Biomedical subjects

T Flagstad

Publications and source records attributed to T Flagstad.

12 recordsLinked to original sources

PubMed1981

Zinc absorption in cattle with a dietary picolinic acid supplement.

The effect of picolinic acid and hydroxyquinolines in intestinal zinc absorption of cattle was studied. In contrast to reports of the absorption in rat and in man, picolinic acid did not enhance zinc absorption in cattle. In two calves suffering from Adema disease, the bovine parallel to Acrodermatitis enteropathica, hydroxyquinoline supplementation resulted in an increase in intestinal 65Zn absorption, while picolinic acid had no such effect. The results may indicate a difference in the zinc absorption mechanism between cattle and other species.

Acrodermatitis↗

PubMed1977

Intestinal absorption of 65 Zinc in A46 (Adema disease) after treatment with oxychinolines.

In two calves with the genetic defect A46 (Adema disease) intestinal absorption of 65Zn was increased during a period of oral treatment with oxychinolines. Oral supplementation with zinc oxide resulted in extremely high plasma zinc concentrations and a moderate increase in 65Zn absorption.

Administration, Oral↗

PubMed1976

Lethal trait A 46 in cattle. Intestinal zinc absorption.

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Animals↗

PubMed1976

Hereditary zinc deficiency (Adema disease) in cattle, an animal parallel to acrodermatitis enteropathica.

Adema disease and acrodermatitis enteropathica, two parallel syndromes in calves of Friesian descent and in man, are described. Both are congenital zinc deficiency disorders with a lethal course if left untreated. Complete recovery follows oral zinc therapy. Symptoms and findings are set out in Table I. Diseased calves may serve as animal models for further studies on acrodermatitis enteropathica and the biological role of zinc.

Acrodermatitis↗

PubMed1974