Activity of some hydrolytic enzymes in the cells of skin exudate and in blood after pyrogen injection.
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Biomedical subjects
Publications and source records attributed to T Cichocki.
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The autopsy samples of human aortic wall were investigated to determine the structure of the inorganic deposits formed at the onset of the mineralization process. The studies were concentrated on the material for which histochemical staining of randomly selected sections did not reveal the presence of minerals. The highly mineralized human media samples as well as broad spectrum of model compounds were investigated for comparative purposes. It was found that the inorganic phase at the onset of tunica media mineralization is composed of a few compounds including octacalcium phosphate as the predominant Ca-P compound, and a Mg-compound, probably magnesium carbonate or double/triple salts containing magnesium carbonate.
Popliteal arteries from 14 individuals (17-85 y old) were investigated. The concentrations and localizations of P, S, Cl, K, Ca, Fe, Cu, Zn and Br were measured by means of PIXE and micro-PIXE methods. The presence of PO4(3-) and CO3(2-) groups was assessed using the IR technique. The amount of P and Ca increased with age approaching at places 9% and 20% and mineral deposits were detected in tunica media. At the same time an increase in the Ca/P ratio and in the crystallinity of deposits was observed. The samples from old individuals also contained more CO3(2-) groups. The concentrations and localization of Zn and Br showed artery wall layer-dependent changes. In some places of the artery wall, minerals were also found in young persons. They were not correlated with places of blood vessel branching.
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In 6 patients with chronic lymphatic leukaemia receiving subcutaneously purified calf thymus extract a greater frequency of the following processes was observed: 1) increase in the number of smooth-surface lymphocytes (T cells) in scanning electron microscopy, 2) increased number of lymphocytes forming rosettes with uncoated sheep erythrocytes, 3) increased number of lymphocytes showing high activity of acid phosphatase in cytochemical investigations.