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Biomedical subjects

T Colton

Publications and source records attributed to T Colton.

At least 91 records · Page 5Linked to original sources
PubMedDate not supplied

The distribution of intraocular pressures in the general population.

A variety of studies are reviewed in which intraocular pressure (IOP) was determined in defined, general populations. The studies exhibit a remarkably consistent pattern for the frequency distribution of IOP. The distribution conforms well to a normal curve for pressures up to 21 mm Hg, after which a distinct skewness to the right begins to appear. When the data are grouped by age and sex, the degree of right skewness intensifies with age. Mean IOP increases with age. Some studies also show higher mean levels for women than men, but not all do. The arbitrary nature of specifying upper limits of normality is stressed. In addition, the literature is reviewed concerning the arguments for a mixture of two overlapping normal (or lognormal) curves vs a continuum for the distribution of IOP.

Adult↗
PubMedDate not supplied

Seizures in bacterial meningitis: prevalence, patterns, pathogenesis, and prognosis.

Of 207 patients with acute bacterial meningitis previously reported by Dodge and Swartz, seizures occurred in 56 (27%). Most seizures began on the first or second day, and most stopped within two days. Seizures occurred most often at the extremes of life. Age-adjusted seizure frequency was greater with Hemophilus influenzae meningitis than with Streptococcus pneumoniae or Neisseria meningitidis. When seizures complicated bacterial meningitis, age-corrected mortality increased from 24% to 38%. Though seizures after recovery were infrequent (2.7% of cases), recurrences were five times more frequent in patients who convulsed acutely than in those who did not. When focal seizures accompanied focal pathology (extracranial or intracranial), the seizures were usually not lateralized to the opposite side of the body. Of factors of potential importance in causation of seizures, fever was the most important risk factor regardless of patient age.

Adolescent↗