Proceedings: 99. Contribution of the main vascular components to the viscoelasticity of peripheral arterial walls.
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Animals↗
Biomedical subjects
T Azuma
Publications and source records attributed to T Azuma.
Interim results of a multicenter open study with auranofin in Japan.
We report the results of 47 of 116 rheumatoid patients, who took auranofin (AF) for more than 6 months. After 8-12 weeks of treatment with AF 3 mg bid, a remarkable improvement was observed especially in numbers of tender and swollen joints and duration of morning stiffness. The mean activity index before AF was 70.1% and the index decreased linearly for 6 months to 53.5%. AF was particularly effective in patients with high rheumatoid activity, as well as in those of short duration of disease and Stages I and II. Radiographic examination showed a possible prevention by AF of progression of bone destruction in the joints. A total of 86 side effects were reported in 50 cases: 36 gastrointestinal; 34 mucocutaneous and 16 others. Most side effects cleared during the treatment and no serious side effects were reported. Drug administration was discontinued in only 11 cases (9.5%). Blood gold level reached a plateau after 9 weeks (mean level was 0.67 micrograms/ml). Urinary excretion rate was parallel with the blood gold level.
Adolescent↗
[Rest angina induced by coronary artery spasm at the first septal artery: a case report].
A 41-year-old man was admitted because of chest pain at rest. The exercise test and coronary angiography were performed after all antianginal medication was discontinued for 24 hours. During the graded treadmill exercise stress test using the Bruce protocol, the patient had anginal pain with the electrocardiogram (ECG) showing ST segment elevation in leads V1 and V2. A baseline coronary angiogram disclosed 50% stenosis of the first septal branch of the left coronary artery. After a bolus of 0.1 mg ergonovine was administered into the coronary artery, the patient complained of typical anginal pain. Complete occlusion of the first septal branch was demonstrated, associated with significant ST segment elevation in leads V1-V3, right bundle branch block, and electrical axis deviation to the left on the ECG. The coronary occlusion reversed soon after nitroglycerin administration into the coronary artery. We diagnosed a rare case of angina pectoris caused by spasm of the minor branch of coronary artery, and that serial ECG changes might demonstrate ventricular septal ischemia including the cardiac conduction system. ST segment elevation in leads V1-V3 indicated ischemia of the ventricular septum, and right bundle branch block, axis deviation to the left, and increased amplitude of the precordial R wave might be induced by ischemia of the right bundle branch, left anterior bundle branch and septal branch in the cardiac conduction system supplied by the septal branches of the left anterior descending coronary artery.
Adult↗
Leiomyosarcoma occurring in the ligamentum teres of the liver: a case report and a review of seven reported cases.
We treated a 49-year-old male with leiomyosarcoma of the ligamentum teres of the liver. Preoperative hepatic imagings revealed a mass in the median segment of the liver. The patient underwent surgery, and the mass, measuring 6x5cm in size, was pathologically diagnosed as leiomyosarcoma arising from the ligamentum teres. To our knowledge, only eight cases of this rare tumor have been reported to date in the English literature.
Carcinoma, Hepatocellular↗
Bisubsegmental liver resection for gallbladder cancer.
BACKGROUNDS/AIMS: The ultimate goal was to determine the therapeutic value and indications of resection of segment IV inferior and segment V in patients with advanced gallbladder cancer. METHODOLOGY: Indications for systematic resection of the liver, particularly segment IV inferior and segment V as defined by Couinaud (1) or Healey (2), in patients with advanced gallbladder cancer, were examined in a total of 201 patients with advanced gallbladder cancer who underwent surgical resection were studied. RESULTS: All primary tumors invaded the subserosa of the gallbladder wall or deeper. Liver invasion and liver metastasis were studied clinicopathologically, and the long-term outcome was analyzed according to the procedure used for liver resection. CONCLUSION: The clinicopathological result suggests that resection of segment IV inferior and segment V of the liver may be beneficial in patients with liver bed type invasion less than 20 mm in depth.
Gallbladder Neoplasms↗