Search PubMed⌕ Search

Biomedical subjects

T G Lohman

Publications and source records attributed to T G Lohman.

At least 37 records · Page 2Linked to original sources
PubMed1997

Fat or lean tissue mass: which one is the major determinant of bone mineral mass in healthy postmenopausal women?

The relative importance of fat and lean tissue mass in determining bone mineral mass among postmenopausal women was examined in this 1-year longitudinal study. Fifty postmenopausal Caucasian women entered the study; 45 of them completed a 1-year follow-up. Dual-energy X-ray absorptiometry was employed for measuring total and regional bone mineral density (BMD) and bone mineral content (BMC), fat tissue mass (FTM), lean tissue mass (LTM), and body weight. Results from linear regression analysis using the cross-sectional data (n = 50) of the study indicated that LTM explained a larger percentage of variation in bone mineral mass than did FTM. FTM and LTM were found to be moderately correlated (r = 0.55); when FTM was entered in the same predicting regression models, LTM was a significant predictor (p < 0.05) of the total and regional BMC, but not BMD. The percent FTM (and inversely %LTM) was correlated with BMD and BMC, but significant correlation was primarily found only for total body BMD (or BMC). Weight was the best predictor of total body BMD and BMC. Longitudinally (n = 45), annual changes in both FTM and weight were significantly associated with annual changes in regional BMD after adjustment for initial bone mineral values (p < 0.05). We conclude that bone mineral mass is more closely related to LTM than to FTM, while annual changes in regional BMD are more closely correlated with changes in FTM in healthy postmenopausal women. Meanwhile, increased body weight is significantly associated with increased bone mineral mass.

Absorptiometry, Photon↗
PubMed1996

Why bioelectrical impedance analysis should be used for estimating adiposity.

The whole-body bioelectrical impedance analysis (BIA) approach for estimating adiposity and body fat is based on empirical relations established by many investigators. Properly used, this noninvasive body-composition assessment approach can quickly, easily, and relatively inexpensively provide accurate and reliable estimates of fat-free mass (FFM) and total body water (TBW) in healthy populations. The estimated FFM or TBW values are used to calculate absolute and relative body fat amounts. When different investigators follow the same standard BIA procedures and use the same population and criterion method, similar prediction equations and relatively small prediction errors have been reported for measurement of FFM and TBW (SEE: 1.7-3.0 for FFM and 0.23-1.5 kg for TBW). The BIA approach is most appropriate for estimating adiposity of groups in epidemiologic and field studies but has limited accuracy for estimating body composition in individuals. When used as a simple index (stature2/ resistance), BIA is more sensitive and specific for grading average adiposity in groups than some other anthropometric indexes such as the body mass index. Prediction equations based on BIA have been validated and cross-validated in children, youths, adults, and the elderly, in primarily white populations and, to a limited extent, in Asian, black, and Native American populations.

Adipose Tissue↗
PubMed1996

Effects of variations in regional composition on soft tissue measurements by dual-energy X-ray absorptiometry.

OBJECTIVE: To assess the effect of variations in regional composition on the accuracy of dual-energy X-ray absorptiometry (DXA) in humans by placing packets of lard, water and ground beef, to simulate fat, very lean tissue and high density lean material, on the thighs and abdomen. SUBJECTS: 28 healthy males and females (mean age: 25 y; mean % fat: 24.6%). METHODS: Up to six consecutive total body DXA scans (baseline plus five scans with added packets) at 16 cm/s were performed on each subject (Lunar DPX-L, software version 1.3y). Eight conditions were examined: one lard packet (n = 18), two stacked lard packets, one ground beef packet and one water packet (all n = 10) alternately placed on the thighs and abdomen. Masses (kg) and percentage fats (% fat) of the lard, water and ground beef packets were 1.45 and 90%, 2.80 and 4% and 1.80 and 24%, respectively. RESULTS: Differences between actual (baseline plus packet) and measured composition were assessed using paired t-tests (p < 0.05). Under all conditions except with two abdominal lard packets, actual and measured total mass were similar (p > 0.05). Percentage fat of one lard packet was significantly underestimated when placed on the abdomen (90% actual vs 52% measured). The % fat of two lard packets was underestimated when placed on the thighs (90% vs 77%) and abdomen (90% vs 47%) while the % fat of the water packet was overestimated in both locations. CONCLUSION: The Lunar DXA underestimates the % fat of lard placed over the abdomen moreso than when placed over the thighs and overestimates % fat of water in both locations independent of thickness. Ground beef is accurately detected.

Abdomen↗
PubMed1995

Nutrients, body composition and exercise are related to change in bone mineral density in premenopausal women.

This study determined relationships among total energy intake, nutrient intake, body composition, exercise group status, and annual rates of change (slopes) in bone mineral density in 66 Caucasian premenopausal women (mean age, 34.4 +/- 2.7) taking calcium supplements. Body composition components measured by dual-energy X-ray absorptiometry included fat mass, soft tissue lean mass, and bone mineral density (g/cm2) of total body, spine (lumbar vertebrae 2-4), and three femur sites measured at baseline, 5, 12, and 18 mo. Nutrients were not significant variables in regression models predicting bone mineral density slopes (rates of change) at any femur site. The only significant variable in models predicting Ward's triangle bone mineral density slope was the initial fat mass and, for trochanter, exercise. Significant variables (P < 0.05) in models predicting total body bone mineral density slope included the initial fat mass and fat mass slope plus either vitamin A, carotene, fiber, magnesium, or phosphorus (R2 from 0.31 to 0.25) and fat mass slope plus sodium (R2 = 0.24). The significant variable in the model predicting L2-4 slope was energy intake (R2 = 0.17, P < 0.05). We conclude that nutrient intake, exercise, and body composition are related to bone mineral density rate of change and that relations among these variables vary by bone site.

Absorptiometry, Photon↗
PubMed1995

Practical techniques for assessing body composition in middle-aged and older adults.

The purpose of this study was to compare the relationships of anthropometric, bioelectrical impedance analysis (BIA), and near infrared interactance (NIR) measurements with a multiple-component (MC) criterion estimate of body composition derived from body density (D), body water (W), and bone mineral (B) in 48 white adults aged 49-80 yr. Relative errors of predicting the MC criterion from the practical measurements were determined by simple regressions within gender and calculated as the SEE divided by the criterion mean and expressed as a percentage. Relative errors were lowest for the BIA variable, height2/resistance (4.8-5.0%), higher for body mass index and the sum of 10 skinfold thicknesses (7.0-14.5%), and highest for NIR-derived optical density readings at the biceps and the sum of 10 sites (10.8-15.8%). Due to the low relative prediction error for height2/resistance, sex-specific BIA formulas for estimating fat-free mass from D, W, and B (FFM-DWB) were developed. The SEEs for predicting FFM-DWB from BIA, weight, and age were both 1.5 kg in women and men. Because BIA is not limited to ambulatory subjects, it is concluded that BIA may be a particularly useful, practical technique for estimating body composition in older adults.

Aged↗
PubMed1993

Resistance exercise training is associated with decreases in serum low-density lipoprotein cholesterol levels in premenopausal women.

BACKGROUND: Aerobic exercise training is associated with reduced serum concentrations of triglycerides, increased concentrations of high-density lipoprotein cholesterol, and minimal changes in serum levels of total cholesterol or low-density lipoprotein cholesterol. There are few data on the effects of resistance exercise on blood lipid levels. METHODS: Premenopausal women were randomly assigned to a supervised resistance exercise training program (n = 46) or a control group (n = 42) for 5 months. Serum was analyzed for levels of total cholesterol, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, and triglycerides. Body composition and dietary intake were also measured. RESULTS: The exercise group showed a 0.33 +/- 0.03-mmol/L (mean +/- SE) decrease in total cholesterol level and a 0.36 +/- 0.001-mmol/L decrease in low-density lipoprotein cholesterol level that was significantly different from the control group. No significant changes were noted in serum high-density lipoprotein cholesterol or triglyceride levels in either group. Changes in body composition showed no significant correlations with changes in total cholesterol or low-density lipoprotein cholesterol. There were no significant differences in nutrient intake between the groups. CONCLUSION: In healthy, premenopausal women, with normal baseline lipid profiles, 5 months of resistance exercise training was associated with significant decreases in serum total cholesterol and low-density lipoprotein cholesterol concentrations.

Adult↗
PubMed1993

Multicomponent models in body composition research: opportunities and pitfalls.

This paper presents theoretical, methodological, and statistical considerations in the evaluation of multicomponent body composition models. The opportunities for multicomponent approaches to validate new body composition methods, to provide definitive references for FFB composition values of different populations, and to evaluate changes in various components of the body with age and interventions are well-recognized. The pitfalls of the multicomponent approach, however, limit the success of past research efforts. If future investigations evaluate in the same study design the theoretical, methodological and statistical approaches presented, improved multicomponent approaches will be developed, and present controversies surrounding the variability in composition of FFB as well as the validity of new methodologies such as DXA will be resolved.

Adipose Tissue↗
PubMed1993

Detection of small changes in body composition by dual-energy x-ray absorptiometry.

The ability of dual-energy x-ray absorptiometry (DEXA) to detect small changes in body composition was studied in 17 men and women during a dehydration-rehydration protocol. Scale weight (BW) and total mass (TM) from DEXA were highly related (r > 0.99) as were estimates of fat-free mass (r = 0.99) and percent fat (r = 0.97) from DEXA and densitometry. Changes in BW of approximately 1.5 kg due to fluid loss and gain were highly correlated (r = 0.90) with both changes in TM and soft-tissue mass (STM) by DEXA but less so (r = 0.67) with changes in lean-tissue mass (LTM). Mean changes in TM, STM, and LTM were not different (P > 0.05) from changes in BW. Estimates of bone mass and fat were unaffected by changes in hydration. We conclude that DEXA is able to detect small individual changes in TM and STM and is also useful for detecting group changes in LTM.

Absorptiometry, Photon↗
PubMed1993

Hydration of the fat-free body mass in children and adults: implications for body composition assessment.

Previous studies have shown that children have a higher aqueous fraction of the fat-free body mass (FFM) than young adults. In older adults, methodological differences among studies limit evaluation of potential age-related differences in the water content of the FFM (W/FFM). Therefore, we determined W/FFM in 28 healthy white prepubescent children (age = 5-10 yr), 31 young adults (age = 22-39 yr), and 62 older adults (age = 65-84 yr), using 2H2O dilution to estimate total body water and a multicomponent approach based on body density, total body water, and regional bone mineral density to estimate FFM. To quantify the extent to which variation in W/FFM affects percent fat estimation error, differences in percent fat between our multicomponent approach and the Siri two-component model were related to W/FFM. Prepubescent children (72.7 +/- 1.6%) and older adults (72.5 +/- 1.4%) were found to have significantly higher (P < 0.01) mean W/FFM than young adults (70.8 +/- 1.2%). Differences in percent fat between the multicomponent and two-component models ranged from -10 to 6% fat and were significantly associated with W/FFM (r = -0.62, P < 0.0001). We conclude that prepubescent children and older adults, on average, have a higher W/FFM than young adults, and that, in adults, individual differences in W/FFM account for a substantial portion of the percent fat estimation errors associated with the use of two-component body composition models.

Adipose Tissue↗
PubMed1993

Prediction of body composition in premenopausal females from dual-energy X-ray absorptiometry.

Four methods for predicting body composition were compared in premenopausal females (n = 100), 28-39 yr old, by using underwater weighing (UWW) as the criterion method. The four methods were dual energy X-ray absorptiometry (DEXA), skinfolds, bioelectrical impedance, and body mass index. The sample had a mean percent fat (%fat) of 29.7 +/- 6.8% (SD) by DEXA and 29.9 +/- 5.8% measured by UWW. DEXA yielded a standard error of estimate (SE) of 2.4% (r = 0.91) for the prediction of %fat from UWW. When %fat was estimated from other methods, larger SEs were obtained: 3.0% for skin-folds, 3.3% for body mass index, and 2.9% for bioelectrical impedance (height2/resistance) plus weight. Individual body density values derived from UWW were corrected for bone mineral variation. DEXA predicted the corrected body density with a lower SE (0.0040 vs. 0.0053 g/ml) than the original density values. We conclude that DEXA was a precise method and correlated highly with fat-free body weight and %fat from UWW in this homogeneous female sample.

Absorptiometry, Photon↗
PubMed1993

Relationship of body fat percentage and fat distribution with dehydroepiandrosterone sulfate in premenopausal females.

Dehydroepiandrosterone (DHEA) has an antiobesity effect in rodents, and elevated endogenous levels of its sulfate ester (DHEAS) are associated with reductions in risk for cardiovascular disease (CVD) in men. To examine the association of body fat and fat distribution, established correlates of CVD and CVD risk factors, with circulating DHEAS levels in women, we measured trunk and limb skinfold thicknesses and circumferences, total and regional body fat from dual energy x-ray absorptiometry (DXA), and serum levels of DHEAS in 96 healthy Caucasian females aged 28-39 yr. Body mass index, percentage fat from DXA and the waist-to-hip ratio were not significantly correlated (r < or = 0.15, P > or = 0.156) with serum DHEAS levels, regardless of statistical control for age, smoking behavior, and fasting status. However, the ratio of trunk/total skinfold thicknesses (r = 0.23, P = 0.030) and the percentage of total fat located on the trunk from DXA (r = 0.32, P = 0.002) were positively correlated with DHEAS, whereas the ratio of leg/total skinfold thicknesses (r = -0.25, P = 0.015) and the percentage of total fat located on the legs from DXA (r = -0.25, P = 0.015) were inversely correlated with DHEAS after adjusting for age, smoking, and fasting status. With the exception of the trunk/total skinfold thickness ratio, the correlations of DXA- and skinfold-derived estimates of fat distribution remained significant (P < or = 0.033) even after further adjustment for percentage fat or body mass index. It is concluded that increased amounts of total fat located on the trunk and decreased amounts of total fat located on the legs are associated with increased serum DHEAS concentrations in normally menstruating females.

Adipose Tissue↗
PubMed1992

Bioelectrical impedance estimation of fat-free body mass in children and youth: a cross-validation study.

The purposes of this study were to develop and cross-validate the "best" prediction equations for estimating fat-free body mass (FFB) from bioelectrical impedance in children and youth. Predictor variables included height2/resistance (RI) and RI with anthropometric data. FFB was determined from body density (underwater weighing) and body water (deuterium dilution) (FFB-DW) and from age-corrected density equations, which account for variations in FFB water and bone content. Prediction equations were developed using multiple regression analyses in the validation sample (n = 94) and cross-validated in three other samples (n = 131). R2 and standard error of the estimate (SEE) values ranged from 0.80 to 0.95 and 1.3 to 3.7 kg, respectively. The four samples were then combined to develop a recommended equation for estimating FFB from three regression models. R2 and SEE values and coefficients of variation from these regression equations ranged from 0.91 to 0.95, 2.1 to 2.9 kg, and 5.1 to 7.0%, respectively. As a result of all cross-validation analyses, we recommend the equation FFB-DW = 0.61 RI + 0.25 body weight + 1.31, with a SEE of 2.1 kg and adjusted R2 of 0.95. This study demonstrated that RI with body weight can predict FFB with good accuracy in Whites 10-19 yr old.

Adipose Tissue↗
PubMed1992

Body fatness and risk for elevated blood pressure, total cholesterol, and serum lipoprotein ratios in children and adolescents.

BACKGROUND: Recent studies have shown considerable variation in body fatness among children and adolescents defined as obese by a percentile rank for skinfold thickness. METHODS: We examined the relationship between percent body fat and risk for elevated blood pressure, serum total cholesterol, and serum lipoprotein ratios in a biracial sample of 3320 children and adolescents aged 5 to 18 years. Equations developed specifically for children using the sum of subscapular (S) and triceps (T) skinfolds were used to estimate percent fat. The S/T ratio provided an index of trunkal fat patterning. RESULTS: Significant overrepresentation (greater than 20%) of the uppermost quintile (UQ) for cardiovascular disease (CVD) risk factors was evident at or above 25% fat in males (32.2% to 37.3% in UQ) and at or above 30% fat in females (26.6% to 45.4% in UQ), even after adjusting for age, race, fasting status, and trunkal fat patterning. CONCLUSIONS: These data support the concept of body fatness standards in White and Black children and adolescents as significant predictors of CVD risk factors. Potential applications of these obesity standards include epidemiologic surveys, pediatric health screenings, and youth fitness tests.

Adolescent↗
PubMed1992

The relative contribution of strength and physique to running and jumping performance of boys 7-11.

The purpose of this study was to determine the association of static strength with motor performance of 7 through 11 year old boys (N = 60) after accounting for differences in physique, i.e., body size, shape, and composition. Static strength measures included thigh extension, leg extension and plantar flexion measured by electronic transducer and back lift, leg lift, and right and left grips measured by spring dynamometer. Measures of body composition consisted of fat estimated from triceps, subscapsular and calf skinfolds, and fat-free body weight estimated from potassium-40 measurements. Body structure consisted of skeletal widths, and segment girths, lengths and volumes. The dependent variables were vertical jump, standing broad jump, 50-yard dash, 600-yard run and mile run. The measures of strength increased the variance accounted for from 10 to 23% over that when body size, composition and structure were used without strength. An exception was vertical jump where no increase in the variance accounted for was found with the addition of strength variables. The regression equations determined for the sample of 60 boys rendered multiple R's ranging from 0.64 (mile run) to 0.75 (50-yard dash). It was concluded that strength has a significant relation to motor performance and that its contribution can be better assessed after accounting for differences in body size, shape, and composition.

Anthropometry↗
PubMed1992

Exercise training and body composition in childhood.

The influence of exercise training on body composition changes in children is examined in terms of muscle, bone, and fat development. Because of the inexact body composition methodologies in general use and an over-reliance on the two-components system--fat and fat-free body--the extent of changes especially for muscle and bone with exercise training has not been well quantified. With the recent development of new methodologies these limitations may be overcome. The relationship of body composition to health related fitness is also explored with an emphasis on establishing fitness standards for body fatness and the need for research on the etiology of lower back pain and osteoporosis.

Body Composition↗
PubMed1991

Midwest wrestling study: prediction of minimal weight for high school wrestlers.

This study determined the validity of previously published or newly derived equations to predict fat-free body mass (FFB) in high school wrestlers from the midwestern United States. Five laboratories participated in the data-pooling study (total sample of 860 subjects). Measures included body composition by underwater weighing and anthropometric measurements of body mass, stature, and selected circumferences, diameters, and skinfolds. Cross-validation of selected equations to predict FFB revealed the lowest levels of error from the equations of Lohman, Thorland et al., Katch and McArdle, and Behnke and Wilmore. Modification of the constants in these equations or generation of new equations did not substantially reduce prediction error. Overall, total error for these top equations ranged from 2.44 to 2.59 kg. However, based on observed trends, this error was of lower magnitude with the younger and lighter subjects and of higher magnitude with the older and heavier subjects. We conclude that these equations could be used singularly or collectively to determine FFB, and a minimal weight could then be derived and assigned to a scholastic wrestler.

Adolescent↗
PubMed1991

The maximally accumulated oxygen deficit as an indicator of anaerobic capacity.

Recently, a procedure has been established for the determination of the maximally accumulated oxygen deficit (MAOD) (Medbo et al., J. Appl. Physiol. 64:50-60, 1988) as an indicator of anaerobic capacity. We hypothesized that, if MAOD were a valid indicator of anaerobic capacity, it should distinguish between aerobically and anaerobically trained athletes and correlate with other existing anaerobic testing measures. Subjects were four distance and five middle distance runners, three sprinters, and four controls. The subjects ran for 2-3 min at 125-140% of VO2max until exhaustion, and the accumulated O2 deficit for that run was calculated by an extrapolation procedure. Subjects also performed the Wingate cycle ergometer test and runs of 300, 400, and 600 m. (Only athletes performed the runs.) Post-exercise blood lactates were obtained following the supramaximal treadmill run. MAOD (in O2 equivalents-ml.kg-1) was higher for the sprinters (78) and middle distance runners (74) than for the long distance runners (56) and control subjects (56) (P less than or equal to 0.05), indicating a greater anaerobic capacity for the former two groups. Consequently, the relative anaerobic contribution was larger for the sprinters (39%) and middle distance runners (37%) than for the long distance runners (30%; P less than or equal to 0.05). Significant correlations were found between MAOD and both Wingate power and treadmill work for all subjects and between Wingate power, Wingate capacity, treadmill work, and 300 m time for the athletes, suggesting that relationships do exist among MAOD and other anaerobic test measures. Potential use of MAOD as an indicator of anaerobic capacity is therefore promising and should be further explored.

Adult↗