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Biomedical subjects

T Bruzzese

Publications and source records attributed to T Bruzzese.

At least 37 records · Page 2Linked to original sources
PubMed1976

A soluble mepartricin complex (SPA-S-222) of potential oral and parenteral utility in fungal and protozoal infections.

Acute toxicity and absorption data of a soluble complex of mepartricin with sodium laurylsulphate (SPA-S-222) active against C. albicans and T. vaginalis are reported. The results demonstrate an improved bioavailability with respect to the insoluble substance. Preliminary clinical trials proved the good tolerance of the substance and its effectiveness in oral treatment of vaginal trichomoniasis.

Administration, Oral↗
PubMed1975

Synthesis and biological properties of alkyl esters of polyene antibiotics.

Several new alkyl esters of polyene antibiotics were prepared by an improved general procedure, and their toxicity and microbiological activity were tested. Some of these alkyl esters were more active than the nonesterified polyenes against Candida albicans but were less effective than the known methyl esters. Their toxicity was much less than that of the parent compounds.

Animals↗