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Biomedical subjects

Steven Edwards

Publications and source records attributed to Steven Edwards.

9 recordsLinked to original sources

Lecturers' unions.

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Attitude of Health Personnel↗

OFFLU network on avian influenza.

OFFLU is the name of the network of avian influenza expertise inaugurated jointly in 2005 by the Food and Agriculture Organization of the United Nations and the World Organisation for Animal Health. Achievements and constraints to date and plans for the future are described.

Animals↗

Human death.

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Attitude to Death↗

Moral theory.

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Ethical Theory↗

The crystal structure of anthranilate phosphoribosyltransferase from the enterobacterium Pectobacterium carotovorum.

The structure of anthranilate phosphoribosyltransferase from the enterobacterium Pectobacterium carotovorum has been solved at 2.4 A in complex with Mn(2+)-pyrophosphate, and at 1.9 A without ligands. The enzyme structure has a novel phosphoribosyltransferase (PRT) fold and displays close homology to the structures of pyrimidine nucleoside phosphorylases. The enzyme is a homodimer with a monomer of 345 residues. Each monomer consists of two subdomains, alpha and alpha/beta, which form a cleft containing the active site. The nature of the active site is inferred from the trapped MnPPi complex and detailed knowledge of the active sites of nucleoside phosphorylases. With the anthranilate (An)PRT structure solved, the structures of all the enzymes required for tryptophan biosynthesis are now known.

Amino Acid Sequence↗