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Biomedical subjects

T B Ducker

Publications and source records attributed to T B Ducker.

At least 109 records · Page 6Linked to original sources
PubMed1976

Fulminating parapontine epidermoid carcinoma in a four-year-old boy.

An unique case of primary intracranial epidermoid carcinoma in a 4-year-old boy is described. Its parapontine localization and malignant features combined to produce a fulminating clinical course simulating an intra-axial mass lesion. The probable origin of the carcinoma from a benign epidermoid cyst is discussed. A review of the world's literature establishes not only the rarity of cyst-derived intracranial epidermoid carcinoma, but also its unprecedented occurrence in a child.

Aged↗
PubMed1976

Myelotomy for control of mass spasms in paraplegia.

A new myelotomy knife is described and a procedure, designed to sever certain reflex connections while preserving as many corticospinal connections as possible, is presented. Through intermittent dorsal midline incisions the gray matter lateral to the central canal is severed bilaterally under the microscope from L-1 to S-1. This procedure relieved mass spasms and hyperactive reflexes in 14 paraplegic or tetraplegic patients, but preserved postural reflexes and whatever voluntary motor power the patients had prior to myelotomy. Before myelotomy all patients were bedridden. Afterward nine patients were able to use a wheel chair and five were able to walk with the use of parallel bars or crutches.

Adult↗
PubMed1975

A method of quantitating injury inflicted in acute spinal cord studies.

Spinal cord trauma was induced in cats and Rhesus monkeys using an improved method which allows for accurate quantitation of the force delivered. The materials and methods described consist of a weight which is dropped down a centre shaft on to a strain gauge arch assembly which transfers the force to a teflon impounder resting on the exposed dura of the cord. The force transferred from the weight to the impounder is recorded by the strain gauge and thr force curve can be displayed on a storage oscilloscope. The force delivered to the cord can thus be photographed and quantitated. The construction of the strain gauge assembly and the application of the apparatus are discussed.

Animals↗
PubMed1975

Dynamic changes of cerebrospinal fluid in upright and recumbent shunted experimental animals.

The effect of positional change on intracranial CSF pressure, valve flow rates and atrial pressures were studied in 40 experimental dogs. The flow rate with a 30 to 60 mm H2O Holter valve changed from the recumbent to the head-up position: during the first minute it increased 2 1/2 times and then progressively decreased to become stabilized 20-30 min later at a value slightly lower than the head-up value. At the same time pressure dropped rapidly to -23 mm H2O and then slowly, during 30 min to -120 mm H2O. In dogs without a shunt the pressure drop was initially similar to that of shunted dogs but recovered to almost the initial positive pressure in 30 min. The flow rate from a reservoir to the atrium through a shunt system when changing to the head-up position showed a siphon effect. Atrial pressure does not change with positioning. The findings were similar with cisternal-peritoneal shunts. Flow rate, therefore, increase in the head-up position. Negative intracranial CSF pressure was due to a siphon effect through the shunt system.

Animals↗
PubMed1975

Adverse reactions to intrathecal saline injection for control of pain.

The authors report the results of a questionnaire regarding the use of hypertonic saline for the control of pain. Of 2105 patients so treated, nearly 11% had an adverse temporary symptom or sign, reported as an untoward reaction; slightly over 1% suffered a significant morbidity, of which paraplegia or quadriplegia was by far the most common, and two patients died (0.1%).

Humans↗