Biomedical subjects
Publications and source records attributed to T A Creagh.
Cyclosporine is associated with an increased incidence of graft primary non function and poorer long term graft function in patients with prolonged ischaemia times. We evaluated the role of hypothermia in preventing this synergism between the nephrotoxic effects of cyclosporine and ischaemia in a canine model. Induced renal hypothermia prevented this synergism.
Penetrating vascular injury which is associated with a satisfactory response to treatment occurs more commonly than blunt injury in the upper limb. Blunt trauma is a complex entity with associated soft tissue and skeletal injuries that may determine outcome irrespective of successful vascular repair. We reviewed 50 patients with upper limb vascular injury of which 43 were due to blunt trauma and seven to penetrating trauma. All patients with penetrating trauma had a good result without loss of limb function. Eight amputations and residual poor limb function in ten patients confirm the poor results of blunt injury. Associated nerve damage, responsible for nine of the ten poorly functioning limbs, is the most important determinant of outcome in limbs surviving the peri-traumatic period.
Explore the source record for details and available documents.
BACKGROUND: Primary lymphoma of the bladder is rare and its management is an evolving field. AIMS: To highlight primary lymphoma of the bladder as a possible diagnosis in cases of bladder neoplasm and to illustrate the currently favoured management options. METHODS: Three cases of primary bladder lymphoma are reported and management is reviewed. RESULTS: Each of the three cases was managed differently with each management approach yielding a favourable outcome. CONCLUSION: Chemotherapy combined, if necessary, with surgery or radiation therapy, should be the standard of care, depending on the full histological diagnosis.
Explore the source record for details and available documents.