[History of bacteriology in Japan (14)].
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Biomedical subjects
Publications and source records attributed to T Fujino.
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TThe effect of prostaglandin F 2 alpha was studied clinically and electromyographically on the motility of the gastric antrum, duodenum, jejunum, ileum and transverse colon in 20 patients by giving 2 hours intravenous drip infusion at 0.3 approximately 0.5 microgram/kg/min for 2 hours after major abdominal surgery. Folling results were obtained. 1. The motility of stomach and colon was least active than any other site of alimentary tract during 48 hours after surgery. This seems to be one of the most important causes of so called postoperative ileus. 2. Recovery from reflex inhibition of motility of the alimentary tract after surgery was seen in duodenum at first, and then in jejunum and ileum in order. It was proved that intravenous drip infusion of PGF 2 alpha at 0.3 approximately 0.5 microgram/kg/min for 2 hours had produced the increase of electrical activity in any site of gastrointestinal tract and subsequently brought about increasing of propulsive movement. The effect of PGF 2 alpha is proportional to its concentration. 4. tit was concluded that PGF 2 alpha could be administered most effectively by intravvenous drip infusion at 0.5 microgram/kg/min 3 times daily for 3 days after surgery for the satisfactory recovery from the postoperative ileus, and no appreciable side effect was observed.
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We present two new, one-stage methods for resurfacing a part of the face-- (1) the microvascular transfer of a free retroauricular flap, and (2) an island flap from the galea covered by a full-thickness skin graft from the retroauricular region. Both procedures provided the same good color match, without leaving a readily visible donor scar.
We present a successful clinical case (perhaps the first) of primary reconstruction of the breast after radical mastectomy by use of a free skin-fat-muscle flap.
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Examination with the S.E.M. shows that 5 days after surgery the microanastomoses area is covered with pseudointima, and the regeneration of the intima is completed within two weeks. Comparing the two different suture techniques (large bites and small bites), there are no differences between them in the resultant patency rates. The large bites produce less immediate leakages. There were no significant differences in the process of intimal healing.
A case of 42-year-old female with persistent pericardial effusion and recurrent congestive heart failure was presented. The clinical course, laboratory and cardiac evaluations confirmed the existence of tricuspid incompetence and restrictive condition of the right ventricle. At autopsy, the right atrium and ventricle showed moderate hypertrophy, the left ventricle being almost completely spared macroscopically. Diffuse fibrous thickening of the right atrial and ventricular endomyocardium with mural thrombi, and mild lymphocytic infiltation were noted microscopically. These findings are compatible with endomyocardial fibrosis described by Davies. The etiology and pathogenesis of the disease were discussed.
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