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Biomedical subjects

T C Huang

Publications and source records attributed to T C Huang.

At least 55 records · Page 3Linked to original sources
PubMed1981

Effect of protozoa on bacterial degradation of an aromatic compound.

Prototrophic and growth factor-requiring strains of Alcaligenes spp. were used to study the effect of a protozoan, Tetrahymena pyriformis, on the degradation of p-aminobenzoate. The protozoan inhibited activity of the prototrophic bacterium by reducing its population size. For the growth factor-requiring strain of Alcaligenes, T. pyriformis provided the required growth factors so that the predator permitted the bacteria to grow and to continue p-aminobenzoate degradation. T. pyriformis inhibited bacterial activity when the amino acid supply was in excess, but activity of the auxotrophic strain of Alcaligenes was stimulated by the protozoan when the amino acid supply was limiting, although the bacterial population size was reduced by the protozoan.

Journal Article↗
PubMed1979

Distribution of egg deposits and gross lesions in nonhuman primates infected with Schistosoma haematobium (Iran).

Widespread tissue egg deposits and gross lesions were recorded in 15 species of primates subsequent to Schistosoma haematobium (Iran) infections of variable intensity and duration. Considerable extra-intestinal involvement as well as pathology in different parts of the urogenital system were observed. Transitional cell carcinoma of the urinary bladder was recorded for Cebus apella.

Animals↗
PubMed1979

Haematobium schistosomiasis in the squirrel monkey (Saimiri sciureus).

The squirrel monkey (Saimiri sciureus) accommodates Schistosoma haematobium moderately well. Adults occur in the major viscera but the extent of tissue egg deposits and associated pathology is variable. Pathologic involvement of the urogenital system occurs in a large proportion of hosts exposed to moderate to heavy infections, and bladder pathology is indicative of conditions associated with bladder carcinoma.

Animals↗
PubMed1978

Experimental infection with Schistosoma intercalatum (Fisher, 1934) in the chimpanzee (pan troglodytes) and the gibbon (Hylobates lar).

Two young chimpanzees (Pan troglodytes) and two adult gibbons (Hylobates lar), each exposed to 1,000 cercariae of Schistosoma intercalatum (Cameroon), were examined at 79 and 82 wk and 61 and 69 wk, respectively, post-infection. Based upon worn returns and tissue egg deposits, these primates can be employed as hosts for experimental schistosomiasis intercalata. However, no histopathology was detected in the urogenital system.

Animals↗
PubMed1977

Scanning electron microscopy of integumental surfaces of Schistosoma intercalatum.

Scanning electron microscopy was employed to study critical point dried Schistosoma intercalatum adults at 120 to 6,000 X magnifications. Well-developed integrumental elevations, or bosses, with variable spination account for the roughness of the male schistosome. The female is relatively smooth even though it possesses minute spines on the posterior part of the body. SEM reveals that the gynecophoral canal of the male, especially the presence of a gynecophoral fold, provides an effective means for clasping the female when in copula.

Animals↗
PubMed1976

Scanning electron microscopy of the integumental surfaces of Schistosoma haematobium.

The integumental surfaces of critical point dried S. haematobium were studied by scanning electron microscopy at 34 to 8,000 magnifications. There are marked differences between the surface structures of male and female as well as from one part of the same parasite to another. The surface of the male schistosome is moderately rough while that of the female is relatively smooth. SEM reveals certain basic features such as spines in the oral sucker and the acetabulum of both sexes which may facilitate rasping and/or attachment of the parasite for residence in the bloodstream of the definitive host. The lining of the gynecophoral canal is roughened by minute spines. The presence of a gynecophoral fold may enhance anchorage of the female in the grasp of the male. The significance of visualization of surface features by SEM as a means for differentiating species is not yet known.

Animals↗
PubMed1976

Proliferative epithelial lesions of the urinary bladder in cynomolgus monkeys (Macaca fascicularis) infected with Schistosoma intercalatum.

Five cynomolgus monkeys (Macaca fascicularis) were infected with Schistosoma intercalatum, a helminth that is morphologically similar to Schistosoma haematobium. Infections were readily established and remained active until the monkeys were sacrificed 21 to 84 weeks after exposure. Although the schistosomes were located predominantly in mesenteric and hepatic portal venules, schistosome eggs were found in the bladders of 3 monkeys. Nodules of atypical epithelial cells interpreted as superficially infiltrating undifferentiated bladder carcinomas were found in one monkey 23 weeks after infection. These sessile tumors differ strikingly from the well-differentiated, papillary transitional cell tumors previously reported from several species of experimental animals infected with S. haematobium. The tumors are also dissimilar to the squamous cell bladder tumors associated with S. haematobium infection in man but may nonetheless be useful for investigations of schistosomal bladder cancer.

Animals↗