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Biomedical subjects

T F Oltmanns

Publications and source records attributed to T F Oltmanns.

At least 19 recordsLinked to original sources

Psychometric analysis of racial differences on the Maudsley Obsessional Compulsive Inventory.

Black university students scored significantly higher than White students on the Maudsley Obsessional Compulsive Inventory (MOCI). They tended to endorse more Cleaning and Checking subscale items in the pathological direction. Subsequent analyses examined whether this finding is a reflection of valid group differences in the prevalence of OCD or a psychometric artifact. Structured interviews were conducted to determine the correspondence of MOCI scores with OCD diagnoses. The race difference in endorsement frequency on the MOCI did not extend to OCD diagnoses. The MOCI scores showed modest predictive validity in Whites, but they did not predict interview-based diagnoses in Blacks. Multivariate item response theory was then employed to examine race differences in the Cleaning and Checking subscales. Equivalent item discrimination parameters fit the data for Black and White participants for both subscales. A more restrictive model in which relative item difficulties were also constrained to be equal for Black and White participants did not fit. This interaction between race and item difficulty suggests that the items do not have equivalent psychometric properties in Blacks and Whites.

Adolescent↗

Recollections of conflict with parents and family support in the personality disorders.

This study examined the relationships between personality disorders and retrospective reports of family support and conflict with parents. Participants were 798 United States Air Force recruits who were participating in a larger program of research on the peer assessment of personality disorders. Correlational analyses revealed consistent but modest associations between personality disorder features and both measures of family adversity. Borderline, antisocial, and paranoid features maintained small, unique associations after controlling for the general component of personality disorder. Further analyses, however, showed that differences among the correlations between personality disorder traits and family adversity measures account for little explained variance. In general, it does not appear that individual personality disorders have unique relations with retrospective reports of family adversity. Instead, the relation between personality disorders and family adversity seems to depend on a component common to all personality disorders.

Adolescent↗

Peer assessment of personality traits and pathology in female college students.

Assessment procedures for personality disorders (PDs) typically rely on self-reports, even though some people with PDs may be unable to view themselves realistically or are unwilling to report socially undesirable traits. Close associates may provide important information regarding the presence of PD traits. Peer nomination is a reliable and valid assessment procedure that can be adapted to the study of PDs for research purposes. This study focused on characteristic features that define narcissistic, dependent, and obsessive-compulsive PDs using information collected from both self and others in a nonclinical sample of women. It was designed to identify specific areas of agreement and discrepancy between self-report and peer assessment in the measurement of characteristic features of these disorders.

Adult↗

Emotional experience and expression in schizophrenia and depression.

The emotional responses of schizophrenic, depressed, and normal subjects and whether differences in the emotional responding of these groups depended on how emotional responses were elicited or measured were examined. Twenty-three blunted and 20 nonblunted schizophrenics, 17 unipolar depressed subjects, and 20 normal subjects were exposed to a series of affect-eliciting stimuli. The stimuli varied in valence (positive vs. negative) and in level of cognitive demand. Subjects reported their subjective experiences, and their facial expressions were videotaped. Blunted schizophrenics were the least facially expressive, although their reported subjective experiences did not differ from those of the other groups. The nonblunted schizophrenics were more responsive than the depressed subjects to the positive stimuli, although the two groups did not differ in their clinical ratings of affective flatness.

Adult↗

Hedonic capacity in schizophrenics and their twins.

Audio-taped interviews recorded in the Gottesman-Shields schizophrenic twin series (17 pairs of identical twins, 14 pairs of fraternal same-sex twins, and 12 unpaired twins) were rated for level of hedonic capacity. Schizophrenics who were not hospitalized at the time of their interview were rated significantly lower (more impaired) on hedonic capacity than their normal co-twins. A significant negative correlation was also found between hedonic capacity and severity of illness. Hedonic capacity was found to be genetically influenced, although it appeared to be less heritable than the global diagnosis of schizophrenia. These results are consistent with Meehl's suggestion that reduced hedonic capacity is a heritable personality trait which potentiates the development of schizophrenia among those who are genetically predisposed to the disorder. The results suggest that anhedonia is not a phenotypic vulnerability marker for schizophrenia.

Affective Symptoms↗

Mental health needs of the chronically mentally ill elderly.

The treatment histories and current social, financial, and clinical status of 111 chronically mentally ill (CMI) persons over the age of 60 were examined. Information was obtained from Ss, family, mental health records, and mental health professionals familiar with Ss. Psychiatric symptoms were observed in 74% of Ss. Many Ss experienced long periods without acute episodes of illness. Recurring episodes eventually appeared in most Ss, however, and ongoing deficits in daily functioning and social contacts were prototypical. Two thirds of the Ss were living in the community, relying heavily on family contacts; the rest lived primarily in nursing homes (23.4%) or psychiatric hospitals (7.2%). Social support was the best predictor of level of functioning. Findings suggest that failure of CMI elderly to use mental health services is not due to lack of need. Mental health services currently do not appear to be meeting the needs of this population.

Activities of Daily Living↗

Rating affective flattening from videotaped interviews.

Semistructured interviews with 28 schizophrenic patients were videotaped. The affective flattening section of the Scale for the Assessment of Negative Symptoms (SANS) was rated after each interview. At a later date, each videotape was rated by three raters as well as the interviewer. Reliability was estimated within and across rating conditions by intraclass correlation. Comparison of reliability scores across rating conditions indicated that the videotape medium had little effect on the ability of raters to rate affective flattening similarly.

Humans↗

Poverty of speech in schizophrenia and depression during in-patient and post-hospital periods.

Poverty of speech, a prominent feature of the negative symptom construct in schizophrenia, was assessed longitudinally in 12 schizophrenic and 13 depressed subjects at hospital admission and about seven months after discharge in order to evaluate hypotheses concerning course and diagnostic specificity. Multiple measures of the poverty of speech construct were employed, including both clinical and quantitative indices. During the in-patient period, poverty of speech was more pronounced among depressed than schizophrenic subjects. Examination of this specific negative symptom across in-patient and follow-up evaluations indicated that poverty of speech increased among schizophrenic subjects, but remained relatively stable or declined among depressed subjects. These results suggest that the processes underlying poverty of speech may differ in schizophrenia and depression.

Adult↗

Anhedonia and emotional responses to affect evoking stimuli.

The purpose of the present study was to determine whether individuals with unusually high scores on the Scale for Physical Anhedonia (Chapman et al. 1976) would differ from average scorers in their emotional responses to affect-evoking stimuli. Ten male and ten female anhedonics, as well as ten male and ten female control subjects, were each shown brief filmclips that were expected to elicit emotional responses. The subjects' facial expressions were videotaped while they watched the filmclips, and they also completed adjective checklists describing how they felt while watching them. The anhedonics and nonanhedonics did not differ in their self-reports of emotional experience, nor did they differ in their facial expressions of emotion while viewing the filmclips. Compared to men, women reported experiencing more emotion, and their facial expressions also indicated greater responsiveness.

Affective Symptoms↗

Communicability and thought disorder in schizophrenics and other diagnostic groups. A follow-up study.

To evaluate qualitative differences in the nature of thought disorder, the 'cloze' procedure and the Scale for the Assessment of Thought, Language and Communication were used to compare speech samples from schizophrenic, depressive, manic, schizo-affective and normal subjects at two different times. At the acute phase, thought-disordered subjects (schizophrenics, manics and schizo-affectives) were less communicable than non-thought-disordered subjects (depressives and normals). Communicability increased with remission of the more flagrant features of disturbance. Comparison of the thought-disordered diagnostic groups in the rate and pattern of remission of specific features of thought disorder indicated that factors reflecting goal-disrupted cognition distinguished the groups.

Adult↗

The need to relate cognitive deficits to specific behavioral referents of schizophrenia.

The implicit rationale for many cognitive studies of schizophrenia hinges on the recognition that verbal communication generated by patients with this disorder is often elusive or difficult to comprehend. This observation has led to the inference that a cognitive dysfunction, which mediates the production of discourse failure, is characteristic of schizophrenia. Unfortunately, most investigators have chosen to examine this type of hypothesis by comparing heterogeneous groups of schizophrenic patients (without regard to whether they exhibit verbal communication impairment) with various control samples; they have not studied the association between cognitive processes and specific schizophrenic symptoms. Data are presented from two studies indicating that such relationships, even when highly plausible, cannot simply be presumed. In both studies, one with adults suffering from schizophrenia and the other with children at risk, a laboratory measure of referential communication failed to be strongly related to language disorder. These data suggest that future investigators should specify the features of schizophrenia that are expected to correlate with their laboratory measures and empirically evaluate these relations.

Adult↗

Rating verbal communication impairment in schizophrenia and affective disorders.

Audio recordings of interviews with 42 psychiatric patients (10 schizophrenic, 11 manic, 11 schizoaffective, and 10 depressive patients) and 10 hospitalized orthopedic patients were rated for the presence of verbal communication impairment using the system developed by Andreasen. The definitions of some categories required additional qualifying statements before agreement could be reached on their meaning and applicability in specific circumstances. Nevertheless, the results indicate that the scales can be used reliably by carefully trained, nonprofessional raters. Significant differences were found between diagnostic groups with regard to the frequency and severity of some categories of communication impairment, but the general pattern of results supports previous suggestions that these problems are not pathognomonic of schizophrenia. Based on our experience, we suggest a few changes that might be helpful to other investigators, both in the procedures used for obtaining samples of speech and the definitions of subcategories of verbal communication impairment.

Child↗

Predictability as an index of impaired verbal communication in schizophrenic and affective disorders.

The cloze procedure was used to examine predictability in speech samples from schizophrenic, depressive, manic, schizoaffective and normal subjects. Each speech sample was also rated for particular indices of thought disorder using the Andreasen Scale for the Assessment of Thought, Language and Communication. Schizophrenics were found to be less predictable than other patient groups or normals. Depressives were found to be the most predictable. Correlational analyses of cloze scores and specific thought disorder ratings suggest that reduced predictability is associated with traditional indicators of thought disorder.

Adolescent↗