The relationship of home cage feeding behavior to acquisition of schedule-induced polydipsia in the rat.
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Biomedical subjects
Publications and source records attributed to T Brown.
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An in-training examination for family practice residents has been developed and used in a regional network residency program over the past three years. The most striking result has been the strong preference expressed by residents for question-specific feedback in order to facilitate learning after taking the examination. A well-designed in-training examination has the potential to meet both individual resident and program goals as an additional measure of resident performance and growth, as well as of the effectiveness of teaching in the various curricular areas. In-training examinations for residents are in use by 12 other specialties in medicine, and have been well-accepted by program directors and residents. A nationally-sponsored in-training examination for family practice residents is needed which includes maximal teaching capability through comprehensive and specific feedback.
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The clinical and laboratory features of a case of alphamethyldopa-induced thrombocytopenia are described. This is the second reported case in which the presence of alpha-methyldopa-induced platelet antibodies have been demonstrated.
The effects of reduced auditory feedback were investigated using an accurately calibrated binaudal pure tone producer on 27 stuttering children and 68 non-stuttering controls. A comparison was made of both auditory hearing and discomfort thresholds in the two groups; the hearing thresholds did not differ between the groups. The results did however replicate an earlier finding which suggested that stutters have a lower threshold for auditory discomfort than do normal speakers, and showed that fluency is inversely related to auditory feedback. The discussion suggests that a necessary cause of stuttering is a physiological abnormality in side-tone conduction and central processing.
The study of jaw movements or mandibular kinematics has important applications in many fields of clinical dentistry and provides a basis for modern concepts of dental occlusion. Movement patterns must be considered in conjunction with the mandibular articulation, the system of synovial joints, muscles and associated structures concerned with jaw suspension and jaw movements. Kinematics includes the study of articulating surfaces and the movements between them as well as the paths mapped out by a point on the moving bone. In this review, joint movements are considered from a theoretical approach based on the mechanics of articular surfaces, and by reference to recent experimental studies of condylar motion. Movements of the mandible are related to the envelope of motion traced out by the central incisor point. Attention is also given to border paths, reference positions and masticatory movements of the jaw.
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A modified nitroblue tetrazolium test (NBT) is described which is suitable for routine application in the haematology or bacteriology laboratory and which provides a rapid aid to the diagnosis of bacterial infection. Hitherto published methods have recommended the use of heparinized whole blood samples for the performance of the NBT test. However, we have demonstrated that the use of the sucrose polymer Ficoll permits the test to be carried out on buffy coats prepared from venous blood anticoagulated in sequestrene (EDTA). The mean percentage of NBT-positive neutrophils in 60 healthy control subjects was 6.1. The mean percentage of NBT-positive neutrophils in 56 patients with confirmed or presumed bacterial infection was 34.2. Scores within the normal range were observed in 13 patients in this group. Forty-eight individuals with viral infection yielded a mean percentage of NBT-positive neutrophils of 8.5. Six patients in this group gave scores above the upper limit of normal. Both pathological groups are described in detail and applications of this test are suggested.
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