Hodgkin's disease in Iraq: a clinico-pathologic study of 85 cases.
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Biomedical subjects
Publications and source records attributed to T Al-Saleem.
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The clinical and pathological features of 18 new patients with alpha heavy chain disease seen at two referral centres in Baghdad, Iraq, are described. The series included 14 males and four females ranging in age from 14 to 47 years. Almost all patients presented because of long-standing abdominal pain and diarrhoea. The tissue diagnosis and extent of the disease were established at laparotomy in most patients. Peroral jejunal biospy was used in a number of patients, mainly for follow-up. The serological abnormality was confirmed by immunoselection technique. Most of the patients had extensive thickening of the bowel wall and/or tumour masses of the small intestine and mesenteric nodes. Histopathological sections showed muscularis. Preliminary results of the treatment, including two long remissions, are reported. In general, our observations agree with those made by other authors, mostly from the Middle East and Africa. We believe that a high index of clinical suspicion, routine use of the immunoselection, and recognition of the early pathological changes may hopefully lead to the detection of more cases before the frank neoplastic phase of the disease.
Eight patients with skin lesions attributed to methylmercury exposure are reported. The outbreak of poisoning occurred in Iraq as a result of the handling and ingestion of treated grain and home-made bread. The skin manifestations were rather rare and varied in severity and histological appearance.
The case is reported of a 10-year-old boy who had severe diarrhoea with blood and muscus for 1 year which was found to be due to bilharzial polyposis of the rectum and sigmoid colon. He was treated first with antibilharzial drugs. Later, because of multiple polyps and secondary infection, local surgical resection was performed.
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Fifty cases of histologically proven intestinal tuberculosis are presented. Although intestinal tuberculosis is declining in Iraq, it is still a common condition affecting the bowel. Most of the lesions were primary and usually of bovine origin. The peak age incidence was between 30-39 years. Sexes were equally affected. The clinical presentation is usually intestinal obstruction, less commonly abdominal malignancy, malabsorption, or appendicular mass. All patients were explored and resection was carried out in 40; all were given antituberculous chemotherapy. The results are very satisfactory in the 47 patients that continued chemotherapy for over one year.