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Biomedical subjects

Susan Philip

Publications and source records attributed to Susan Philip.

2 recordsLinked to original sources

Overview and commentary.

The California Health Benefits Review Program (CHBRP)--established in 2003 in response to new state legislation aimed at enhancing the evaluation of potential changes in health benefit packages--represents a unique marriage of academic analysis and real-time legislative decision making. CHBRP is based within the University of California (UC) Office of the President and provides analyses to the legislature within a 60-day timeframe on the potential consequences of specific benefit changes under consideration as part of legislative mandates. The consequences examined include current known medical effectiveness of the services for which coverage is to be mandated as well as potential costs and impact on public health considerations associated with the mandate. Teams throughout the University system specialize in analyzing medical effectiveness, costs, and public health impacts and work with a statewide faculty task force and a private actuarial firm to generate literature reviews and analyses in response to legislative requests. These teams work on multiple requests simultaneously, all within the constraints of the legislative calendar. In its first 2 years, CHBRP generated 22 such analyses.

California↗

Modification of the synaptic glutamate turnover in the hippocampal tissue exposed to low-frequency, pulsed magnetic fields.

The influence of pulsed magnetic fields (PMF) on the release and uptake of glutamate was investigated. While the release was examined using hippocampal slices, synaptosomes were chosen to characterize the uptake process. (3)H-D-aspartate was used as a marker of glutamergic transmission. The pulsed magnetic fields (9-15 mT) applied according to the pattern which induced epileptic discharges in hippocampus amplified and attenuated the release and uptake of glutamate, respectively. However, the magnetic fields which induced an increase in neuronal excitability without concomitant seizures amplified both processes. These results confirm our previous reports and indicate that the glutamergic synapses are the target of magnetic fields action.

Animals↗