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Biomedical subjects

T Chkili

Publications and source records attributed to T Chkili.

At least 55 records · Page 3Linked to original sources

Middle cerebral artery occlusion due to hydatid cysts of myocardial and intraventricular cavity cardiac origin. Two cases.

BACKGROUND: Hemispheric strokes of hydatid origin are very rare. We describe two cases of middle cerebral artery occlusion by a cyst of cardiac origin. CASE DESCRIPTIONS: Cerebral angiography demonstrated occlusion of the initial segment of the middle cerebral artery. Myocardial and pericardial cysts were diagnosed by echography and pathological examination. Subsequent development of hydatid cysts within the necrotic area of the infarcted hemisphere suggests cerebral hydatid embolism of cardiac origin. CONCLUSIONS: In endemic areas, embolism of hydatid cysts should be considered in the diagnosis of stroke in young patients.

Adult↗

[Alexia without agraphia in the Arabic language. Neurolinguistic and and MRI study].

A 33 year-old woman developed an alexia without agraphia, a color anomia, a right hemianopia, an aphasic amnesia and a verbal amnesia. The brain MRI showed the lesions in the left splenium of corpus callosum, forceps major, optic radiations and anterieur temporal lobe. The fact that she measured writing comprehension and had complete recovery of reading impairment despite the persistence of anatomic lesions plead in favour of an active participation of the right hemisphere (RH) on reading; this capacity of the RH may be due to the linguistic particularities of arabic writing.

Adult↗

[Dermatomyositis and Wilson disease].

A 15 year-old girl developed both a dermatomyositis and a Wilson's disease. A clinical remission was obtained with steroids and D-penicillamine. The potential role of cupric intoxication in the pathogeny of the muscular syndrome is discussed.

Adolescent↗

Establishment of T-lymphoid cell lines from Morroccan patients with tropical spastic paraparesis.

Two T-cell lines were established from peripheral blood mononuclear cells of two Moroccan patients with tropical spastic paraparesis and then named PR52 and PR144. The two cell lines showed a T lineage of activated CD4+ with high density of Tac+ (IL2 receptor). No expression of CD8 was observed. The virus particles were detected by reverse transcriptase activity and the viral antigens were also detected by immunofluorescence (IF) and Western blot. After six months of culture greater than 90% of the cells exhibited HTLVI antigen by IF. Lysate virus particles on Western blot analysis revealed p19,p24, and p53 gag protein similar to those detected in C91/PL virus particles from an adult T-cell leukemia (ATL) patient. gp46 and gp61 were also weakly detected. These two T-cell lines established will serve as substrate for further comparative studies on TSP and ATL isolates.

Base Sequence↗

[Thrombosis of the upper longitudinal sinus and syphilitic cranial osteitis].

A 33-year old man developed progressive intracranial hypertension with papilloedema due to thrombosis of the superior sagittal sinus (SSS) by extension of a skull osteitis. Serological tests for syphilis were positive in blood, CSF and synovial fluid. Under treatment with penicillin and corticosteroids signs of intracranial hypertension and CT scan abnormalities disappeared. SSS thrombosis persisted at angiographic control.

Adult↗

[Amyotrophic lateral sclerosis syndrome of syphilitic origin. 5 cases].

We studied 5 cases of syphilitic lateral amyotrophic sclerosis. The diagnosis was based on the presence of a lymphocytic reaction in the CSF and positive VDRL and TPHA reactions in both blood and CSF. Clinically, the disease affected the arms in 3 cases and produced paraplegia in 2 cases. The gradual extension of amyotrophy over several months, the diffusion of electromyographic abnormalities and the finding of spinal cord atrophy at myelography and CT suggested a subacute ischemic mechanism with meningo-myelic arteritis involving the anterior horns. After treatment with penicillin G in high doses, the outcome was constantly favourable, with improvement of motor deficit in 4 cases and stabilisation in 1 case in a 5 to 13 years' follow-up.

Adult↗