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Biomedical subjects

T A Bal'magiia

Publications and source records attributed to T A Bal'magiia.

10 recordsLinked to original sources
PubMed1975

[Acceleration].

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Acceleration↗
PubMed1975

[Mechanisms of the effect of orotic acid on the growth and development of young rats].

Chronic administration to ratlings of potassium orotate in a dose of 75 mg/kg from the 5th to the 14th day and of 150 mg/kg from the 15th to the 30th day after birth led to a significant acceleration of growth and functional maturation of the animals. The rate of growth in the experimental ratlings was much greater at periods of from the 5th to the 14th and from the 21st to the 30th days than in control animals, but showed no significant difference on the 14th-20th days. Growth acceleration at the period of from the 5th to the 14th days dues to a higher (in comparison with control) activity of the vegetative systems (increased oxygen consumption, frequency of respiration and cardiac contractions at rest). On the 21st-30th days growth acceleration in the experimental animals was associated with an earlier reduction in the activity of the vegetative systems and of the sympathico-adrenal regulation mechanisms, this being pointed to by a fall in catecholamine content in the adrenal glands and the brain.

Acetylcholinesterase↗
PubMedDate not supplied

[Changes in the concentrations and synthesis of DNA and RNA in tissues during accelerated growth and development of rats].

Daily administration of low doses of caffeine to 5-30 day old rats increases their growth, mainly due to the increase in muscle weight and results in acceleration of maturation of vegetative functions. DNA and total RNA levels in skeletal muscles and liver increase together with the increase of incorporation of labeled uridine and lysin into total RNA and proteins. These findings indicate stimulation of protein synthesis in these tissues. Significant increase in the relative weight of the thymus, its DNA and RNA contents, as well as its uridine-14C uptake may indicate anabolic effects of this gland upon growth. In control and experimental animals, the level of DNA and RNA in the thymus is 5-10 times higher as compared to that in muscles, liver and heart.

Animals↗