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Biomedical subjects

T Bacia

Publications and source records attributed to T Bacia.

At least 19 recordsLinked to original sources
PubMed2000

[Surgical outcome of temporal lobe epilepsy].

Results of the surgical treatment of temporal lobe epilepsy--Authors present their own experience in the surgical treatment of temporal lobe epilepsy. 403 patients were operated upon. The age of the patients was not limited. The beginning of the epilepsy was in most cases in early childhood, however the conservative treatment was continued for a very long time, usually over 10 years. The modern diagnostic tools, especially MRI, make it possible to diagnose the temporal epileptic focus more often, than previously, especially in cases with morphological substrate. Temporal lobectomy with amygdalo-hippocampectomy was performed. The follow-up was at least 3 years after surgery. Outs of 343 patients examined in this period 175 were cured, without seizures after surgery. Next 61 patients had no more than 2 small attacks a year. So in 69% of patients the result was very good or satisfactory. The neuropsychological investigation revealed that in most patients the IQ improved. Their quality of life improved markedly according to their own opinion.

Adult↗
PubMed1998

[The comparison of ketamine with methohexital and thiopental in the intraoperative EEG in drug-resistant epilepsy].

UNLABELLED: The acute (ECoG) was examined in 291 patients with intractable epilepsy, without structural brain lesion--from 1971 to 1997. Temporal lobectomy was performed in 198 cases and extratemporal (frontal, parietal or occipital) in remaining 93 cases to achieve seizure control. Epileptic foci was activated during acute ECoG by i.v. administration of ketamine (154 cases) or short-acting barbiturates--methohexital (110 cases) and thiopental (27 cases). RESULTS: Ketamine significantly more often caused ECoG identified electrographic seizures than methohexital: p = 0, 00001 or thiopental, which in no cases resulted in seizures. Also electrographic seizures occurred more frequently after administration of ketamine in patients with the extratemporal seizure focus localisation in comparison with temporal focus (p < 0.05). Electrographic seizures provoked after administration of ketamine improved the localisation of the area to be resected, more often in extratemporal epileptic foci. CONCLUSIONS: The results of our investigations indicate that ketamine more effectively activated epileptic focus than short-acting barbiturates.

Adolescent↗
PubMed1994

Problems with electrical signs of epileptic focal discharges recorded from the scalp.

From 1957-92, 3235 patients with chronic drug-resistant epilepsy were admitted and examined as candidates for surgery, in 639 classical resective intervention, removal of epileptic foci, was performed. In 101 patients other functional or disconnection surgery was performed. Based on this experience some problems and difficulties of bioelectrical investigation and localization of epileptic foci by scalp EEG recording are presented.

Adolescent↗
PubMed1992

The results of the surgical treatment of occipital lobe epilepsy.

Out of 502 patients with surgically treated drug-resistant chronic epilepsy (tumour cases excluded) in 12 (2%) a clear occipital focus was found. The pattern of seizures was in most cases nonspecific and polymorphic. EEG examination and neuroradiological findings led to proper localization of the epileptogenic focus. Partial or total occipital lobectomy was performed. Follow-up from 4 to 20 years revealed a satisfactory result in 11 of the surgical cases. One patient was lost to follow-up. Brain scarring was found in the histological examination of specimens in 9 out of 12 patients. The results of the surgical treatment of occipital lobe epilepsy are much better than in other localizations of epileptogenic foci.

Adolescent↗