Complete mediastinal lymph node dissection---does it make a difference?
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Clinical Trials, Phase III as Topic↗
Biomedical subjects
Steven M Keller
Publications and source records attributed to Steven M Keller.
Neoadjuvant and adjuvant therapy of non-small cell lung cancer.
Though surgery offers the best chance of cure for patients with non-small cell lung cancer (NSCLC), many patients who undergo complete tumor resection will die of recurrent disease. Chemotherapy and radiotherapy have been employed both individually and in combination in an effort to prevent local recurrence and extrathoracic metastatic disease. However, the administration of neoadjuvant or adjuvant therapy remains controversial. Phase II and III trials with traditional radiotherapy schedules and cytotoxic drugs have produced conflicting results. Novel approaches utilizing long-term administration of less toxic drugs and targeted biologic therapies are promising.
Carcinoma, Non-Small-Cell Lung↗