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Biomedical subjects

T Azuma

Publications and source records attributed to T Azuma.

At least 505 records · Page 28Linked to original sources

Neurosecretory cell: capable of conducting impulse in rats.

Electriic vtinulation of the rat neurohypophlysis in Situ evoked the unit action potentials. in the supraoptic nucleus. Compound and unit action potentials. were recorded from the isolated neurohypophysis stimulation. The applicaition of solutions high in potassium or devoid of sodium made the neurohypophysis inexcitable. Mammalian neurosecretsecretory cells have the neuronal properties generation and conduction of action potentials.

Animals↗

Clinical evaluation of D-penicillamine by multicentric double-blind comparative study in chronic rheumatoid arthritis.

In order to evaluate clinical efficacy of D-penicillamine (DP) a double-blind study was conducted by the Metalcaptase Research Group consisting of forty-one rheumatological centers in Japan. A total of 179 patients with rheumatoid arthritis (RA) was divided into two groups; one treated with 5 mg (control group) and the other with 100 mg (drug group) of DP in capsule form. The trial lasted 24 weeks. Global judgment by physicians revealed that improvement was found in 27% in the controls and 65% in the drug group. Adverse reactions occurred in 34% of the controls and 49% of the drug group. Skin rashes, taste disturbances, gastrointestinal upset and proteinuria were frequent in the drug group, but severe or fatal reactions could not be seen in this trial.

Administration, Oral↗