Biomedical subjects
Publications and source records attributed to Steven C Sieber.
We herein describe an atypical presentation of a migrating coelomic cyst attached to a pedicle of pericardial fat pad in an asymptomatic 45-year-old woman. A review of the English-language literature revealed only one such case report.
Malignant transformation of eccrine spiradenoma is extremely rare. We describe the case of a 70-year-old man with malignant eccrine spiradenoma of the forearm and metastases to the axillary lymph nodes. Surgical excision with adequate margins and lymph node dissection was performed. Tamoxifen therapy was instituted after obtaining positive immunostaining results for estrogen receptor. After 41 months of follow-up, there has been no recurrence or distant metastases. Wide local excision and close follow-up are crucial in the management of malignant eccrine spiradenoma. The role of other therapeutic modalities, including hormonal therapy, remains to be determined.