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Biomedical subjects

T Ducastelle

Publications and source records attributed to T Ducastelle.

42 records · Page 3Linked to original sources

[Colitis marginal to cancer. Apropos of 7 cases].

The authors report 7 new cases of colitis above a carcinoma. The study of these cases and of those reported in the literature shows the main pathological characteristics of the lesions and permits discussion of the pathogenesis. Chronic ischemia caused by an increase in intraluminal pressure above the neoplastic stenosis seems to be the main etiological factor.

Aged↗

[Anorectal stenosis caused by suppositories of dextropropoxyphene and paracetamol (Diantalvic)].

Occasionally, administration of medical substances per annum may result in serious local lesions. The authors report the case of a 58 year-old woman presenting ulcerative and stenosing lesions of the anal canal which led to abdominoperineal resection. History revealed the administration of two suppositories daily, each containing an association of dextropropoxyphene and paracetamol, during seven years because of a cervical pain. Fourteen similar cases have been found in the literature, underlining the difficulties in clinical and pathological diagnosis. The exact mechanism of these lesions remains unknown.

Acetaminophen↗

[Non lymphoid cells of the peripheral lymphoid organs. Recent morphological progress and current understanding (author's transl)].

Peripheral lymphoid organs have two groups of non lymphoid cells: that of macrophages which belongs to R. van Furth's system of mononuclear phagocytes and the one made of elements for long labelled "reticular cells". The use of electron microscopy has permitted a good understanding of these elements and a recognition of ubiquitous cells (fibroblasts, endothelial cells) and specific cells to the lymph node which seem to play a very important role in the immune reactions (interdigitated cells, reticulum cells, dendritic cells). We describe their light and electron microscopical features and histoenzymatic characters, and present the actual concept of their origin and function. The latest discoveries on their classification are reviewed and have permitted to distinguish three categories of non lymphoid cells: first the group of reticulum cells (reticulum cells and dendritic cells), second that of mononuclear phagocytes (macrophages and interdigitated cells) and third that of endothelial cells. Other elements of questionable existence or insufficiently known do not appear in this classification: dark cells, Steinman and Cohn's dendritic cells and cells containing Birbeck's granules.

Animals↗