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Biomedical subjects

T Barrie

Publications and source records attributed to T Barrie.

29 records · Page 2Linked to original sources

The visual status of diabetics on renal replacement therapy (RRT).

The visual status of 48 patients with end-stage diabetic nephropathy who were undergoing treatment either by dialysis or transplantation was assessed. At the time of starting dialysis, the vision was good in 27 (56 per cent), impaired in 7 (15 per cent) and of navigating standard only in 12 (25 per cent) while the remaining 2 (4 per cent) had no useful vision. During the time on dialysis and/or following transplantation, vision improved in 6 patients (12 per cent), deteriorated in 9 (19 per cent) and remained unchanged in 33 (69 per cent). Changes in the degree of retinopathy in the 96 eyes resulting either from treatment of the renal failure or laser therapy were noted. The reasons for any changes in vision and the effect of ophthalmic treatment will be discussed.

Adult↗

Colour vision of diabetics.

The Farnsworth-Munsell 100-hue test has been assessed as a screening test for the detection of diabetic retinopathy likely to benefit from laser photocoagulation therapy. Two hundred and thirty-two diabetic eyes of 126 patients were tested. The results were assessed both for total error score relative to age and for the presence of polarity. Although the incidence of abnormal colour discrimination was found to correlate with the severity of retinopathy, the test was not sufficiently selective to be of value as a screening test in the detection of retinopathy requiring treatment.

Aged↗

Candidal endophthalmitis in Glaswegian heroin addicts: report of an epidemic.

Nine heroin addicts with presumed candidal endophthalmitis were seen in Glasgow between November 1982 and April 1984. Six patients during a two month period in 1983. The physical symptoms and signs observed, results of laboratory investigations and responses to anti-fungal chemotherapy are reported. Epidemiological factors relating to possible sources of infection are explored.

Adolescent↗

The prevalence of carotid artery disease in patients presenting with amaurosis fugax.

Ninety-five patients with amaurosis fugax were investigated for extracranial carotid artery disease. A doppler system combining imaging with spectrum analysis was used. Stenosis (greater than 25 per cent) and occlusion of the ipsilateral extracranial internal carotid artery occurred in 30 per cent and 26 per cent of patients respectively. The association of amaurosis fugax with ipsilateral carotid disease is highly significant. The role of this Doppler technique in the investigation of patients with amaurosis fugax is considered.

Adult↗

SLE retinopathy: evaluation by fluorescein angiography.

Fifty-two patients with systemic lupus erythematosus (SLE) were examined by fluorescein angiography, and retinopathy was detected in 15. Three patterns of retinopathy were discerned: 4 patients had disc vasculitis, 6 had multiple cotton-wool spots, and 5 had a normal fundal appearance but fluorescein leakage on angiography. One patient had arterial occlusive disease with retinal neovascularisation and another had extensive venous disease. With 3 exceptions retinopathy was found only in patients with active SLE. No association was discovered between retinopathy and cerebral disease; in particular, fluorescein angiography did no assist the diagnosis of mild cerebral lupus.

Adult↗

Serious retinopathy in a diabetic clinic: prevalence and therapeutic implications.

In a series of 1000 patients examined consecutively in a large diabetic clinic, 95 (9.5%) were classified as having serious diabetic retinopathy. The definition was confined to exudative retinopathy (macular oedema or hard exudates encroaching upon the macula), proliferative retinopathy, and retinal ischaemia (as evidenced by the presence of soft exudates in the absence of hypertension, together with characteristic vascular changes). The diagnosis of serious diabetic retinopathy is always accompanied by a need for specialised ophthalmological assessment (including fluorescein angiography) and, often, urgent photocoagulation. Investigation and treatment are time-consuming, and such patients therefore constitute a major workload for the ophthalmological services: the average time for an ophthalmic consultation was found to be 20 min, and when fluorescein angiography was added to this the time increased to 40 min. The average time spent on photocoagulation for neovascularization was 2 h for each eye, and for exudative retinopathy 30 min for each eye.

Adult↗

Snap-shot decisions.

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Diabetic Retinopathy↗