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T Aida

Publications and source records attributed to T Aida.

122 records · Page 7Linked to original sources
PubMed1982

[Germinoma originating in the basal ganglia--report of 2 cases].

We reported two cases of germinoma originating in the basal ganglia among the 50 cases of intracranial germinoma which were experienced at the Department of Neurosurgery, Hokkaido University Hospital. (Case 1) A 8-year-old boy was admitted to our hospital in October 1977, because of precocious puberty and left hemiparesis. Plain CT showed an irregularly-defined high density lesion in the right basal ganglia, which had several low density spots and was moderately enhanced on contrast CT. Endocrinological examination by radioimmunoassay revealed abnormally high level of serum luteinizing hormone and scanty level of serum follicle stimulating hormone. Beta-subunit of human chorionic gonadotropin (HCG) showed 46.4 ng/ml. Following radiation, the lesion on CT disappeared and beta-subunit turned to be in the normal range. It was concluded that the precocious puberty was due to hypersecretion of HCG by the tumor. About 2 years after the first admission, the tumors were disseminated to the spinal cord, followed several months later by the intracranial recurrence. The neurosurgical exploration was performed to both intracranial and spinal tumor lesions, which were proved to be germinoma by histological examination. Postoperative course was uneventful without recurrent signs. (Case 2) A 10-year-old boy was admitted to our hospital with 6-month history of right hemiparesis in February, 1979. CT at the first admission disclosed a slight high density lesion in the left basal ganglia, which had low density area suggesting cyst formation and was moderately enhanced on contrast CT. CT after one year showed multiple cysts in the tumor and displacement of neighboring structures. In February, 1980, a piece of the tumor was removed under bifrontal craniotomy and histologically diagnosed to be germinoma. Following radiation, the tumor disappeared on CT and his clinical features improved. In August, 1981, no recurrent signs were noted. From our 2 cases and review of the literature, it can be concluded that germinoma originating in the basal ganglia is rare and have high radiosensitivity as well as germinoma arising in the other sites, and common symptoms and signs are hemiparesis in all cases, not accompanied by intracranial hypertension in the early stage.

Basal Ganglia↗
PubMed1981

[Temporal lobe damage as pitfalls at subtemporal transtentorial approach (author's transl)].

It is essential to make a proper approach to the lesion site and retract brain, thereby securing an adequate field of vision, upon performing operations on patients for lesions of deep temporal lobe and tentorium. Although subtemporal transtentorial approaches to tumors in the tentorium, pyramis and cerebellopontine angle have been described by a number of workers, further studies have to be made on temporal lobe damage as a pitfall since only a few reports have been published to date. We have therefore examined the possible factors which are responsible for temporal lobe damage and brain swelling in six cases in which subtemporal transtentorial approaches were made. We have encountered two cases of meningioma of the pyramis and tentorium growing in the middle and posterior fossa, one case each of acoustic neurinoma and trigeminal neurinoma located in the middle and posterior fossa, one case of aneurysm at a marginal branch of the superior cerebellar artery and one case of arteriovenous malformation of the deep temporal lobe. Temporal lobe damage was observed in two of these cases during operation and in post-operative CT scans. Although no particular symptoms were noted, CT scan revealed temporal lobe damage in one case. One of the main factors responsible for temporal lobe damage is cutting major veins, namely inferior cerebral vein, transverse sinus, etc. However, no damage was resulted from cutting superior petrosal sinus. Intermittent release of the brain retractor and repeated use of hyperosmotic solution including ventricular drainage are recommended for preventing temporal lobe damage.

Adolescent↗
PubMed1980

Computerized tomography findings in dural arteriovenous malformations. Report of three cases.

Changes in the brain parenchyma and cerebrospinal fluid spaces were demonstrated in three cases of dural arteriovenous malformations by computerized tomography (CT). In various combinations, there were 1) vermiform or patchy enhancement after intravenous contrast infusion, 2) abnormal decreased density mainly in the white matter, 3) local mass effect, 4) hydrocephalus, 5) dilatation of the major venous sinus system, and 6) prominent vascular grooving of the skull inner table. Most of these changes were secondary to raised sinus pressure caused by arteriovenous shunt. It was also demonstrated by serial CT that some elements improved after artificial embolization or surgical excision of the malformations.

Aged↗
PubMed1979

[Three cases of brain injury due to windshield impact (author's transl)].

Three cases of brain injury due to windshield impact (tempered windshield) were reported. In the case of brain injury, multitude of small cracks injured the frontal lobe through the orbital roof with facial injuries due to windshield impact. Though we are apt to misdiagnose because of very small wounds, the diagnosis can be made easily from the plain film. The craniotomy, with complete removal of glass fragments and dural plasty, must be performed for the purpose of preventing infection and cerebrospinal fluid rhinorrhea. We believe that the use of seat belt and H.P.R. type laminated windshield is the best precaution against the windshield impact.

Accidents, Traffic↗
PubMedDate not supplied

Production of granulocyte-macrophage colony-stimulating factor by adult murine parenchymal liver cells (hepatocytes).

In order to investigate the hematolymphoid system in the adult murine liver, we examined colony-stimulating factor (CSF) released from primary cultured liver cell fractions, parenchymal and nonparenchymal liver cells (more than 99% pure. Using a fibrin clot culture system, we found colony-stimulating activity not only in the culture supernatant from nonparenchymal fraction of normal liver cells (NP-NLC sup), but also in the culture supernatant from parenchymal fraction of normal liver cells (P-NLC sup). Clusters and colonies, which were generated in 4-day cultures of bone marrow cells or spleen cells with P-NLC sup or NP-NLC sup, were mainly composed of granulocytes (G), macrophages (M), and granulocytes and macrophages (GM). Both P-NLC sup and NP-NLC sup proliferated IC2, which is a GM-CSF and IL-3 dependent cell line, and this proliferation was completely inhibited by rabbit anti-murine GM-CSF antibody. Furthermore, both Northern blot analysis and in situ hybridization with specific cDNA probe for murine GM-CSF showed that parenchymal liver cells expressed GM-CSF mRNA transcripts. The present findings indicate that cultured murine parenchymal liver cells produce GM-CSF. The possibility, therefore, is suggested that parenchymal liver cells also play an important role in the regional hematolymphoid system of the liver.

Animals↗