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Biomedical subjects

T Blum

Publications and source records attributed to T Blum.

31 records · Page 2Linked to original sources

Recording neuromagnetic fields in retinitis pigmentosa.

After stimulation of the left and right half-fields, it is possible to record contralateral visually evoked neuromagnetic fields (VEF) without any reference to the size of the half-field stimulus display. The test reacts extremely sensitively upon each shifting of the half field into the periphery to the left or right. By application of half-field pattern stimuli of an extremely high or low spatial frequency, characteristic deviation angles are obtained for both the spatial frequencies after evaluation of the VEF amplitudes. By this method the foveal acuity in RP can be investigated with an objective procedure to a very high degree of accuracy.

Fovea Centralis↗

First magnetoencephalographic recordings of the brain activity of a human fetus.

Using a one-channel neuromagnetometer adjusted to a special site on the mother's abdomen, we succeeded in recording prenatally, for the for the time, human fetal brain activity in late pregnancy. It was possible to record both the fetal auditory-evoked neuromagnetic field and to detect fetal brain activity by analysis of the frequency spectrum. Such measurements may soon prove valuable for the noninvasive investigation of human brain function.

Audiometry, Evoked Response↗

[Registration of visual evoked neuromagnetic fields following partial field stimulation of the fovea].

Visual evoked neuromagnetic fields were recorded after stimulation of the right and left foveal half-field and of the right lower and upper quadrant. A contralateral topography of the dominant complex of the visual evoked field was measured on the skull after right and left half-field stimulation. After switching from the right half-field stimulation to the stimulation of the right quadrants we observed large individual differences in our subject group. A possible morphological explanation is that the more elementary stimulation in the quadrants is connected with a greater number of dipole orientations as compared with the less elementary stimulation in the half-fields.

Adult↗

[Fetal magnetoencephalography I: 1st prenatal registration of auditory evoked neuromagnetic fields].

Using a SQUID gradiometer of the second order, we succeeded in recording a prenatal auditory evoked neuromagnetic field in the 35th week of pregnancy. After sonographic localization of a suitable recording site on the fetal skull, the neuromagnetic field was recorded above the mother's abdomen. It will be necessary to develop special gradiometer configurations for further prenatal registrations of the stimulus-related and spontaneous fetal brain activity.

Electroencephalography↗

Tu-M2-PK in the blood of testicular and cubital veins in men with testicular cancer.

We wanted to verity whether M2-PK is a useful marker in testicular cancer. In a prospective study of 20 consecutive patients, blood was drawn from the testicular and the cubital vein before semicastration and later. For the detection of M2-PK we used the Assay of ScheboTech. In the testicular vein M2-PK was 11.2 U/ml. In the cubital vein it was 6.2 U/ml before semicastration, increasing in the following days. There were no significant differences between testicular and cubital vein blood, between the non-metastasized patients and the metastasized stages and between the patients with seminoma and non-seminomatous tumors. There is no profit in the diagnosis of testicular cancer using Tu-M2-PK.

Biomarkers, Tumor↗