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Biomedical subjects

T Franquet

Publications and source records attributed to T Franquet.

At least 37 records · Page 2Linked to original sources

The crazy-paving pattern in exogenous lipoid pneumonia: CT-pathologic correlation.

OBJECTIVE: The purpose of our study was to show a distinctive appearance of exogenous lipoid pneumonia on thin-section CT that has not, to our knowledge, been previously documented. CONCLUSION: On thin-section CT, exogenous lipoid pneumonia is revealed as patchy well-defined areas of ground-glass attenuation with superimposed septal thickening (crazy-paving pattern). Exogenous lipoid pneumonia should be included in the differential diagnosis when thin-section CT reveals a crazy-paving pattern.

Aged↗

Imaging findings of sternal abnormalities.

Radiographic findings in the sternal abnormalities are often nonspecific, showing appearances from a localized benign lesion to an aggressive lesion as seen with infections and malignant neoplasms. A specific diagnosis of sternal abnormalities can be suggested on the basis of CT and MR characteristics. Familiarity with the presentation and variable appearance of sternal abnormalities may aid the radiologist is suggesting a specific diagnosis. We present among others characteristic radiographic findings of hemangioma, chondrosarcoma, hydatid disease, and SAPHO syndrome. In those cases in which findings are not specific, cross-sectional imaging modalities may help the clinician in their management.

Adult↗

Nonpalpable, well-defined, probably benign breast nodule: management by fine-needle aspiration biopsy and long-interval follow-up mammography.

The management of nonpalpable, well-defined breast nodules by short-interval, 6-month follow-up mammography is widely accepted. We have, however, been managing these type of lesions with fine-needle aspiration biopsy (FNAB), guided by sonography or stereotaxic approach, in order to reduce the number of follow-up mammograms. We recommended surgical biopsy only in cases with malignant or suspicious cytology. Patients with benign cytology or inadequate sample were included in a 12-month-interval mammography surveillance program. In the series we present, two carcinomas were diagnosed among 145 lesions (1.38 %). Both had shown malignancy in FNAB. Another two cases, suspicious of malignancy in FNAB, finally resulted benign in histology. The remaining 141 nodules, monitored for at least 2 years, or surgically removed at the patient's request, have not shown signs of malignancy, regardless of a diagnosis of either benign or inadequate sample in FNAB. Sensitivity and negative predictive value of FNAB have therefore been 100 % in this series. No notable differences were observed between stereotaxic and sonographic guidance, except the percentage of inadequate samples (20.3 % by sonography; 25.9 % by stereotaxic sampling). We conclude that stereotaxic or sonographic FNAB is a very accurate diagnostic method in lesions of this type, allowing long-interval surveillance of the nodules with nonsuspicious cytological results.

Biopsy, Needle↗

Primary Sjögren's syndrome and associated lung disease: CT findings in 50 patients.

OBJECTIVE: We prospectively evaluated the high-resolution CT findings in 50 nonsmoking patients with proven primary Sjögren's syndrome. CONCLUSION: High-resolution CT is a sensitive technique in assessing pulmonary involvement in patients with primary Sjögren's syndrome. Interstitial lung disease and bronchiolar inflammatory changes are common abnormal findings seen on CT scans in primary Sjögren's syndrome.

Adult↗

[Bronchiolitis associated with ulcerative colitis].

Inflammatory bowel disease (IBD) only occasionally affects the lung. Noteworthy among the various pulmonary entities related to IBD are chronic bronchitis and bronchiectasis, though reports of bronchiolitis, obliterants bronchiolitis with organizing pneumonia and other interstitial diseases have also been published. Given the rarity of such pneumopathy, we report a case of bronchiolitis in a patient with a prior diagnosis of ulcerative colitis. We discuss the radiological findings and the results of lung function testing, emphasizin the utility of corticosteroid treatment, which usually leads to a good outcome in pneumopathy secondary to IBD.

Administration, Oral↗

Imaging of pulmonary-cutaneous disorders: matching the radiologic and dermatologic findings.

Dermatologic lesions are often associated with pulmonary disorders and vice versa. Diseases with pulmonary and cutaneous manifestations can be divided into four major categories: (a) congenital and developmental disorders with cutaneous-pulmonary manifestations (Ehlers-Danlos syndrome, generalized elastolysis, yellow nail syndrome, neurofibromatosis, hereditary hemorrhagic telangiectasia); (b) primary dermal diseases with associated pulmonary manifestations (septic vasculitis, malignant melanoma, Kaposi sarcoma); (c) primary pulmonary diseases with associated cutaneous manifestations (tuberculosis, Pseudomonas pneumonia, mycoplasmal pneumonia, adenocarcinoma, metastasis); and (d) cutaneous-pulmonary conditions (multisystem disorders) (progressive systemic sclerosis, systemic lupus erythematosus, Wegener granulomatosis, sarcoidosis). A series of selected cases is used to illustrate the radiologic and dermatologic features of conditions that affect both the lung and dermal tissue. Specific emphasis is placed on the dermatologic manifestations of disease. Diagnosis of a pulmonary-cutaneous disorder requires familiarity with the morphologic appearance of the cutaneous lesion.

Adult↗

Chylothorax due to Mycobacterium tuberculosis.

Chylothorax in an adult is a rare cause of pleural effusion. Mycobacterium tuberculosis may cause chylous effusion, but usually in association with extensive intrapulmonary involvement. A case of chylothorax is presented in which M tuberculosis was isolated from the pleural fluid and was the only intrathoracic manifestation of tuberculosis.

Aged↗

Malignant neuroectodermal tumour of the chest wall (Askin tumour): CT and MR findings in eight patients.

Malignant neuroectodermal tumour of the chest wall (Askin tumour) is an uncommon malignant neoplasm affecting young adults. We retrospectively reviewed the clinical and pathological information and radiologic studies in our archives on eight cases of this tumour. All cases were pathologically proven. Plain films, CT scans and radionuclide images were available in all cases. MR images were also available in two patients. Although rare, Askin tumour should be included in the differential diagnosis when a chest wall or thoracic paraspinal mass is identified in a young individual.

Adolescent↗

Spiculated lesions of the breast: mammographic-pathologic correlation.

Spiculated breast lesions may be caused by both benign and malignant processes, including sclerosing adenosis, postsurgical scar, radial scar, tuberculosis (rare), posttraumatic oil cysts, infiltrating ductal carcinoma, ductal carcinoma in situ (rare), infiltrating lobular carcinoma, and tubular carcinoma. Mammographically, such lesions are often similar, and only some can be differentiated on the basis of morphologic characteristics. Although microcalcifications are often associated with breast carcinoma, not all spiculated lesions with microcalcifications are malignant. Sclerosing adenosis occurs with punctate microcalcifications, but the lesion often has a radiolucent center, compared with the opaque center generally found in malignant spiculated lesions. Radial scar may occasionally occur with microcalcifications and usually has a radiolucent center, but the latter is not a reliable criterion for differentiation from carcinoma. The spicules of benign lesions are often caused by fibrous tissue, lipid-filled spaces surrounded by histiocytes, or sclerotic stroma, whereas the spicules of malignant lesions are due to tumor infiltration, desmoplastic response, or periductal fibrosis. Mammography alone is frequently not reliable for making the specific diagnosis. Clinical breast examination, additional mammographic views, and needle or surgical biopsy are often required.

Adult↗

Increased density of the azygos lobe on frontal chest radiographs simulating disease: CT findings in seven patients.

OBJECTIVE: Our objectives were to show that an opaque azygos lobe on the anteroposterior chest radiograph can be a normal finding and to investigate the causes of the increased density. MATERIALS AND METHODS: We prospectively examined 53 patients seen during a 3-year period in whom an azygos lobe was detected on chest radiographs. The size of the lobe was determined by the location of the trigone on chest radiographs. The trigone is the triangular area that marks the upper portion of the azygos fissure. If the trigone was located on the lateral aspect of the pulmonary apex, the azygos lobe was classified as type A (nine patients); if the trigone was situated at the midpoint of the cupula of the apex, the lobe was considered type B (20 patients); if the trigone was located on the medial face of the apex, the lobe was considered type C (24 patients). An opaque azygos lobe was defined as an increase of density suggestive of a pulmonary or mediastinal process. The findings on chest radiographs were compared with those on CT scans, which were obtained in all patients. RESULTS: Radiographs showed abnormally opaque azygos lobes in seven patients. Three cases were type B and the opaque lobe had a triangular aspect, suggesting pulmonary disease. Four cases were type C and the opacity had a convex aspect, suggesting a mediastinal mass. In all cases, CT scans showed a shallow azygos lobe and increased depth of the soft tissues of the mediastinum in front of the azygos lobe. This appearance was caused by tortuosity of the supraortic vessels in six cases and by a shadow from a normal thymus in one case. No pathologic process was discovered in any of the patients. CONCLUSION: We believe an opaque azygos lobe can be a normal finding, usually resulting from overlapping tortuous supraortic vessels.

Adolescent↗

Stereotaxic fine-needle aspiration of low-suspicion, nonpalpable breast nodules: valid alternative to follow-up mammography.

Seventy "low-suspicion," nonpalpable solid breast nodules were evaluated with stereotaxic fine-needle aspiration with cytologic analysis as an alternative to follow-up mammography. Sonography was performed in all cases to determine the solid nature of the nodules. Eight cysts were incorrectly classified with sonography, corresponding to atypical cysts; in such cases, however, stereotaxic fine-needle aspiration not only enabled the diagnosis, but was therapeutic as well. Fifty-eight of 70 breast aspirates (83%) yielded adequate cellular material for cytologic interpretation. A specific cytologic diagnosis was made in 52 cases (51 benign, one malignant). Insufficient cytologic material was obtained in 12 cases (17%). These results should help establish the validity of stereotaxic fine-needle aspiration with cytologic analysis as an alternative to follow-up mammography in patients with low-suspicion, solid breast nodules, reducing radiation exposure, patient anxiety, unnecessary biopsies, and costs.

Adult↗

Primary gallbladder carcinoma: imaging findings in 50 patients with pathologic correlation.

Different diagnostic imaging modalities [contrast cholangiography, ultrasonography, and computed tomography (CT)] in a large group of patients with proven gallbladder carcinoma are reviewed. Noninvasive cross-sectional imaging methods strongly correlated with the different gross pathologic types of gallbladder carcinoma. The most common observed type was a mass replacing the gallbladder (39%). Other types observed either by sonography and/or CT were a focal/diffuse gallbladder wall thickening and the presence of an intraluminal polypoid mass. Despite the improvement in several imaging modalities, most of the preoperatively diagnosed gallbladder carcinomas were in advanced stage (84%). A combined approach using noninvasive diagnostic methods and percutaneous aspirative biopsies may reduce the number of explorative laparotomies in the final diagnosis of gallbladder carcinoma.

Aged↗

Evolution of a case of lung plasma cell granuloma.

Plasma cell granuloma, on lung inflammatory pseudotumour, is a localized benign proliferation of plasma cells and mesenchymal cells. We report the case of a 45 yr old male, who first presented with mild pain in the left side of the chest. Chest radiography was normal. Eight weeks later he had more pain and an opacity in the left and lower zones of his left chest. After another 7 weeks he had fever and cough with yellowish-green sputum. Chest X-ray then showed a round density in the left upper lobe. The final diagnosis was established after thoracotomy histological examination.

Granuloma, Plasma Cell↗