential diagnosis; (c) pointing to another diagnosis; (d) unhelpful. Analysis of the results provided an interesting agreement: all doctors graded seven to ten tests as necessary. Those with the highest information content were the classical tests--erythrocyte sedimentation rate, serum-electrophoresis and blood sugar levels. 45.6% of those graded as necessary proved informative; 7.2% of routinely ordered tests provided pointers to another diagnosis. This percentage is the contribution of laboratory tests beyond what doctors consider as necessary for diagnosis. This additional value of laboratory tests is relatively high so that a reasonably extensive programme of laboratory tests on admission appears justified, especially if one adds the time factor to cost-effectiveness.

Blood Glucose↗

[Results of screening for diabetes within the health-care program of vienna (author's transl)].

Within the health-care program of Vienna 1577 volunteers (1203 female, 374 male persons) were screened for diabetes mellitus during 1975/76. Besides measurement of glucose tolerance one hour after the ingestion of 100 g glucose the following parameters were analyzed: cholesterol, triglycerides, uric acid and blood pressure. Male persons had a slightly decreased glucose tolerance; a distinct relationship with age was found in both sexes. After elimination of volunteers in whom pathological results were obtained with respect to other examined parameters, a significantly greater glucose tolerance was found in the remaining "normal" group. There are no parameters which are closely correlated with glucose tolerance although it was possible to reject the null-hypothesis in several cases due to the large sample involved. For statistical reasons (test sensitivity, test specificity, prevalence of disease) single glucose-tolerance measurements do not give enough evidence for diagnosing diabetes mellitus. Depending on the aims of the screening program one has to define the detection limits as well as frequency of retesting.

Adolescent↗

[A comparison of serum phosphohexose isomerase and sialyl transferase activities in patients with malignant disease].

The diagnostic value of serum sialyl transferase, phosphohexose isomerase and lactate dehydrogenase determinations is discussed in respect to patients with malignant diseases. It was found that 80 % of the investigated cases showed an increase in serum sialyl transferase activity. Phosphohexose isomerase was elevated in 46.6 % and lactate dehydrogenase in 23.3% of the cases. The serum sialyl transferase activity was within the normal range in 13.3% of the patients. It is concluded that although the serum sialyl transferase activity is of great diagnostic significance in cases of suspected malignancy, total reliance cannot be placed on the determination of this sole parameter, but only in conjunction with others.

Breast Neoplasms↗

[X-ray documentation of the anamnesis and physical data in patients with rheumatism within the scope of the medical information system WAMIS].

A computerized on-line system of evaluating of symptoms and physical data in rheumatology is presented. Case history, previous treatment, and physical examination are documented. The documentation of the latter may be performed in two ways: one records only joint symptoms, the other includes joint measurements. In comparison to the former off-line method, all data are much better available. Moreover, we believe it to be considerably timesaving. This system should also allow an electronic differential diagnosis of rheumatic diseases, after completing laboratry and X-ray documentation.

Austria↗