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Biomedical subjects

T G Feest

Publications and source records attributed to T G Feest.

At least 37 records · Page 2Linked to original sources
PubMed1990

Incidence of advanced chronic renal failure and the need for end stage renal replacement treatment.

OBJECTIVE: To determine the age related incidence of advanced chronic renal failure in two areas of England. DESIGN: Prospective study of patients newly identified as having advanced chronic renal failure within a two year period; subsequent monitoring of patients' clinical course for a further 26 months. SETTING: Devon and Blackburn. SUBJECTS: Those patients in a population of 708,997 who developed advanced chronic renal failure (serum creatinine concentration greater than 500 mumol/l) for the first time during a two year period. MAIN OUTCOME MEASURES AND RESULTS: 210 Patients (148 per million population per year) developed advanced chronic renal failure, 117 (51%) of whom were over 70. The age related incidence rose from 58 per million per year in those aged 20-49 to 588 per million per year in those aged 80 or over. Only 54% (113) of patients were referred to a nephrologist; 120 patients (57%) needed dialysis or died within three months of presenting without receiving dialysis, and 187 (89%) died or needed dialysis within three years. After those unsuitable for further treatment had been excluded, 78 patients per million population per year aged under 80 needed to start long term renal replacement treatment. CONCLUSIONS: Many patients suitable for renal replacement treatment are still not referred for nephrological opinion and are denied treatment. If the treatment rate in the United Kingdom rose from the 1988 rate of 55.1 per million per year to 78 per million per year then the number of patients receiving treatment would rise to about 800 per million. This is double the present number and has considerable but predictable resource implications for the NHS.

Adolescent↗
PubMed1990

Protocol for increasing organ donation after cerebrovascular deaths in a district general hospital.

In a district general hospital serving 303,000 people, deaths from cerebrovascular incidents over 12 months were analysed retrospectively. 8 patients who died in general wards were identified as potential organ donors. A working party then devised a protocol for managing such donors by transfer to the intensive care unit for support until organ retrieval could be arranged. In the first 19 months with the protocol, organs (1 heart, 2 sets of heart valves, 2 livers, and 16 kidneys) were retrieved from 8 patients who would not otherwise have become donors. If these results were replicated nationally a further 16.7 donors per million per year would be added to the current annual UK rate of 14.6 donors per million.

Adult↗
PubMed1983

Idiopathic hypercalcaemia of chronic dialysis.

Three women on different forms of maintenance dialysis developed persistent steroid-responsive idiopathic hypercalcaemia, with low calcium absorption, severe skeletal decalcification, multiple fractures, and severe clinical problems. Bone histology showed osteomalacia with suppression of osteoblast activity and no hyperparathyroidism. The disease persists at least six months after transplantation. The features are compatible with poisoning by a toxin with many similar properties to aluminium: we only found significant aluminium overload in one of these cases.

Adult↗
PubMed1983

Vibration sensory threshold: a guide to adequacy of dialysis?

The vibration sensory threshold (VST) is an easy non-invasive reproducible and sensitive bedside test of peripheral nerve function. It is impaired in pre-dialysis uraemic patients with no clinical evidence of peripheral neuropathy; tends to deteriorate during the first year of dialysis after which it remains relatively constant, and returns towards normal within one week of kidney allograft function. It is unrelated to type of dialysis, acetylator status, average serum creatinine values or serum aluminium. VST may be a valuable monitor of the adequacy of dialysis.

Female↗