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Biomedical subjects

T B Hunter

Publications and source records attributed to T B Hunter.

At least 55 records · Page 3Linked to original sources

Role of surgical treatment in the management of complications of the gastrointestinal tract in patients with leukemia.

The clinical course of patients with leukemia, specifically after treatment, is complicated by opportunistic infections, often derived from the gastrointestinal tract. Four hundred and thirty-eight patients with leukemia were treated at the Arizona Health Sciences Center from 1976 to 1985. Fifty-five (13 per cent) had 60 major gastrointestinal complications develop. Thirty-seven were treated medically with a mortality rate of 51 per cent, while 18 who were treated surgically had a 17 per cent mortality rate. These infections usually occur during induction or consolidation chemotherapy. Positive blood cultures and white blood cell counts of less than 2,500 per millimeter are a frequent occurrence. The most common complications of the gastrointestinal tract are enterocolitis, perirectal sepsis and bleeding. Because of the combined defects in phagocytosis (neutropenia), antibody production and cell mediated immunity, opportunistic infections (such as viral, fungal, parasitic or bacterial) are frequent and often lethal, despite routine antibiotic coverage. A protocol to identify a subset of patients with septic leukemia who may require emergency surgical treatment is vital since death in this group is most commonly from undiagnosed sepsis or progression of hematologic defects. This protocol should include repeated physical examinations, daily roentgenograms of the abdomen, liberal use of endoscopy, contrast roentgenography and computed tomography (CT) or ultrasound. Extensive surgical procedures can be safely carried out in patients with leukemia. The diagnosis of leukemia should not be a deterrent to emergency surgical exploration.

Adolescent↗

Personal computer needs for the radiologist.

This article reviews the computer system hardware and software, applications programs, and computer network services that are available on microcomputers for use by the radiologist. The American College of Radiology Institute computer network is described, which is specifically designed to help the practicing radiologist.

Computers↗

Radiologic total lung capacity measurement. Development and evaluation of a computer-based system.

The development of a computer-based radiologic total lung capacity (TLC) measurement system designed to be used by non-physician personnel is detailed. Four operators tested the reliability and validity of the system by measuring inspiratory PA and lateral pediatric chest radiographs with a Graf spark pen interfaced to a DEC VAX 11/780 computer. First results suggest that the ultimate goal of developing an accurate and easy to use TLC measurement system for non-physician personnel is attainable.

Adult↗

Angiosarcoma of the breast. Two case reports and a review of the literature.

Two cases of angiosarcoma of the breast are presented. They are of particular interest in that one patient is a long-term survivor, the 19th reported to date, and the other presented with contralateral breast involvement without evidence of disseminated disease. The world literature is reviewed and a discussion is presented of the clinical features, treatment, histopathologic features, and prognosis of this rare breast neoplasm. Tumor size and degree of tumor differentiation are the most important prognostic indicators, and in general a simple mastectomy is the treatment of choice. The value of adjuvant irradiation and chemotherapy is uncertain.

Adult↗

Barium capsules.

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Adult↗

Relation between pelvic phleboliths and diverticular disease of the colon.

The frequent occurrence of colon diverticula and pelvic phleboliths in older persons in Western society has been attributed to the long-term effects of a low-fiber diet. If diet is a common factor for both processes, their incidence should be related. A statistical study was performed to correlate the number and size of pelvic phleboliths with the amount of colon diverticular disease present at barium enema. Examination of barium enemas of 203 patients (98 male, 105 female) aged 60-69 years showed no statistical difference between the genders in regard to the location and amount of either diverticular disease or number and size of pelvic phleboliths . There was no statistical correlation between the amount of diverticular disease and the mere presence or absence of pelvic phleboliths . However, when phleboliths were present, there was a definite statistical correlation between the number and size of the phleboliths and the degree of diverticular disease present. On the basis of this study, the relation between phleboliths and colon diverticula seems complex and needs further examination.

Aged↗