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T Amagasa

Publications and source records attributed to T Amagasa.

102 records · Page 6Linked to original sources

Surface roughness of squamous cell carcinoma of the oral mucosa.

The surface roughness value of 39 oral squamous cell carcinomas was measured by the Rmax method. The means of the eight measurement values of each carcinoma ranged from 87 micron to 1176 micron. The average value of all 39 lesions was 341 micron. The average value of the lesions of the papillomatous and granulomatous types was larger than that of the leukoplakic and erosive types. The lesions with the size of more than 2 cm in diameter were rougher than those of less than 2 cm. The lesions of the gingiva were rougher than those on the tongue. There was an inclination that the surface of the verrucous carcinoma was rougher than that of the invasive squamous cell carcinoma and that the surface of early carcinoma was smoother than that of the invasive squamous cell carcinoma.

Adult↗

Expression of bone morphogenetic protein genes in the human dental pulp cells.

Dental pulp has a potential to induce ectopic bone formation, but little is known about its mechanism. We thought that bone morphogenetic proteins (BMPs), members of the transforming growth factor-beta (TGF-beta) superfamily, are involved in the osteoinductive activity of dental pulp. In order to prove this assumption, we constructed a cDNA library from primary culture cells of human dental pulp (HDP cells), and screened the library with previously cloned cDNAs for mouse BMP-2 and -6 as probes. Three distinct cDNA clones encoding human BMP-2, -4 and -6 were isolated. By Northern blot analysis, specific transcripts of the genes of those BMPs were detected in the HDP cells. It was concluded that the BMPs were expressed in a certain population of dental pulp cells and might play some roles in ectopic bone formation by dental pulp.

Adolescent↗