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Biomedical subjects

T Christ

Publications and source records attributed to T Christ.

At least 37 records · Page 2Linked to original sources
PubMed1986

[A test of pressure tolerance of the optic nerve head in ocular hypertension].

VER was recorded in 7 patients with ocular hypertension while intraocular pressure was artificially elevated. Four of the patients manifested signs of vascular autoregulation, while in 3 no such signs were observed. This absence of autoregulation was also observed in primary open-angle glaucoma patients. On the basis of these first results it may be expected that the pressure compliance test will identify patients with ocular hypertension in whom damage to the optic disk is likely to occur at a later date.

Adult↗
PubMed1986

[Corneal contact time of artificial tear solutions].

In 30 subjects without ophthalmological disease the corneal contact time of a new artificial polyacrylic-based tear gel (Vidisic, produced by Dr. Mann, Berlin) was compared with a well-known artificial polyvinyl alcohol-based tear solution. The Vidisic concentration remained in the corneal tear film 7 times longer than the substance it was compared with. In a second study including 7 normal subjects and 5 patients with keratoconjunctivitis sicca, the influence of Vidisic on break-up time (BUT) and the Schirmer test was demonstrated. It was found that tear secretion improved for 2-4 hours (Schirmer test) and the stability of the tear film (BUT) improved for about 6 hours with Vidisic. These results suggest that application of Vidisic four times a day is sufficient for efficatious therapy even in cases of severe keratoconjunctivitis sicca.

Acrylates↗
PubMed1986

The 'flicker test' according to Aulhorn in the diagnosis of acute optic neuritis.

The flicker test, introduced by Aulhorn is a new simple method to detect acute optic neuritis. We examined 24 patients suffering from acute optic neuritis. 23 patients showed a pathological result. In 179 subjects (patients with other ophthalmological diseases and healthy persons) the flicker test always showed normal results. After restitution of acute optic neuritis the results of the flicker test return to normal while the visual evoked responses remain pathological in many cases. Thus the flicker test can be an efficient tool in the diagnosis and differential diagnosis of acute optic neuritis.

Acute Disease↗
PubMed1985

Autoregulation of ocular blood flow during changes in intraocular pressure. Preliminary results.

Visual evoked potentials were recorded in six normal subjects and in three patients with primary open-angle glaucoma, while intraocular pressure was artificially elevated in stepwise increases. The resulting perfusion-pressure amplitude curves in our controls showed a kink, which can be interpreted as a sign of vascular autoregulation. No kink was observed in the curves of our glaucoma patients, which we interpret as indicating a lack of vascular autoregulation in primary open-angle glaucoma.

Adult↗
PubMed1985

[Ulrich oculo-oscillodynamography: initial results in carotid stenoses].

Oculo-oscillodynamography (OODG) after Ulrich was performed in 11 patients suffering from a monolateral, hemodynamically relevant carotid stenosis identified by Doppler sonography. All of the pressure parameters which can be measured by OODG--systolic retinal, systolic ciliary, and diastolic ocular perfusion pressure--were low on the side concerned. In contrast to the already-established methods of measuring ocular perfusion--ophthalmodynamometry and ophthalmodynamography after Hager--the advantages of OODG are that it not only enables the systolic retinal pressure to be differentiated from the systolic ciliary or diastolic ocular perfusion pressure, but also permits the results of the investigation to be illustrated graphically, so that objective evaluation is possible.

Aged↗
PubMed1985

[Ocular hemodynamics in central and branch artery occlusions].

Ocular oscillodynamograms (OODG) were made in 9 patients with an occlusion of the central artery and 11 patients with an occlusion of one branch artery. While there were no pathologic findings in patients with branch artery occlusions, it was not possible to record any systolic-retinal oscillations of the pulse in patients with an occlusion of the central artery. In three cases the systolic ciliary perfusion pressure was also low owing to carotid stenosis.

Adult↗
PubMed1985

[Computer tomography in partial optic nerve avulsion].

An partial avulsion of the optic nerve was found after a blunt ocular trauma in a 34-year old-patient. For the first time it is possible to demonstrate CT exposures of such a case. The importance of this method in cases of blunt ocular trauma accompanied by hemorrhages of the anterior chamber or the vitreous is discussed.

Adult↗
PubMed1985

Flicker fusion frequency and organic syndrome in alcoholics.

Flicker fusion frequencies of 48 healthy controls and of 35 alcoholics were measured to detect possible associations between flicker fusion and signs of nonspecific brain damage, the aim of the study. FFF was statistically significantly lower in patients addicted to alcohol than in healthy subjects. Lower flicker fusion frequencies were associated with the severeness of organic psychosis as rated psychopathologically. The hypothesis that addiction to alcohol is a sign of diffuse, nonspecific, organic brain damage was discussed.

Adult↗
PubMed1984

[Influence of a barrier filter on tear film breakup time].

In 30 healthy volunteers the tear-film break-up times of both eyes were determined, comparing one eye with a cut-off filter (customarily used in fluorescein angiography (Schott OG 530, thickness 3 mm] with the common method, not using this filter, in the other eye. By using the filter the variance of observed break-up times is decreased, and the time elapsing after the administration of the dye no longer influences the break-up time significantly. The filter described here is therefore recommended for determining the tear-film break-up time.

Adult↗
PubMed1984

[Effect of various stimulation filters on tear film breakup time].

The tear break-up was determined in 30 patients with healthy eyes aged from 18 to 67 using two different types of filter combinations: (1) Schott Filter OG 530 and Schott Filter BG 12. (2) Schott Filter OG 530 and Zeiss Filter 485. In view of the filter characteristics, we expected a reduction of the variance of the tear break-up time with the second filter combination. This did not occur. There was no difference between the two filter combinations described according to the Wilcoxon Test on the 5 percent level. The reasons are discussed.

Adolescent↗
PubMed1983

[Factors influencing the variability of tear film break-up time].

Tear film break-up time was measured on 6 consecutive workdays in 6 subjects without eye disease selected at random. The reasons for the wide range of scatter in the values measured were investigated by variance component estimation. It was found that intraindividual variance is by far the most important factor influencing the overall variance of the measured values. Therefore, caution is called for when judging the stability of the precorneal tear film by the tear film break-up time in healthy individuals.

Adolescent↗