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Biomedical subjects

T G Parks

Publications and source records attributed to T G Parks.

108 records · Page 6Linked to original sources
PubMed1970

Rectal and colonic studies after resection of the sigmoid for diverticular disease.

Spontaneous basal rectal activity, recorded after resection of the sigmoid colon for diverticular disease, was more than twice the normal. The rectum of post-resection cases yielded a markedly exaggerated overall response to prostigmine, in addition to producing abundant fast wave patterns. The response to stretch of the apparently normal colonic muscle remaining after resection of the sigmoid for diverticular disease resembled unresected diverticular segments, though less in degree, suggesting that a fundamental disorder of colonic muscle may be involved in the aetiology of colonic diverticula.

Colon↗
PubMed1970

Familial polyposis coli associated with extracolonic abnormalities.

The pedigree of a polyposis coli family, in which several individuals had extracolonic abnormalities associated with the condition, is presented. Some of the problems encountered in management are discussed. The literature is reviewed and a simple classification of the extracolonic abnormalities is suggested.

Abdominal Neoplasms↗
PubMed1969

Natural history of diverticular disease of the colon. A review of 521 cases.

In a survey of the natural history of 521 patients with diverticular disease of the colon half of the patients had had symptoms for less than one month on presentation at hospital, and these carried the highest morbidity and mortality. Progression of the disease was usually within segments initially involved, and extension to other regions of the colon rarely occurred. The overall prognosis of patients with total colonic involvement was similar to those with localized disease, while the morbidity and mortality associated with a recurrent attack were higher than in the initial acute episode.

Adult↗
PubMed1969

Reappraisal of clinical features of diverticular disease of the colon.

In patients with diverticular disease of the colon factors which indicate a worse prognosis include widespread abdominal pain, nausea and vomiting, disturbed bowel habit, a palpable abdominal mass, abdominal distension, and any of the inflammatory complications. While radiology is of prime importance in the initial diagnosis, it is often impossible to differentiate between diverticulosis and diverticulitis. A more accurate distinction can be made by assessing all the available clinical, radiological, and pathological data, but again there are limitations and inaccuracies. The use of the term "diverticular disease" is preferable.

Abdomen↗
PubMedDate not supplied

The usefulness of tests in anorectal disease.

Specialized tests of anorectal function are designed to complement but not to replace good clinical examination and sound professional judgement. The different methods of recording pressure changes have advantages and disadvantages. Poor correlation exists when data recorded using miniature balloons are compared with data from microtransducers. Prolonged ambulatory monitoring of anal sphincter and rectal pressure reveal that spontaneous transient episodes of sphincter relaxation are demonstrable in normal subjects. In the investigation of patients with possible traction injury to the pudendal nerve, electromyography and pudendal nerve terminal motor latency data are more precise than manometry data. Good correlation between noninvasive surface electromyography using an intra-anal plug electrode and anal manometry can be attained. Mapping of sphincter defects using concentric needle technology is reasonably accurate but distinctly painful. Dynamic defecography readily demonstrates abnormalities of the rectal wall. The division between what is normal and what is clinically relevant is rather imprecise. Comparative studies of sonographic and electromyographic mapping of sphincter defects give good correlation. Recent application of fine hooked electrodes have demonstrated periodic episodes of smooth muscle and sphincter relaxation. The saline infusion test and balloon expulsion test help to accurately quantify the difficulty patients experience in retention or evacuation, respectively. Perineometry is a simple, rapid, noninvasive method of measuring the extent of perineal descent on straining. Although reproducible, it tends to underestimate the degree of descent when compared with the radiological method but it avoids the use of ionized radiation.

Anus Diseases↗