Morphological classification of liver cirrhosis based upon measurement of per cent of interstitial tissue in liver biopsy specimens.
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Biopsy↗
Biomedical subjects
T Aikawa
Publications and source records attributed to T Aikawa.
[Morphologic classification of hepatic cirrhosis, based on the percentage of the interstitial substances by biopsy].
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Biopsy↗
Temporal bone findings in central nervous system leukemia.
Central nervous system (CNS) leukemia is a pathologic condition whereby leukemic cells enter the cerebrospinal fluid (CSF) causing meningeal irritation syndrome. Temporal bone findings in the case of a 32-year-old man who died of CNS leukemia are presented. He complained of fullness of the ear 4 months prior to death and of dizziness 1 month prior to death. Leukemic cells were seen to have infiltrated the scala tympani of the basal turn in the cochlea, the saccule, and posterior semicircular canal along the vestibulocochlear nerve.
Adult↗
Tracheobronchial mucociliary clearance and alveolar epithelial permeability measured by PET with 18FDG powder.
Tracheobronchial mucociliary clearance and alveolar permeability were measured with positron emission tomography using a water-soluble dry aerosol, sodium-N-acetyl-neuraminate tagged with 2-deoxy-2-[18F]fluoro-D-glucose (18FDG powder). Five normal volunteers inhaled 1.5-2.0 mCi of FDG powder by a single deep breath. The distribution of radioactivity, measured by scanning during a period of 120 min, showed that the 18FDG powder deposition progressed from the central airways to the peripheral alveolar areas. In the tracheobronchial system the radioactivity decreased to 24% of the initial deposition at 60 min. In the peripheral alveolar area, where absorption into blood or lymphatic flow crossing the epithelial layer represents a unique mechanism of clearance for water-soluble 18FDG powder, alveolar radioactivity decreased slowly to approximately 70% of the initial deposition at 60 min after inhalation. Positron emission tomography using 18FDG powder provides a regional evaluation of both mucociliary transport in the tracheobronchial system and epithelial permeability in the alveolar area.
Absorption↗
Endoscopic bronchial polypectomy by high-frequency electric surgery.
Although polypectomy by high frequency electric surgery through the use of endoscopy has been widely applied to polypoid lesions in digestive canals, there have been very few reports of the treatment of bronchial lesions with this procedure. Recently, we have been successful in performing polypectomy without any complications using high-frequency electric surgery through a flexible bronchoscope in a patient with a benign bronchial polyp. Bronchial polypectomy by electric surgery has the advantages of preventing bleeding and providing large specimens for histological examination, compared with conventional methods, i.e. for forceps or laser methods.
Aged↗
Individual variation and mechanism of kanamycin ototoxicity in rabbits.
In order to elucidate the mechanism of individual variation of kanamycin ototoxicity, the possible relationship between the outer hair cell damage induced by kanamycin and the levels of kanamycin in serum or perilymph and of renal damage was investigated in rabbits. No relationship was found between the extent of the outer hair cell damage and the level of kanamycin in the serum or the renal damage. The extent of the outer hair cell damage was closely correlated to the levels of kanamycin in the perilymph. These findings suggest that the individual variations in the outer hair cell damage induced by kanamycin are more closely correlated to the individual differences in the transferability of kanamycin into inner ear than to those in the vulnerability of the outer hair cells or kidneys.
Animals↗