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Biomedical subjects

T Fukumitsu

Publications and source records attributed to T Fukumitsu.

At least 37 records · Page 2Linked to original sources
PubMed1984

[Facial nerve schwannomas: report of two cases].

Although schwannoma may arise from any true cranial nerve, it is well known that the acoustic and trigeminal nerves are frequent origins. Schwannomas of the facial nerve are rare. In this communication, two cases of facial nerve schwannoma arose from the horizontal portion are reported. Case 1. A 44 year-old male was admitted to our clinic complaining of left hearing loss and facial asymmetry. About three years prior to the admission, he first noticed left hearing disturbance which was gradually deteriorated and was transiently accompanied by left tinnitus during the progression. Then muscle spasm developed on the left eyelid which resolved spontaneously in a few weeks, then asymmetry of the face developed. Neurological examination on admission revealed left hearing loss and left peripheral facial palsy. As a result of neuro-otological examinations, left hearing impairment and left facial palsy were thought to be due to retrocochlear and suprageniculate lesions respectively. Plain skull radiograms and tomograms revealed marked destruction of left pyramis and enlarged internal auditory canal. Computed tomography of the brain showed low-density mass in the left middle fossa and defect of the tip of the left pyramis. After bolus injection of contrast material, peripheral portion of the middle fossa mass was enhanced non-homogeneously and enhanced mass extended to the posterior fossa. Left middle and posterior fossas were explored by carrying out a osteoplastic temporal flap and suboccipital craniectomy. A large extradural mass was noted to have filled the middle fossa which extended to the posterior fossa through destroyed pyramis and enlarged internal auditory canal. The tumor was removed subtotally.(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗
PubMed1984

[Facial palsy following head injury: topognosis, prognosis and indications for surgical decompression].

It is a common experience that the facial nerve is affected in closed head injury. 781 patients with head injury were treated at Kobe Central Municipal Hospital over a period of 5 years from January 1977 to April 1982, and facial palsy occurred in 25 cases (3.2%). The male to female ratio was 22: 3 and age ranged from 9 to 78 (average 36). The patients were studied, using radiological, topognostic and electrodiagnostic methods. Facial nerve decompression was done in 5 cases and 20 cases were treated conservatively. Results were as follows. The overall rate of complete recovery was 64% (16 of 25 cases). In the conservative treatment group, all patients with incomplete paralysis and normal maximal stimulation test (MST) recovered completely. With complete paralysis, if the initial nerve excitability (MST) was normal, recovery could be expected by conservative treatment. Even if the patients had abnormal nerve excitability (MST) at first, complete recovery could be observed, when signs of recovery could be elicited and normalization of MST occurred within 3 weeks from the onset of the palsy. In severe cases, even with abnormal MST from the onset, complete or partial recovery can be expected after surgery. Therefore, microsurgical decompression of the facial nerve is indicated in the following cases: patients with complete paralysis and no response to MST from the onset. patients with complete paralysis and deteriorating response to MST 1 month after onset. Maximal stimulation test is a good guide for determining the necessity for surgical intervention.

Accidents, Traffic↗
PubMed1982

[Giant cell tumor of the temporal bone--case report (author's transl)].

The majority of giant cell tumors occurs in the long bones, especially around the knee, and only 1.4-1.8% of cases are found in the skull. In this communication, a case of giant cell tumor of the temporal bone is reported because of a rarity of the lesion in the skull. The 37-year-old housewife was admitted to our clinic complaining of swelling in right temporal region which had gradually developed over a two-month period. On examination, there was a swelling about 5cm in diameter beneath right temporal muscle; its surface was smooth and its consistency was hard. Tenderness was found in its center. Routine x-ray of the skull showed osteolytic lesion in right temporal bone with relatively clear margins. Computed tomography demonstrated heterogeneously high-density mass in right temporal bone and right middle fossa. The tumor located mainly within the temporal bone at the middle fossa, and intracranial epidural space at the convexity. After bolus injection of contrast material, the tumor of temporal bone and the peripheral portion of the intracranial tumor were enhanced markedly. Right external carotid angiograms disclosed tumor stain in capillary and venous phases. Abnormal RI uptake was disclosed by bone scintigrams with 99mTC-methylene diphosphonic acid. Her preoperative diagnosis was calvarial tumor with intracranial extension. A right fronto-temporal osteoplastic craniotomy was performed. The tumor located within the temporal bone and in epidural space which invaded temporal muscle and underlying dura. The tumor was elastic soft and vascular with central necrosis. The tumor was extirpated totally including surrounding temporal muscle and dura. Microscopic examination of the operative specimen revealed giant cell tumor of the skull. Therefore, she was treated with 60CO irradiation (3,000 rads) to the temporal region. In the 13 months since the completion of treatment, there has been no sign of recurrence nor metastasis. Giant cell tumor of the skull were reviewed with special references to diagnosis and treatment. Computed tomographic findings of this tumor were also discussed briefly.

Adult↗
PubMed1981

Prepontine epithelium-lined cyst. Case report.

A 30-year-old woman presented with recurrent episodes of severe headache associated with visual disturbances. Neurological examination showed minimal neurological defects. Angiography, computerized tomography, and radioisotope cisternography revealed a large cyst in the prepontine region, which did not communicate with either the subarachnoid space or the ventricular system. Histologically, the cyst was lined by columnar and/or cuboidal cells, which contained materials positive on periodic acid-Schiff staining. Ultrastructurally, there were two types of cells, ciliated and noncillated. Characteristic findings were continuous basement membrane, microvilli covered with electron-dense material, several intercellular junctional devices, and an open intercellular space which was occasionally filled with a migrating cell. These findings would support the view that the epithelial cyst with such features was derived from endodermal tissues rather than from neuroepithelium. Electron microscopic examination is indispensable in making a correct diagnosis of intracranial cysts.

Adult↗
PubMed1977

[RI cisternography in the diagnosis of brain tumors (author's transl)].

Fifteen cases of brain tumors of supratentorial location were studied by RI cisternography; Cisternographical patterns of decreased or absent radioactivity were classified into five groups as follows: Pattern I: Sharply circumscribed and localized decrease in radioactivity; Pattern II:Ill-defined and focal decrease in radioactivity; Pattern III: Areal decrease in radioactivity involving one whole or two lobes; Pattern IV: Hemispherical decrease in radioactivity and Pattern V: Total decrease in radioactivity in the head. Each pattern appears to correspond well with topographical features of brain tumors and their related pathology, such as extracerebral tumors (pattern I), intracerebral but superficially located tumors (pattern II), extracerebral tumors with surrounding edema or large intracerebral tumors (pattern III), extracerebral or intracerebral tumors with increased intracranial pressure (pattern IV), and extremely increased intracranial pressure regardless the site of tumor (pattern V). In consideration of these patterns, RI cisternography would be a more useful supplementary method in diagnosis of brain tumors to detect the area involved, to differentiate an intracerebral from an extracerebral tumor, and to find a recurrence of the tumormfurthermore, it is helpful to know the therapeutical effects of surgery and radiotherapy. RI cisternography is a simple, relatively noninvasive method which can be used more widely.

Adolescent↗
PubMed1976

Mycotic aneurysms of the internal carotid artery. Case report.

The authors report a case with two mycotic aneurysms in the cavernous portion of the internal carotid artery, presumably secondary to a transient bacteremia from pneumonia. The strikingly rapid development of the aneurysms was demonstrated by angiography. Painful total ophthalmoplegia and extophthalmos were the main clinical features.

Adult↗
PubMed1976

[RI cisternography with 111-In-DTPA].

In contrast to 169Yb-DTPA the usage of 111In-DTPA, a new radiopharmaceutical, is not as yet popular for RI cisternography. This report deals with a comparative study of these two radiopharmaceuticals for RI cisternography. For the past one year 301 RI cisternography. For the past one year 301 RI cisternographies were performed in 160 cases at the Neurosurgical Survice of Shizuoka Rosai Hospital. Among those 169Yb-DTPA was used in 137 occasions, 111In-DTPA in 53, and both 169Yb-DTPA and 111In-DTPA in 30. The results of this study were as follow. 1. 111In-DTPA was chemically stable in intrathecal administration. 2. A reactive fever was minimal with 111In-DTPA if any. 3. There was no adverse reaction, such as aseptic meningitis, following 111In-DTPA cisternographies. 4. The effective half-life of 111In-DTPA was 16 hours, and that of 169Yb-DTPA 22 hours in this series. This means the men were exposed to radioactivity less with 111In-DTPA than with 169Yb-DTPA. 5. However, there was no difference in diagnostic value between these two radiopharmaceuticals, even 48 hours after intrathecal administration. From this study 111In-DTPA appears to be more suitable for RI cisternography than 169Yb-DTPA.

Adult↗
PubMed1976

Migration of plasticiser from haemodialysis blood tubing.

Di-2-ethylhexyl phthalate (DEHP) was found to migrate from polyvinyl chloride (PVC) blood tubing into human blood during both in vivo and in vitro haemodialysis. DEHP blood level increased during in vivo dialysis but decreased again toward the end of a six hour dialysis period. During in vitro haemodialysis of outdated human blood DEHP accumulated up to 5580 ppb. Although toxic effects have not yet been observed, we believe plastic tubing that does not contain extractable materials should be developed.

Diethylhexyl Phthalate↗