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Biomedical subjects

T Fukuya

Publications and source records attributed to T Fukuya.

At least 37 records · Page 2Linked to original sources
PubMed1989

Single tuberculous stricture in the jejunum: report of 2 cases.

Intestinal tuberculosis is now considered rare. It usually involves the ileocecal region and often produces multiple ulcers in the small intestine. This is a report of 2 patients who presented with a single tuberculous stricture in the jejunum, an exceedingly rare manifestation of this disease. The stricture in each case consisted of a short girdle ulcer with irregular margins, detected by double-contrast studies of the small intestine.

Constriction, Pathologic↗
PubMed1984

[Case of yolk sac tumor decreasing in size and the normalizing of alph-fetoprotein level by anticancer chemotherapy].

A 19-year old man was hospitalized suspected of a mediastinal tumor with superior vena caval syndrome. As the chest X-ray film and thoracic CT scan on admission revealed a huge anterior mediastinal tumor, and the value of serum alpha-fetoprotein (AFP) was high, we made a diagnosis of malignant mediastinal tumor from the germ cell. Radiation therapy was not effective, but a combination chemotherapy consisted of cis-platinum, adriamycin, and vincristine was clearly effective, decreasing the size of the tumor and normalizing the value of serum AFP. As the tumor acquired tolerance to the anticancer drugs before long, the chemotherapy became ineffective and the patient died 9 months after the initiation of the treatment. This tumor had endodermal sinus structure, Schiller-Duval body, and eosinophilic hyaline globulus which were histological characteristics of yolk sac tumor, and was confirmed to be originated from anterior mediastinum.

Adult↗
PubMedDate not supplied

MR signal intensity changes in hepatic parenchyma with ductal dilation caused by intrahepatic cholangiocarcinoma.

MR images of the liver in 13 patients with surgically proven intrahepatic cholangiocarcinoma were reviewed retrospectively and correlated to the histologic analysis of surgical specimens. We paid special attention to the peripheral liver tissue with ductal dilation but without tumorous involvement. High signal intensity was observed in the hepatic parenchyma with ductal dilation on T1-weighted spin-echo images (8 of 12) and spoiled gradient-recalled echo images (seven of seven), as compared with the contralateral hepatic lobe without duct dilation. The high signal intensity was not suppressed with fat saturation and showed enhancement after administration of contrast (11 of 12). Concurrent portal venous obstruction did not have significant effect on these findings (P < .05). Correlation with pathologic specimens suggested that this enhancement was associated with periportal fibrosis. The etiology of the high signal intensity on unenhanced spin echo or gradient-recalled T1-weighted image remains unclear. Radiologists should recognize these findings and should distinguish these from tumor involvement or the arterial buffer response caused by portal venous obstruction.

Bile Duct Neoplasms↗
PubMedDate not supplied

Hepatocellular carcinoma with sarcomatous change: characteristic findings of two-phased incremental CT.

BACKGROUND: Because of its poor prognosis, the diagnosis of hepatocellular carcinoma with sarcomatous change (HCCSC) is clinically important. The purpose of this study is to elucidate the characteristic CT findings of HCCSC. METHODS: Two-phased dynamic incremental CT images of six histologically proven HCCSC were retrospectively reviewed. RESULTS: All tumors (100%) exhibited peripheral enhancement on delayed CT images. Lymphadenopathy was observed in 100% (six of six patients); intrahepatic metastases, in 83% (five of six). Both metastatic lesions showed findings similar to those of the primary hepatic tumors, such as peripheral enhancement. Histopathological delayed and/or prolonged peripherally enhanced areas consisted of viable cancer cells with sarcomatous changes. CONCLUSIONS: The appearance of HCCSC on CT is that of an irregularly demarcated intrahepatic mass with delayed or prolonged peripheral enhancement, frequently with intrahepatic metastases and lymphadenopathy.

Aged↗
PubMedDate not supplied

Radiologically identifiable intratumoral portal vein in intrahepatic cholangiomas: a diagnostic pitfall.

BACKGROUND: Although intratumoral patent portal vein (ITPV) is one of the characteristic features of benign hepatic lesions, ITPVs can be demonstrated in malignant tumors. We present the spectrum of MR and CT findings of ITPV identified in intrahepatic cholangiomas with pathological correlations. METHODS: The ultrasound, CT and/or MRI findings of pathologically-confirmed intrahepatic cholangiomas were reviewed and correlated with surgical specimen or autopsy findings. RESULTS: Intratumoral patent vessels were radiographically-demonstrated in 5 patients with intrahepatic cholangiomas. All intratumoral vessels were secondary or tertiary order portal vein branches. Some wall thickening was identified on pathological examinations. CONCLUSION: The radiological demonstration of intratumoral portal vein is not a specific sign of benignity. In the case of a hepatic tumor with a patent portal tract, cholangioma should be considered, as well as benign tumors or lymphoma.

Adenoma, Bile Duct↗
PubMedDate not supplied

Primary malignant lymphoma in the porta hepatis: a case report.

A case of primary lymphoma in the porta hepatis is presented here. Cholangiography, angiography, ultrasonography and computed tomography suggested the presence of a mass in the porta hepatis, but all these failed to demonstrate the tumor clearly. Magnetic resonance imaging was very useful in defining the characteristics of the tumor and in delineating its extent, though it was not specifically diagnostic.

Aged↗
PubMedDate not supplied

MR imaging of hepatocellular carcinomas: effect of Cu and Fe contents on signal intensity.

BACKGROUND: To elucidate the metallic factors contributing to the signal intensities of hepatocellular carcinoma (HCC) on T1-weighted magnetic resonance (MR) images and to determine whether or not changes in signal intensity contribute to the diagnosis of histological grading of HCC. METHODS: In 35 patients immediately after surgery, the quantities of water, lipid, copper (Cu), iron (Fe), and manganese (Mn) were determined in HCCs and the surrounding hepatic parenchyma. The correlations among these findings, the histopathological findings, and the signal intensities of T1-weighted MR images were evaluated. RESULTS: Among the 35 HCCs, 12 (34%) were of high intensity, 14 (40%) were isointense, and 9 (26%) were of low intensity on T1-weighted images versus the surrounding hepatic parenchyma. The paramagnetic ions, which contributed to the signal intensity patterns, were assumed to be Cu in HCCs (30.5 +/- 52.9 microg/g ww), and Fe in the livers (106.2 +/- 86.8 microg/g ww) and HCCs (87.7 +/- 49.1 microg/g ww). In 12 HCCs with high intensity, one was grade I, eight were grade II, and three were grade III according to Edmondson-Steiner's histopathological classification. CONCLUSIONS: Signal intensity and signal intensity patterns alone cannot be signs of low-grade malignancy because of the Fe in livers and in HCCs.

Aged↗
PubMedDate not supplied

Helical CT evaluation of arterial invasion in pancreatic tumors: comparison with angiography.

BACKGROUND: Although helical computed tomography (HCT) has been widely employed for the evaluation of pancreatic tumors, its capability in the diagnosis of peripancreatic arterial invasion has not been established. METHODS: HCT with a sequential cine-display was carried out in 34 patients with solid pancreatic tumors and 28 control subjects without angiographic abnormality. The HCT scans were compared with angiograms. RESULTS: All major arteries (celiac, superior mesenteric, splenic, gastroduodenal) and superoanterior pancreaticoduodenal arteries were well demonstrated by HCT in control subjects. However, posterior pancreaticoduodenal arcades and other smaller arteries were poorly identified. Although 19 major arterial invasions were equally diagnosed by HCT and angiography in patients with pancreatic tumors, only 4 of 11 minor arterial invasions were correctly diagnosed by HCT. CONCLUSIONS: Although HCT has some limitations in the evaluation of minor peripancreatic arteries, it can provide enough information for making a decision about conducting pancreatic surgery.

Aged↗
PubMedDate not supplied

Chronic expanding hematoma of the spleen caused by angiomyolipoma in a patient with tuberous sclerosis.

We report a case of a chronic expanding hematoma caused by an angiomyolipoma of the spleen in a patient diagnosed with tuberous sclerosis in infancy. Computed tomography showed large bilateral renal angiomyolipomas. A splenic mass that increased in size during the follow-up period of 62 months was also noted. A large subcapsular hematoma of the spleen finally developed, and a splenectomy was performed. The splenic mass consisted of a chronic hematoma with prominent granulation tissue, which was considered to be caused by repeated bleeding from a small angiomyolipoma in the spleen.

Adult↗
PubMedDate not supplied

Treatment of hepatic encephalopathy by retrograde transcaval coil embolization of an ileal vein-to-right gonadal vein portosystemic shunt.

A 43-year-old non-cirrhotic woman suffered from encephalopathy caused by an extrahepatic portosystemic shunt between the ileal vein and inferior vena cava via the right gonadal vein. Percutaneous transcatheter embolization with stainless steel coils was performed by the retrograde systemic venous approach. Encephalopathy improved dramatically.

Adult↗
PubMedDate not supplied

Temporary spontaneous regression of intrahepatic cholangiocarcinoma.

A 34-yr-old man with a liver mass was referred to the hospital. The mass showed temporary spontaneous regression during the follow-up, however, subsequent regrowth of the tumor prompted surgical resection. The specimen revealed intrahepatic cholangiocarcinoma with two distinct components which had been clearly demonstrated on serial CT. Spontaneous resolution of a lesion does not necessarily suggest the lesion's benign, self-limiting entity. Intrahepatic cholangiocarcinoma should be included in the tumors that could spontaneously regress.

Adult↗
PubMedDate not supplied

CT findings of plexiform neurofibromatosis involving the ileum and its mesentery.

We present a case of plexiform neurofibromatosis involving the ileum and its mesentery. Computed tomography (CT) scans showed a cluster of small soft-tissue density nodules, which represented a cross-sectional image of the enlarged peripheral nerves and wall thickening of the distal ileum. Trapped fat tissue was demonstrated between these enlarged nerves. Histopathologic studies of the resected specimen correlated well with CT findings.

Adult↗
PubMedDate not supplied

CT of abdominal abscess with fistulous communication to the gastrointestinal tract.

We review CT of 24 cases of intraabdominal abscess with fistulous communication to the GI tract confirmed by GI contrast study or fistulogram. Underlying causes of fistulization included recent GI tract surgery (13), diverticulitis (four), unknown etiology (three), malignant neoplasm (two), trauma (one), and pancreatitis (one). Thirteen (54%) abscesses showed air-fluid levels, 14 (58%) showed air bubbles, and seven (29%) showed both. Bowel contrast material was administered in 21 cases, and optimal bowel opacification was effected in 16. However, contrast extravasation into the abscess was noted in only six cases. We conclude that an air-fluid level may indicate the presence of a fistulous communication to the GI tract, but its absence does not necessarily mean there is no communication. Also, recognition of contrast within the abscess is uncommon even with optimal bowel opacification. In cases of clinical suspicion of internal fistula, a fistulogram or GI contrast study should be performed.

Abdomen↗
PubMedDate not supplied

MRI of primary lymphoma of the liver.

OBJECTIVE: The MR findings in two cases of primary lymphoma of the liver (PLL) are presented. MATERIALS AND METHODS: MR of two cases of primary lymphoma of the liver were reviewed and its features were estimated. RESULTS: Both cases showed a solitary large liver mass. On T1-weighted imaging the tumor was isointense in one and homogeneously hypointense to the liver parenchyma in the other. On T2-weighted imaging both tumors were homogeneously hyperintense. In one case the margin of the tumor was poorly defined, and portal branches were identified within the tumor, an unusual finding in other liver neoplasms. CONCLUSION: In patients with liver masses with homogeneous intensity on MR but without liver dysfunction and other malignancies, PLL should be included in the differential diagnosis.

Aged↗