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Biomedical subjects

T E Lackner

Publications and source records attributed to T E Lackner.

27 records · Page 2Linked to original sources
PubMed1983

Lidocaine stability in cardioplegic solution stored in glass bottles and polyvinyl chloride bags.

The stability of lidocaine hydrochloride in buffered cardioplegic solutions stored in glass and polyvinyl chloride bags was studied. Concentrations of lidocaine (incorporated as the hydrochloride salt) were measured in buffered cardioplegic solutions containing potassium chloride, sodium bicarbonate, dextrose, and sodium chloride. Solutions were stored at 22 +/- 2 degrees C and 4 degrees C in glass bottles and 500-ml and 250-ml polyvinyl chloride (PVC) containers; some 250-ml PVC bags were underfilled to study the effects of varying surface area-volume ratios. Lidocaine concentrations were measured using a homogeneous enzyme immunoassay (EMIT, Syva Corporation) on days 0, 1, 2, 7, and 21. Lidocaine concentrations decreased significantly in all PVC bags stored at 22 degrees C and in underfilled PVC bags stored at 4 degrees C. Lidocaine loss in PVC bags appeared to result from sorption. It is concluded that lidocaine is stable in cardioplegic solutions when these are refrigerated and stored in glass containers or filled large-volume PVC bags for 21 days.

Drug Combinations↗
PubMedDate not supplied

Short- and long-term retention of a nursing home education program on metered-dose inhaler technique.

OBJECTIVE: To evaluate an education program on metered-dose inhaler (MDI) technique designed for nurses and trained medication aides (TMAs). DESIGN: The education program included a handout, a lecture incorporating a videotape on correct inhaler and device technique, and hands-on experience with placebo inhalers. The participants' ability to verbalize and demonstrate correct MDI technique was assessed by the same two-person teams before, immediately after, and two months after the program. SETTING: Five nursing homes. PARTICIPANTS: Fifty-six nurses and TMAs practicing in nursing homes. MAIN OUTCOME MEASURES: Learning and retention. RESULTS: The participants' mean (+/- SD) verbal and demonstration scores increased immediately after the program by 68 +/- 18 points for verbalization and 47 +/- 16 points for demonstration. The participants were always better at demonstrating than verbalizing MDI technique. The participants' baseline verbal and demonstration scores correlated with the amount learned. Learning was influenced by the individual nursing home (verbal and demonstration) and personal use (demonstration only), but not by academic degree, previous training, past instruction of a patient, or current care of a patient who was receiving inhaler therapy. After two months, the scores were lower than immediately after the program test by 0-92 points for verbalization and 10-80 points for demonstration; however, the mean scores were still significantly greater (p less than 0.05) than the baseline scores. Retention of knowledge on the correct technique was greater for the demonstration component. Retention was influenced only by the nursing home in which the participant worked, and not any of the other variables. CONCLUSIONS: Our structured education program significantly improved inhaler technique; however, to maintain retention of the material, the program should be frequently repeated.

Clinical Competence↗