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Biomedical subjects

T Fritz

Publications and source records attributed to T Fritz.

At least 73 records · Page 4Linked to original sources
PubMed1991

Percutaneous transpenile and retrograde venous occlusion for the treatment of venous leak impotence.

In 17 patients percutaneous transpenile venous occlusion was performed for the treatment of so-called venous leak impotence. Because of primary failure, the procedure was repeated in 5 patients. On four occasions, it was combined with a retrograde venous occlusion via the internal iliac vein. Within a rather short follow-up period of 23 months maximum, the overall success rate is 65%. Six patients are able to have intercourse and 5 others need additional intracavernous injections. Complications of the procedure were not observed.

Adult↗
PubMed1990

The predictive role of bioelectrical impedance analysis (BIA) in postoperative complications of cancer patients.

The correlation between body composition measured by bioelectrical impedance (BIA) and postoperative complications in 115 patients with gastrointestinal cancer was analysed. A significant increase in severe complications was found independent of lean body mass (LBM). In patients with LBM below the normal range the complication rate proved to be 31% (17/55), whereas patients with normal LBM had a complication rate of 10% (6/60). Other decisive factors, such as sex, age, tumor stage, operative procedure and body height were equally distributed in both groups. The practicability and efficiency of BIA became obvious in this study.

Adult↗
PubMed1989

Tissues at the surface of the new composite material titanium/glass-ceramic for replacement of bone and teeth.

A new composite implant material titanium/glass-ceramic was tested in rabbits using light microscopy, histomorphometry, and biomechanical testing methods. Two rabbit implant models were used. The first premolar tooth was replaced and cylinders inserted into the trabecular bone of the distal femur below the patella sliding plane. There was bone bonding to the glass-ceramic component and additional mechanical interlocking, due to bone ingrowth between the titanium matrix into secondary pores. This was proved by measuring the tensile strength at the interface of the new composite material which was in the same range as compared to pure glass-ceramic implants. In tooth replacement there was a tight attachment of gingival epithelium and stroma to composite titanium/glass-ceramic. These results are of particular clinical interest: physicochemical bone bonding and additional mechanical interlocking result in a resistance of the implant material against shear and tensile loads at the interface. Therefore this new composite material should be suitable for further load-bearing applications.

Animals↗
PubMed1989

[Transpenile venous occlusion in the treatment of erectile impotence].

In 15 of 18 patients, 2 of them with previous surgery, transpenile venoablation was performed for treatment of erectile dysfunction due to cavernous leakage. In 4 this was combined with retrograde venooclusion via the internal iliac vein. In 4 patients normal erectile status could be obtained. In 3 other patients erections became possible with use of intracavernous vasoactive agents. In two only mild amelioration, and in two others no change of erectile dysfunction were obtained. Follow-up studies are yet missing in 3 patients. Complications of the procedure were not observed.

Adult↗
PubMed1988

[Anesthesia for eye operations in mitochondrial encephalomyelopathy].

Mitochondrial encephalomyopathy involves a disturbance of the mitochondrial respiratory chain, as a result of which the blood lactate level is elevated. In stress situations a lactate acidosis can occur. The disease may be subdivided into three main syndromes: Kearns-Sayre syndrome (KKS), "myoclonus epilepsy with ragged red fibers syndrome" (MERRF), and "mitochondrial myopathy, encephalopathy, lactic acidosis and strokelike episodes syndrome" (MELAS). There are also several intermediate forms. Ophthalmological symptoms are frequent and occasionally have to be treated surgically. A 20-year-old male patient with a mixed form of these syndromes including elements of KSS and MERRF had to undergo cataract extraction. The authors decided to perform the operation under local anesthesia and sedation, with the anesthetist on standby. No problems arose. In all cases where mitochondrial encephalomyopathy is suspected the diagnosis should be confirmed by a muscle biopsy and the risk of cardiac arrest, respiratory insufficiency, and epileptic seizures ruled out prior to surgery. Local anesthesia with sedation appears to be the most favorable form of anesthesia provided the maximum dose is observed and a substance with a high convulsion threshold is chosen. Perioperative monitoring by an anesthetist and temporary provision of a cardiac pacemaker are necessary.(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗
PubMed1988

[Comments on anesthesia procedures in mitochondrial encephalomyopathy].

Mitochondrial encephalomyopathies (MEMP) are rare diseases caused by a disturbance of the mitochondrial chain of respiration. This prevents pyruvate from being completely integrated into the tricarboxylic acid (Krebs') cycle, and hence there is an accumulation of lactate. Histologically this is marked by the appearance of "ragged red fibres" in the light microscope which, in the electron microscope, are eventually recognised as typical accumulations of pathological mitochondria. The clinical pattern can vary greatly and ranges from ophthalmoplegia via mainly myopathic to encephalopathic forms. The pattern of signs and symptoms enables subclassification into three main syndromes (10): The Kearns-Sayre syndrome (KSS), "myoclonus epilepsy with ragged red fibres syndrome" (MERRF) and "mitochondrial myopathy, encephalopathy, lactic acidosis and strokelike episodes syndrome" (MELAS). Intermediate types, however, are frequent. Furthermore, quite a large number of other syndromes such as the "Toni-Fanconi-Debré syndrome" can be classified among the group of mitochondrial encephalomyopathies.--The patient must be classified as a risk patient. Disturbances of cardiac conduction may require a transient or permanent pacemaker. Increase in oxygen requirement must be avoided to prevent increase in lactate levels and development of lactate acidosis. The severity of the myopathy makes it necessary to exercise caution in the use of benzodiazepines and long-term relaxants. When using local anaesthetics one should consider both their negative dromotropism and the resulting reduction of the epileptic threshold. There is a relative contraindication for spinal and epidural anaesthesia.(ABSTRACT TRUNCATED AT 250 WORDS)

Anesthesia, General↗
PubMed1988

[Complaints in the postoperative phase related to anesthetics].

In two prospective, randomized studies the frequency of headache, nausea, vomiting, and analgesic requirement during the first postoperative 24 h was observed in order to study differences between the sexes and the inhalation anesthetics halothane, enflurane, isoflurane, or balanced anesthesia with enflurane/alfentanil. Nausea and vomiting were more frequent after enflurane than after halothane or isoflurane. There was no significant difference between anesthetics and frequency of headache, but there were significant differences in postoperative analgesic requirements which were highest after halothane and lowest after isoflurane. Postoperative complaints were always significantly greater among women than among men. The second study indicated that balanced anesthesia did not reduce the analgesic requirement compared to enflurane without alfentanil, but lead to a higher incidence of vomiting. After premedication with flunitrazepam and atropine and combined with 70% N2O/30% O2, isoflurane was the most favorable anesthetic agent with regard to the parameters studied. Balanced anesthesia with enflurane/alfentanil did not show any advantages for patients in the postoperative phase under the given conditions.

Adolescent↗
PubMed1987

[Value of systemic streptokinase therapy in thromboembolism diseases].

Among 27,756 cases with stationary treatment 1,532 patients were found in whom a systemic fibrinolysis therapy was taken into consideration. Under strict attention to indications and contraindications 173 patients were treated with streptokinase. The rate of treatment failures in peripheral arterial obstructions was 46%, in venous thromboses 29%. The lethality of pulmonary embolisms could be decreased significantly, in acute myocardial infarction however, it could not be reduced. In 10% of the cases we observed severe therapeutic complications. The systemic streptokinase therapy is therefore a certainly effective, but also high-risk method of treatment, which must be performed by an experienced physician.

Humans↗
PubMed1987

[Bronchoplastic and angioplastic operations in bronchial carcinoma].

The various forms of bronchoplastic and angioplastic procedures are the best means of avoiding pneumonectomy. Essential indications are limited respiratory reserve and central site of a malignancy. In a retrospective study 248 broncho- and angioplastic operations carried out in the years 1973 to 1983 were analyzed. Reference date for the analysis of survival was January 1986. In consequence the minimum period of follow-up was two years. For all patients (n = 248) the 5-year-survival was 22% with a 30-day-lethality of 13%. The 5-year-survival of all bronchial sleeve resections operated radically (stage I and II of the TNM-classification) (n = 44) was 42% with a 30-day-lethality of 7%. The 5-year-survival of all bronchoplastic operations of stage I and II (n = 88) was 38% with a 30-day-lethality of 14%. Improved suture material and surgical techniques caused a reduction of operative lethality from 23% to 8% during the described period. In the first thirty postoperative days the following complications caused death: Hemoptysis (n = 5), insufficiency of the anastomosis (n = 3), right heart failure (n = 5), pulmonary embolism (n = 4) and sepsis (n = 1).

Anastomosis, Surgical↗
PubMed1983

Venous obstruction. A potential complication of transvenous pacemaker electrodes.

Pervenous endocardial pacing using a self-contained, totally implantable system was popularized in this country by Chardack in 1965 and subsequently has become the established mode of permanent pacing. Although this intervention may be lifesaving, it is not without risk. Occlusion of major vessels incited by the presence of a pacing electrode is an extremely rare occurrence. We describe four patients who had occlusion of the axillary or subclavian veins or of the superior vena cava due to pervenous pacing electrodes. We review the literature of previous observation of venous occlusion and thromboembolic complications due to pervenous pacemakers, describe the clinical features accompanying venous obstruction, and review pathophysiology and proposals for treatment. The use of noninvasive radionuclide venography serves as a useful adjunct in the diagnosis of venous obstruction from pacing catheters.

Aged↗