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Biomedical subjects

T Flam

Publications and source records attributed to T Flam.

88 records · Page 5Linked to original sources

Laser lithotripsy of ureteral calculi: initial experience with a new pulsed dye laser.

Thirty-two patients with ureteral calculi ranging in size from 5 x 5 to 12 x 18 mm underwent lithotripsy with a new pulsed dye laser (Pulsolith, TMI). In 24 cases, the patients were entirely free of stones following laser lithotripsy alone, or with adjunctive stone basket removal. There were three instances of equipment failure and five calcium oxalate monohydrate stones that did not respond to laser energy.

Calcium Oxalate↗

[Palliative diversion using an autostatic ureteral stent after endoscopic resection of the ureteral meatus in T4 pelvic tumors].

Seven patients with renal failure secondary to bilateral ureteric obstruction by pelvic carcinoma underwent palliative urinary diversion. In 3 cases, an autostatic ureteric stent was inserted after endoscopic resection of the trigone invaded by the tumour in the presumed zone of the ureteric meatus, and retrograde catheterisation of the ureter. This method has very limited indications, but may improve the comfort of survival of certain patients.

Adenocarcinoma↗

[Ureteral endometriosis].

Endometriosis, initially believed to be a gynecologic disease, occasionally involves the urinary bladder, and less frequently the ureters. Use of ureteral stents with an appropriate hormonal treatment can obviate the need for open surgery.

Adult↗

[Treatment of epidermoid carcinoma of the penis].

Epidermoid carcinoma of the penis is a rare type of cancer. Treatment of the primary lesion consists of amputation, although curietherapy can be effective in some cases as a conservative treatment. The prognosis is determined by the presence of absence of lymph node invasion, but the therapeutic strategy to be used when invaded lymph nodes are present remains controversial. Lymph node dissection is the only effective treatment of metastatic adenopathy, but its high morbidity rate limits its indications.

Adult↗

[Rigid and flexible ureteroscopy. Apropos of 200 consecutive cases].

191 patients underwent a total of 200 ureteroscopies. Indications for these were as follows: ureter stones (172 cases); ureteral anomalies undiagnosed by other methods (20 cases); therapeutic ureteroscopy (8 cases). Stones: ureteroscopy for stones was carried out using either a rigid instrument (156 cases) or a flexible ureteroscope (16 cases). The localization of the stones was pelvic (123 cases), iliac (18 cases) or lumbar (10 cases). The stones were either removed directly using the basket under visual control (74/139 cases), or removed by ultrasonic/laser fragmentation (65/139 cases). As regards the rigid ureteroscope, success rates were 89% (139/156); 15 patients required additional therapy. Repeated ureteroscopic interventions always provided positive results. As concerns flexible ureteroscopy, we only had one positive result; 15 failure cases warranted repeated additional treatments. In three instances, failure with flexible ureteroscopy was corrected by using the rigid device during the same surgical period. We observed a single case of major complication in this series, i.e., a laterovesical urinoma which necessitated surgical drainage and was linked to the lack of ureteral drainage following ureteroscopy. Diagnostic ureteroscopic examinations: in 20 instances, ureteroscopy allowed to diagnose with precision the ureteral abnormality. No complication was reported following diagnostic ureteroscopy. Therapeutic ureteroscopy: such interventions were carried out to introduce a guide into the renal cavities (3 cases); to remove a double J stent, the lower extremity of which had moved up into the ureter (3 cases); or to carry out endoscopic ureterotomy (2 cases). Ureteroscopy is a safe and reliable method for the treatment of ureteral stones, and more particularly of stones localized in the distal part of the ureter.(ABSTRACT TRUNCATED AT 250 WORDS)

Cystoscopes↗

[Urogenital tumors and HIV-1 infection].

Four patients with solid genito-urinary tumors and HIV 1 infection have been treated in our institution over the last 2 years, including 2 with seminoma, 1 with renal adenocarcinoma and 1 with renal angiosarcoma. All had severely impaired immunity with a low CD4 level. Three had or developed a true AIDS syndrome according to the WHO and CDC criteria (1988). The remaining patient was seropositive and died less than 3 months following the diagnosis of renal angiosarcoma, he is the first reported case of renal sarcoma in a patient infected with HIV 1. Two patients were homosexuals and the other 2 were drug addicts. Along with other reported cases, our cases may underline the association between depression of immunity due to HIV and onset of solid genito-urinary tumors.

Acquired Immunodeficiency Syndrome↗

[Extracorporeal lithotripsy as the primary procedure in the treatment of large kidney calculi].

Extracorporeal shock wave lithotripsy (ESWL) as primary treatment for large renal stones has been evaluated in this clinical study of 55 patients. Patients were treated using the Dornier HM-3 lithotripter. Twenty-one (38%) patients presented with a stone burden greater than 4 centimeters. Nineteen patients had "steinstrasse", of which 8 had to undergo a secondary procedure. Sixteen (29%) patients had no residual stone, 5 had clinically non significant stones and 34 had clinically significant stones. Out of the 15 patients who underwent a second ESWL, only 2 were rendered stone-free. In this study, ESWL was not found to be a satisfactory treatment for large renal stones.

Endoscopy↗

Reversible hydronephrosis in the rat: a new surgical technique assessed by radioisotopic measurements.

A new technique for experimental reversible hydronephrosis in the rat was developed. A noninvasive radioisotopic investigation, using Tc-99m dimercaptosuccinic acid, permitted sequential assessment of the separate renal function at different stages of the study. After 1 week of unilateral ureteral obstruction, reversibility was obtained by the removal of the obstructive device. Ten days after the obstruction release, the ipsilateral kidney had returned to 71 per cent of its preligation uptake value. Histological findings demonstrated the reversibility of the surgical obstruction.

Animals↗

[Prostatic brachytherapy: an alternative therapy. Review of the literature] .

Radical prostatectomy remains the 'golden standard' therapy for localized prostate carcinoma for patients with a survival rate of more than ten years. However, because of the complications inherent in this surgical procedure, prostatectomy is presently increasingly challenged by various radiotherapy procedures. In the last decade, more sophisticated conformal therapy techniques have been proposed for prostate cancer patients. In parallel, for highly selected patients, brachytherapy is being promoted by an increasing number of medical centers. In fact, brachytherapy techniques for prostate cancers can be traced back to 1911, but recently developed techniques offer reliability and reproducibility, with satisfactory results in terms of tumor control and reduced toxicity, in selected patients. We present here the different techniques that are available today in prostate cancer brachytherapy.

Brachytherapy↗

[Advances in surgical techniques and results of radical cystectomies for bladder cancer. 106 patients].

AIM OF THE STUDY: Retrospective analysis of result of radical cystectomy at Cochin Hospital. PATIENTS AND METHODS: We report the results of a 106 patients series treated by radical cystectomy for bladder carcinoma after a 5-year period follow-up. RESULTS: The extent of the tumour invasion according to pathological analysis was: pT1 or less: 26%, pT2 and pT3a: 33%, pT3b and over: 41%. Morbidity rate was 19% with a 7.5% reintervention rate. Long term complication rate was 31%, concerning essentially ureteral stenosis. A local recurrence or distant metastasis occurred in 35% of patients. Local recurrence rate was 10.7%. Cancer specific survival rates were 88%, 81% and 42% for pT1, pT2-pT3a, and pT3b patients respectively. CONCLUSION: The present results confirm that radical cystectomy is the most effective curative treatment for invasive bladder carcinoma.

Adult↗

[The treatment of patients with ureteral calculi by ureteroscopy and intracorporeal lithotripsy].

Ureteroscopy with endocorporeal urinary stone lithotripsy (EUSL) implies an "in situ" stone fragmentation including or not a basket extraction of the fragments. EUSL needs three conditions: ureteronephroscopy (antegrade or retrograde), sources of energy (ultrasonic, electrohydraulic, laser), extraction devices (basket, grasping forceps). The paper reports the data on 120 ureteral stones treated by ureteroscopy and laser lithotripsy with an overall effect of 84%.

Endoscopes↗