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Biomedical subjects

T Banerjee

Publications and source records attributed to T Banerjee.

At least 19 recordsLinked to original sources
PubMed1991

Effect of 'Pan Masala' on the germ cells of male mice.

Cytogenetic analyses of meiotic metaphase I germ cells and abnormalities of head morphology of caudal sperms were conducted in male mice following oral feeding of Pan Masala. The substance was ground to a fine powder, dispersed in polysorbate solution and administered via gavage to the animals at 84, 420 and 840 mg/kg body weight at the rate of 10 ml/kg body weight. Polysorbate and cyclophosphamide served as the vehicle control and positive control respectively. The two higher doses, 420 and 840 mg, gave a significant increase in the frequency of X-Y univalents and breaks over those of the vehicle control. Frequency of sperm head abnormalities were significantly high for all the doses tested. The results indicate that Pan Masala is a potent clastogen, reaches the testes and affects the germinal cells.

Administration, Oral↗
PubMed1991

Structure of 4-(3-chlorophenyl)thiosemicarbazide.

C7H8ClN3S, Mr = 201.67, monoclinic, P21/c, a = 6.914 (5), b = 4.304 (4), c = 30.306 (3) A, beta = 94.66 (3) degrees, V = 899.0 (1) A3, Z = 4, Dm = 1.54, Dx = 1.490 Mg m-3, lambda (Cu K alpha) = 1.5418 A, mu = 5.54 mm-1, F(000) = 416, T = 298 K, final R = 0.048 for 1219 observed reflections. The S and terminal hydrazinic N atoms are in a trans conformation. As a result of the sigma-electron-withdrawing effect of the Cl atom at the meta position in the phenyl ring with respect to the thiosemicarbazide chain, the net negative charge on the terminal N atom decreases compared to the p-chloro and p-methoxy derivatives. The antibacterial activity of the compound is also lowered.

Chemical Phenomena↗
PubMed1988

Structure of salicylaldehyde thiosemicarbazone.

C8H9N3OS, monoclinic, C2/c, a = 14.206 (3), b = 14.244 (4), c = 10.457 (4) A, beta = 116.18(2) degrees, V = 1898.9 (8) A3, Z = 8, Dm = 1.387, D chi = 1.366 g cm-3, lambda(Mo K alpha) = 0.71069 A, mu = 2.90 cm-1, F(000) = 816.0, T = 298 K, final R = 0.0429 for 1322 observed reflections. The S and hydrazinic N atoms lie trans. The lowering of antibacterial activity compared to that of 4-phenylthiosemicarbazide may be correlated with the decrease in negative charge on the hydrazinic N atom. The crystal structure is stabilized by hydrogen bonding, stacking interactions and van der Waals forces.

Aldehydes↗
PubMed1977

Nonhealing myelomeningecele in an adult.

A case of myelomeningocele in a 20-year-old woman is presented. The partially healed scar continued to produce infected debris despite vigorous local therapy. She died because of eventual local and retroperitoneal invasion of squamous cell carcinoma. The possible benefits of decisive planning are discussed.

Adult↗
PubMed1977

Intracranial epidermoid tumor: discussion of four cases.

Four cases of intracranial epidermoid tumor are presented. These are uncommon tumors with no specific signs or symptoms, and their diagnosis depends upon a high index of suspicion. Computerized axial tomography (CAT scan) was helpful in diagnosing one of the cases described and undoubtedly will be instrumental in identifying future cases. Epidermoid tumors are biologically benign. They are often amenable to resection, and therefore tissue diagnosis before starting any therapy is important.

Adult↗
PubMed1977

Review of 18 years' experience with pituitary tumors.

The presenting signs, symptoms, roentgenographic findings, endocrine evaluations, treatment, and results in 68 cases of presumed pituitary adenomas treated over an 18-year period are discussed. The most common symptoms were headache, acromegalic changes, visual symptoms, and amenorrhea. Most common physical findings were obesity, acromegaly, and visual field defects, usually bitemporal hemianopsia. Roentgenographic evidence of sellar erosion was almost universal but angiography and pneumoencephalography were required to evaluate suprasellar extension. Brain scan was not considered a particularly useful diagnostic tool. Endocrine status was best evaluated by a battery of tests including 17-OH, 17-KS, T3, T4, PBI, ACTH stimulation, and FSH and STH levels. (Prolactin levels are currently being obtained, also). Surgical specimens were obtained in 29 patients, with subsequent diagnoses of 22 chromophobe adenomas, five eosinophilie adenomas, one cystic adenoma, and one necrotic tumor. All five eosinophilic tumors came from acromegalic patients. Patients treated by operation alone or operation followed by radiotherapy generally had less "medical morbidity" than did patients who received radiotherapy alone.

17-Hydroxycorticosteroids↗
PubMed1977

Abnormal movements with hydrocephalus. Case report.

The author reports the case of a pituitary dwarf with choreoathetoid movement of the tongue and both arms as results of a shunt malfunction. He had undergone craniotomy for excision of a suprasellar craniopharyngioma, and 13 years later complete cerebral angiography and Conray ventriculography showed massive hydrocephalus with no evidence of tumor recurrence. Revision of the shunt was followed by complete recovery of the movement disorder.

Adult↗
PubMed1976

Carpal tunnel syndrome: discussion of operating technics.

A case of carpal tunnel syndrome's is presented. Histologic examination of the volar carpal ligament showed fibrocartilaginous changes suggesting a progressive degenerative phenomenon. Operative intervention relieved the pain and disability. It is implied that biopsy of the carpal ligament and/or the synovial sheath often will be helpful in making a complete diagnosis. The results of this simple operating technic are contrasted with other procedures.

Carpal Tunnel Syndrome↗
PubMed1976

Sciatic entrapment neuropathy. Case report.

A case of sciatic entrapment neuropathy is discussed. When evaluating patients with unilateral leg pain and paresthesias, one should consider the possibility of entrapment of peripheral nerve. Electrodiagnostic studies are helpful in establishing the diagnosis.

Adult↗
PubMed1976

Oblique muscle splitting incision for cervical laminotomy.

A muscle-splitting incision for cervical disc disease is described. It is based upon sound surgical principles. There have been no wound complications in the last 60 patients treated by the authors. Its most stringent demand is that the surgeon be familiar with the anatomical planes to be certain of the level which he wishes to explore.

Cervical Vertebrae↗
PubMed1976

Chromophobe adenoma and chiasmal syndrome without enlargement of the bony sella.

Four cases of chiasmal syndrome resulting from chromophobe adenoma with normal-sized sella turcica are reported. The predominantly suprasellar growth of these tumors was probably the result of a well-pneumatized sphenoid sinus and/or a congenitally deficient diaphragma sellae. In patients with chiasmal syndrome, a high suspicion of a surgically treatable lesion must be maintained in spite of radiographs showing a normal-sized sella. In spite of the difficulties presented by normal variations, subtle findings should be searched for on the plain films and given additional weight in the patient with a chiasmal syndrome. An aggressive diagnostic work-up, including pneumoencephalography with thin-section tomography, should be pursued in all such patients before accepting some alternate explanation, such as demyelinating disease, for visual impairment.

Adenoma, Chromophobe↗