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Biomedical subjects

T C Demos

Publications and source records attributed to T C Demos.

At least 73 records · Page 4Linked to original sources

Multimodality approach to pericardial imaging.

In this chapter, three modalities--computed tomography, nuclear magnetic resonance imaging, and echocardiography--have been discussed. Each of these techniques offers unique advantages in the diagnosis of pericardial disease. Although echocardiography is the least expensive, most sensitive, and least invasive technique for the identification of pericardial effusion, false-positive and negative studies may be encountered. These are often resolved with the use of computed tomography and may be resolved with magnetic resonance imaging. Plain film radiography still has the advantage of identifying pericardial calcifications and will suggest the diagnosis of large pleural effusions at low cost and radiation dose. Exquisite portrayal of cross section anatomy using CT will aid in the diagnosis of multiple small tumor deposits and will clearly identify pericardial thickening. The value of magnetic resonance imaging awaits carefully controlled blinded studies, but its role in characterization of the content of pericardial effusions appears especially promising.

Cardiomyopathy, Restrictive↗

Sinus histiocytosis with massive lymphadenopathy: skeletal involvement.

A 9-year-old girl with known sinus histiocytosis with massive lymphadenopathy (SHML) has been followed since infancy. At age six, she developed swelling and pain in several joints. Subsequently, bone lesions were identified by scintigraphy and radiographs. Biopsy of the bone showed typical features of SHML. Bone lesions in this disease are rare. The lesions in this patient were followed for 3 years and remained unchanged despite chemotherapy.

Bone and Bones↗

Normal excretory urography in patients with primary kidney neoplasms.

The records of 65 consecutive patients discharged from the hospital with a diagnosis of primary parenchymal neoplasm of the kidney were reviewed. Four of the 65 patients had neoplasms which were not detected by excretory urography. The 4 undetected lesions included 3 renal cell carcinomas and 1 oncocytoma. All of these lesions projected from the anterior or posterior surface of the kidney, and all 4 were clearly demonstrated by computed tomography. Normal findings on an excretory urogram do not completely exclude a neoplasm of the kidney. When there is strong clinical suspicion of a renal neoplasm, computed tomography should be the initial examination or should be done even if the urogram has shown normal findings.

Adenoma↗

Benign soft tissue chondromatous lesion of the hand.

Four patients with benign soft tissue chondromatous lesions of the hand have been operated on and were followed for 4 years. During this follow-up period, two patients have had recurrences that were excised, and a third patient with a recurrence is scheduled for operation.

Adult↗

Pulmonary cavitations in Mycobacterium kansasii: distinctions from M. tuberculosis.

The initial radiographs of 263 patients with pulmonary Mycobacterium kansasii infections were reviewed. Forty-nine untreated patients with active disease had unilateral lesions containing cavities less than 2 cm in diameter. The radiographs of these 49 patients were studied further and were found to have four distinct patterns: pattern 1, a circumscribed opacity containing a single cavity (39%); pattern 2, a circumscribed opacity with multiple lucencies (39%); pattern 3, multiple round or oval opacities containing lucencies (8%); and pattern 4, complex uncircumscribed opacity with lucencies (14%). Adjacent pleural thickening, "drainage area disease," and a "tail" sign were common. The initial radiographs of 27 untreated patients with solitary cavitary lesions less than 2 cm in diameter due to M. tuberculosis were studied for comparison. Only 22% had patterns 1-3 and generally showed more extensive adjacent parenchymal disease than cases with M. kansasii. A single circumscribed opacity containing one or more small cavities together with a "tail" sign, "drainage area disease," and little adjacent parenchymal disease is highly suggestive of M. kansasii infection. Since this infection usually requires more vigorous chemotherapy than tuberculosis, awareness of these findings has a practical implication.

Diagnosis, Differential↗

Evaluation of superior vena cava syndrome by axial CT and CT phlebography.

Transverse axial computed tomography (CT) has been combined with CT digital phlebography to study nine patients with superior vena cava syndrome. Six were due to malignancy, two were secondary to benign disease, and one was a paraneoplastic manifestation. This combined CT approach successfully identified the abnormal morphology of the superior vena cava, demonstrating external compression, encasement, or intraluminal thrombus in all patients and the collateral venous channels in eight. The efficacy and advantages of this technique are discussed. This technique is a rapid, informative, and cost-effective method for the workup of superior vena cava syndrome. The CT digital phlebogram, however, is not successful in regularly and optimally opacifying the normal superior vena cava because of the limited amount of contrast material, dilution effect of the nonopacified incoming flow from the jugular and azygos veins, and the lack of image enhancement from the CT digital scanograms.

Adenocarcinoma↗

The radiologic diagnosis of complications following gynecologic surgery: radiography, computed tomography, sonography, and scintigraphy.

673,000 hysterectomies were done in the United States in 1981. The mortality rate of 16.4/100,000 was less than that for appendectomy. Gynecologic surgery, however, is the most common surgical cause of complications related to the urinary tract with the reported incidence varying from less than 1 to 10%. We reviewed the charts of 1403 patients who had 736 abdominal, 315 vaginal and 143 radical or modified radical hysterectomies. Seventy (5%) patients had complications. Thirty-two (2.2%) patients had 35 complications related to the urinary tract. Complications directly related to surgery were grouped into ureteral injuries (13), fistulas (10), post surgical fluid collections (13), and hydronephrosis following radical hysterectomy. Characteristic images obtained by radiography, sonography (US), computed tomography (CT), and nuclear medicine (NM) are presented, and their use in each group of complications is summarized in the conclusion.

Ascites↗

Metastatic leiomyosarcoma of the kidney with spontaneous perirenal hemorrhage.

Spontaneous subcapsular or perirenal hemorrhage is most often associated with a primary renal neoplasm which may be malignant or benign. No case of metastasis to the kidney causing such hemorrhage has been reported. The patient presented here had spontaneous perirenal hemorrhage due to metastasis to the kidney from a leiomyosarcoma of the uterus.

Adult↗

Unicaliceal kidney associated with posterior urethral valves.

Unicaliceal kidneys are normal in several mammals, including monkeys. There have been 10 patients with this anomaly reported on in the literature and most have had additional anomalies of the urinary tract. We report on a man with a unicaliceal kidney who also had posterior urethral valves.

Adult↗

Chronic stridor in a child: CT diagnosis of pulmonary vascular sling.

A child without chronic stridor and tracheal narrowing was considered to have a primary tracheal abnormality. Computed tomography (CT) identified an aberrant left pulmonary artery originating from the right pulmonary as the cause of the tracheal abnormality. The advantages of CT over conventional studies are discussed.

Child↗

Multiple endocrine neoplasia (MEN) syndrome type IIB: gastrointestinal manifestations.

Multiple endocrine neoplasia syndrome IIB is an inherited autosomal dominant disorder with variable penetrance. Multiple organ systems are involved with a characteristic triad of medullary thyroid carcinoma, pheochromocytoma, and alimentary tract ganglioneuromas. Most patients have characteristic facies with patulous lips and thickened tarsal plates of the eyelids. The entire gastrointestinal tract can be involved from tongue to anus. Tongue nodules are common. Altered intestinal motility, dilation, diverticula, and mucosal abnormality may be seen radiographically. Gastrointestinal symptoms are common, may be the presenting manifestation of the syndrome early in life, and allow the radiologist to suggest the proper diagnosis. Five patients are described. All had megacolon.

Adult↗

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Humans↗