Biomedical subjects

T E Hansen

Publications and source records attributed to T E Hansen.

At least 37 records · Page 2Linked to original sources

PubMed1989

[Soft intraocular lenses].

Hard intraocular polymethylmethacrylate (PMMA)-lenses have been implanted following cataract extractions since 1949, and their good properties are well proven. Soft intraocular lenses have only been implanted since 1976. Their chemical and physical properties, advantages and disadvantages are discussed with reference to the well known PMMA-lenses. In the short term the patients obtain the same visual acuity with soft intraocular lenses as with hard intraocular lenses, and it is the impression, that the soft lenses are more tissue compatible, but more prolonged follow up is required.

Aged↗

PubMed1988

Posterior capsule fibrosis and intraocular lens design.

Four different posterior chamber lens designs were used in 1,845 consecutive, unselected extracapsular cataract extractions performed over a 31-month period in Vejle, Denmark. Ninety-seven eyes (5.3%) required a posterior capsulotomy during a postoperative observation period ranging from two to 32 months. At 16 months postoperatively, the cumulative capsulotomy rate was 7.1% with plano-convex anterior lenses, but only 1.7% with meniscus lenses and 1.8% with continuous ridged lenses. These results suggest that close contact between the posterior capsule and the optic could induce early posterior capsule opacification.

Cataract Extraction↗

PubMed1988

Risk factors for drug-induced parkinsonism in tardive dyskinesia patients.

Using multivariate statistical analyses, the authors identified risk factors for development of drug-induced parkinsonism (DIP) in 66 tardive dyskinesia (TD) patients. Older age, recent use of neuroleptics, shorter duration of past neuroleptic exposure, and severity of TD were associated with increased risk of DIP. The clinician should devise treatment strategies in anticipation of the occurrence of DIP regardless of the presence or absence of TD, especially in older patients. New models for the pathophysiology of the two disorders are needed.

Adult↗

PubMed1987

A prospective study of intraocular pressure four months after extracapsular cataract extraction with implantation of posterior chamber lenses.

Sixty-six consecutive cases of extracapsular cataract extraction (ECCE) and sulcus implantation of a posterior chamber lens had intraocular pressure (IOP) measurements recorded four months postoperatively. These results were compared to the fellow unoperated eyes, as well as to a group of 64 patients, whom we reported previously, who had intracapsular cataract extraction (ICCE) and implantation of an anterior chamber lens. The ECCE and posterior chamber lens group demonstrated a significant reduction in the IOP of the operated eye after four months (P less than 0.001), with none of the patients having an IOP greater than 20 mm Hg. No significant IOP change could be demonstrated in the fellow eye (0.1 less than P less than 0.2). We found a significant difference between the ECCE and ICCE groups in the IOP of the operated eye (P less than 0.001).

Aged↗

PubMed1987

Prospective study of intraocular pressure 2 1/2 years after intracapsular cataract extraction and implantation of a semiflexible anterior chamber lens.

Fifty-one patients available for a 2 1/2 year follow-up after intracapsular cataract extraction and implantation of the semiflexible McGhan/3M, style 70 anterior chamber lens were evaluated for intraocular pressure (IOP). No significant change in the IOP could be demonstrated despite progression of iris-like tissue adhesions between the iris and lens haptics at or close to the trabecular meshwork. Four eyes (7.8%) had IOPs greater than or equal to 22 mm Hg without medication, and four other eyes used timolol eyedrops with subsequent IOPs less than or equal to 18 mm Hg. Eight eyes (15.7%) demonstrated an IOP increase greater than or equal to 25% over baseline pressures.

Anterior Chamber↗

PubMed1987

Morphological changes and lens position 2 1/2 years after intracapsular cataract extraction with implantation of a semiflexible anterior chamber lens. A prospective re-examination.

Morphological changes and lens position were examined in 51 patients 25 to 38 (mean 30) months after intracapsular cataract extraction (ICCE) with implantation of the semiflexible, 3M, style 70, anterior chamber lens. Morphological changes presumably associated with the ICCE proper were: iris transillumination defects (68.6%), rupture of anterior hyaloid membrane (20%), detachment of posterior vitreous (42.9%) and anterior synecchiae (13.7%). The implant-related morphological changes were caused by iris tucking (19.6%), small, mobile lenses causing endothelial disturbance (9.8%), iris-haptic adhesions and progressive ovalling of pupillary form. The present morphological changes were compared with a previously published examination of the same patients performed 4 months after surgery: 9 eyes without tissue changes around the lens feet at the previous follow-up now had iris-haptic adhesions involving from 1 to 4 lens feet. In 8 eyes the iris-haptic adhesions had progressed. Compared with the previous examination the fraction of eyes with tissue changes at the lens feet had risen from 47.1 to 64.7%, while the number of eyes with oval pupils had increased from 54.9 to 80.4%. Contact between lens haptic and iris root seems to constitute a constant stimulus for structural changes of the iris.

Aged↗

PubMed1986

Complications and visual outcome 4 months after implantation of the semiflexible McGhan/3M, style 70, anterior chamber lens. A prospective study.

A report is given of visual outcome and intraocular complications in 64 patients 3-8 months after implantation of anterior chamber lens. 80% had a final visual acuity of 0.50 or better. Visual acuity below 0.50 could in most cases be related to pathological findings in the eye independent of implant. Pupillary block was found in 4 cases (6%), and at re-examination they all had gonioscopic changes. The mechanism of pupillary-block-glaucoma with IOL lens implantation and measures to meet this is discussed. Gross tucking was found to pre-dispose to chronic inflammation. Cystoid macular oedema (3%) and retinal detachment (2%) was found without obvious relationship to gonioscopic changes.

Aged↗

PubMed1986

Morphological changes after extracapsular cataract extraction with implantation of posterior chamber lenses. A prospective clinical study.

Morphological changes and lens position were examined in 66 patients 3 to 5.5 (mean 4) months after extracapsular cataract extraction with intended implantation of posterior chamber lenses in the ciliary sulcus. Important findings were: capsulotomy-requiring secondary cataract (3%), iris-lens synecchiae (18%), iris-capsule synecchiae (14%), pupillar capture (2%) and haptic-malposition (17%). The lens optic was slightly decentered in 33%. The internal anterior chamber depth was measured with optical pachymetry and averaged 3.5 mm (range 2.3-4.5 mm). The central distance between the posterior lens surface and the posterior capsule (LPCD) was measured pachymetrically and averaged 0.14 mm (range 0-0.6 mm).

Anterior Chamber↗

PubMed1986

Intraocular pressure in the first days after implantation of posterior chamber lenses with the use of sodium hyaluronate (Healon).

Intraocular pressure (IOP) was measured before and 6, 24, 48 and 72 h after extracapsular cataract extraction with implantation of a posterior chambers lens in 3 groups of patients. Group I (30 patients): Sodium hyaluronate (Healon) was used during anterior capsulotomy and lens implantation and was aspirated at the end of surgery. Group II (22 patients): Healon as in group I + 500 mg acetazolamide at the end of surgery. Group III (17 patients): BSS and/or air was used instead of Healon during surgery. In all groups statistically significant rises in IOP after 6 h were followed by significant falls in the remaining post-operative period. The rise and subsequent fall in IOP was significantly greater in group I than in group III. Acetazolamide in group II did not prevent excessive rises in IOP. Aspiration probably shortens the period of Healon-induced hypertension. We recommend a meticulous aspiration of Healon at the end of surgery.

Acetazolamide↗

PubMed1986

Complications and visual outcome 4 months after extracapsular cataract extraction with implantation of posterior chamber lenses. A prospective clinical study.

Sixty-seven patients were examined 3 to 5 1/2 (mean 4) months after intended extracapsular cataract extraction with implantation of the 3 M, style 83, posterior chamber lens. A visual acuity greater than or equal to 0.5 was recorded in 58 (86.6%) of the patients. The complications were: one (1.5%) case of acute iritis, one case of pupillary capture and two (3.0%) cases of capsulotomy-requiring early secondary cataract. There were no posterior segment complications. None of the patients were treated with anti-glaucomatous medication, and none had intraocular pressure above 20 mmHg. Pre-operatively, biometry was performed, and the SRK-formula was employed in estimating the post-operative spherical equivalent refraction: The actually measured refraction differed less than 2 diopters from the predicted refraction in 84.5% of the cases.

Cataract Extraction↗

PubMed1986

Tremor and tardive dyskinesia.

A retrospective review of charts for the prevalence of tremor in patients with tardive dyskinesia revealed that 10% of 232 patients with a diagnosis of tardive dyskinesia also had parkinson-like tremor. No demographic or clinical risk factors for this tremor could be identified. The body areas affected by tremor are described, and it is suggested that tremor occurring in areas other than the wrist may pose a problem in differential diagnosis of patients with tardive dyskinesia. Changes in tremor and tardive dyskinesia after alterations in medication dose are reported, and recommendations for management are given.

Antipsychotic Agents↗

PubMed1985

Assessment of tardive dyskinesia using the Abnormal Involuntary Movement Scale.

Over a 10-month period, 33 patients with tardive dyskinesia (TD) were evaluated with the Abnormal Involuntary Movement Scale (AIMS) simultaneously and independently by two experienced and two inexperienced raters. The experienced raters generally had higher levels of agreement and their scores were more consistent over time. It is concluded that experience with TD influences AIMS inter-rater reliability and that it is useful to differentiate TD movements into the dimensions of quality, frequency, and amplitude, dimensions not currently used in the AIMS. The usefulness and difficulty of developing more specific guidelines for AIMS ratings are discussed.

Ambulatory Care↗

PubMed1985

Intraocular pressure 4 months after implantation of the semiflexible McGhan/3M, style 70, anterior chamber lens. A prospective study.

Sixty-four patients were consecutively operated for senile cataract with implantation of the semiflexible McGhan/3M, style 70, anterior chamber lens. Intraocular pressure (IOP) was measured one day prior to the operation, 6 days and 3-8 months (mean 4 months) after the operation, and gonioscopy was performed one day prior to and 4 months after the operation. A significant fall in IOP was found in the operated eye 6 days after surgery. No significant change in IOP was found 4 months after surgery, neither in the operated eye nor in the non-operated fellow eye. Iris tucking seemed to have no influence on the post-operative tension, while a significant rise in IOP was found in 13 eyes with adhesions between the iris and lens haptics as the only abnormal gonioscopic finding.

Aged↗

PubMed1985

Gonioscopy after implantation of the semiflexible McGhan/3 M, style 70, anterior chamber lens. A prospective study.

Gonioscopy was performed in 64 patients 3-8 (mean 4) months after intracapsular cataract extraction with implantation of the semiflexible McGhan/3 M, style 70, anterior chamber lens. Iris tucking was present in 19 (30%) eyes. Iris-haptic adhesions (strands of iris-like tissue encircling the lens feet) were present in 24 (38%) eyes. Absence of iris tucking was statistically significantly (P less than or equal to 0.05) related to surgical expertise, while the occurrence of iris-haptic adhesions was independent of surgical experience. Pupillar deformation, usually an elongation in the axis of the implant, was present in 50%. The absence or presence of an abnormal gonioscopy could not with certainty be deduced from the form of the pupil. The majority of gonioscopically visible pathological changes in the chamber angle were located posterior to the trabecular meshwork.

Aged↗

PubMed1985

Intraocular pressure in the first days after implantation of the semiflexible McGhan/3 M, style 70, anterior chamber lens.

Intracapsular cataract extraction employing a corneal incision and with implantation of the semiflexible McGhan/3 M, style 70, anterior chamber lens was performed in a group of 25 patients with senile cataract. Intraocular pressure (IOP) was measured prior to and daily in the first 4 days after the operation. IOP was slightly, but significantly (P less than or equal to 0.05) lower in the observed post-operative period as compared to the pre-operative measurement. Similar results have previously been found after cataract extraction with an identical technique, but without lens implantation. This probably means that early post-operative intraocular homeostasis with respect to IOP is unaffected by the implantation of this type of lens. The fine regulation of early post-operative IOP is probably related to the fact that the described surgical technique usually is associated with only minor gonioscopically visible changes of the trabecular meshwork.

Aged↗

PubMed1984

Gastric motility following peroral administration of ranitidine. A double-blind comparison with placebo.

Gastric pressure recordings were performed in 17 healthy persons, 21-25 years of age with a fiberoptic device. After an overnight fast two calibrated transducers fixed 8 cm between censors were localized to the antrum of the stomach by fluoroscopy. Ranitidine (150 mg) and placebo tablets were given perorally in the morning for two days before and on the day of the test 11/2 hours before recording in randomized order. As previously observed in the duodenum similar maximal pressure periods (MPP), of average 7 min duration and 0.6 min displacement from the proximal to the distal sensors were found without significant differences between treatments. The MPP following the ranitidine treatment occurred, however, significantly more frequently than after placebo, indicating a promotion of motility.

Adult↗

PubMed1983

A new method with fiberoptic transducers used for simultaneous recording of intravesical and urethral pressure during physiological filling and voiding phases.

A new technique using fiberoptic transducers for simultaneous registration of intravesical and urethral pressures during the physiological filling and voiding phases is described. The method, which is simple, exact and stable, was used on several patients with different urological problems. The study shows that the measurement technique and the fiberoptic transducer system are suited for clinical use.

Adult↗

PubMed1983

Posterior polymorphous corneal dystrophy of Schlichting. A clinical study on four families.

Posterior polymorphous corneal dystrophy of Schlichting was studied in 4 families. Nine persons were found with the typical lesions. Two families suggested a dominant mode of inheritance, in one of these with a penetrance less than 100%. There were 2 sporadic cases. No corneal oedema was present, and the central corneal thickness showed normal values, which means that the corneal endothelium in this dystrophy is able to maintain a normal hydrated cornea.

Adolescent↗