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T E Watts

Publications and source records attributed to T E Watts.

23 records · Page 2Linked to original sources
PubMedDate not supplied

The role of some risk factors of exposure to malaria in determining the outcome of the immunofluorescent antibody test in an urban population.

Data obtained previously were analysed to assess the relative importance of variables which relate to the risk of exposure to malaria in explaining the level of indirect fluorescent antibody (IFAT) reactions observed among the urban study population. In the analysis specific activities, notably travelling out of the main towns, season when out of the main towns, length of period since having been out of the main towns, and history of having had malaria in the last year, were of help in predicting the level of IFAT reaction. Sensitivity and specificity values of history of malaria, history of having been out of the main towns, and serological results were higher in older people in both periods and were highest in the March-April 1985 survey period.

Adolescent↗
PubMedDate not supplied

Malaria in an urban and a rural area of Zambia.

Children in Lusaka and in a rural area in central Zambia were examined during November 1984 and April 1985 to assess the effect of urbanization on malaria transmission. Of 423 urban children examined in November, 2.4% had scanty parasitaemia, and low titres of malarial antibodies were found in 46%. These proportions increased in April to a parasite rate of 10.3% and malaria antibodies were detected by indirect fluorescent antibody tests (IFAT) in 62%. The presence of malaria antibodies was positively associated with journeys outside the main towns. Examination of paired sera from the 2 periods showed an association between a history of malaria and an increased antibody titre, but failed to show an association between travel outside the main towns and conversion from a negative to a positive IFAT. The spleen rate in children under 15 years old in Lusaka was 3%, indicating hypoendemic malaria. In rural children the parasite rate was 10% and 27% in the 2 seasons, respectively, and over 97% of the children had malaria antibodies. The spleen rate was 20%, indicating mesoendemic malaria. It is concluded that there is only low transmission of malaria in Lusaka so that many people do not develop resistance and are therefore at risk of severe attacks if they do become infected. Possible measures to protect the urban population are discussed.

Adolescent↗